Search Results - "Toschi, Elena"

The Janus Face of Tumor Microenvironment Targeted by Immunotherapy by Buoncervello, Maria, Gabriele, Lucia, Toschi, Elena

“…The tumor microenvironment (TME) is a complex entity where host immune and non-immune cells establish a dynamic crosstalk with cancer cells. Through cell-cell…”
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3D Microfluidic model for evaluating immunotherapy efficacy by tracking dendritic cell behaviour toward tumor cells by Parlato, Stefania, De Ninno, Adele, Molfetta, Rosa, Toschi, Elena, Salerno, Debora, Mencattini, Arianna, Romagnoli, Giulia, Fragale, Alessandra, Roccazzello, Lorenzo, Buoncervello, Maria, Canini, Irene, Bentivegna, Enrico, Falchi, Mario, Bertani, Francesca Romana, Gerardino, Annamaria, Martinelli, Eugenio, Natale, Corrado, Paolini, Rossella, Businaro, Luca, Gabriele, Lucia

“…Immunotherapy efficacy relies on the crosstalk within the tumor microenvironment between cancer and dendritic cells (DCs) resulting in the induction of a…”
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A parallel randomised controlled trial of the Hypoglycaemia Awareness Restoration Programme for adults with type 1 diabetes and problematic hypoglycaemia despite optimised self-care (HARPdoc) by Amiel, Stephanie A., Potts, Laura, Goldsmith, Kimberley, Jacob, Peter, Smith, Emma L., Gonder-Frederick, Linda, Heller, Simon, Toschi, Elena, Brooks, Augustin, Kariyawasam, Dulmini, Choudhary, Pratik, Stadler, Marietta, Rogers, Helen, Kendall, Mike, Sevdalis, Nick, Bakolis, Ioannis, de Zoysa, Nicole

“…Impaired awareness of hypoglycaemia (IAH) is a major risk for severe hypoglycaemia in insulin treatment of type 1 diabetes (T1D). To explore the hypothesis…”
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Utility of Continuous Glucose Monitoring in Type 1 and Type 2 Diabetes by Toschi, Elena, MD, Wolpert, Howard, MD

“…A consensus conference of the American Association of Clinical Endocrinologists and American College of Endocrinology held in February 2016 advocated expanding…”
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HIV-1 TAT and IMMUNE DYSREGULATION in AIDS PATHOGENESIS: a THERAPEUTIC TARGET by Chiozzini, Chiara, Toschi, Elena

“…The HIV-1 transactivator Tat protein plays a key role in AIDS pathogenesis. Besides the Tat role as activator of HIV-1 transcription, it exerts several…”
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Fructose ingestion acutely stimulates circulating FGF21 levels in humans by Dushay, Jody R, Toschi, Elena, Mitten, Emilie K, Fisher, Ffolliott M, Herman, Mark A, Maratos-Flier, Eleftheria

“…Abstract Objective Fibroblast growth factor 21 (FGF21) is a hormone with pleiotropic metabolic activities which, in rodents, is robustly regulated by fasting…”
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Mini-Dose Glucagon as a Novel Approach to Prevent Exercise-Induced Hypoglycemia in Type 1 Diabetes by Rickels, Michael R, DuBose, Stephanie N, Toschi, Elena, Beck, Roy W, Verdejo, Alandra S, Wolpert, Howard, Cummins, Martin J, Newswanger, Brett, Riddell, Michael C

“…Patients with type 1 diabetes who do aerobic exercise often experience a drop in blood glucose concentration that can result in hypoglycemia. Current…”
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Self-care barriers and facilitators in older adults with T1D during a time of sudden isolation by Munshi, Medha, Slyne, Christine, Weinger, Katie, Sy, Sarah, Sifre, Kayla, Michals, Amy, Davis, Dai’Quann, Dewar, Rachel, Atakov-Castillo, Astrid, Haque, Saira, Cummings, M. Stirling, Brown, Stephen L., Toschi, Elena

“…Older adults with type 1 diabetes (T1D) have unique challenges and needs. In this mixed-methods study, we explored the impact of isolation during a pandemic on…”
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Drugs and convalescent plasma therapy for COVID-19: a survey of the interventional clinical studies in Italy after 1 year of pandemic by Puopolo, Maria, Morciano, Cristina, Buoncervello, Maria, De Nuccio, Chiara, Potenza, Rosa Luisa, Toschi, Elena, Palmisano, Lucia

“…Abstract Background The 2019 novel coronavirus disease (COVID-19) pandemic has highlighted the importance of health research and fostered clinical research as…”
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Weight Loss Outcomes Among Early High Responders to Exenatide Treatment: A Randomized, Placebo Controlled Study in Overweight and Obese Women by Rodgers, Megan, Migdal, Alexandra L, Rodríguez, Tahereh Ghorbani, Chen, Zsu-Zsu, Nath, Anjali K, Gerszten, Robert E, Kasid, Natasha, Toschi, Elena, Tripaldi, Juliet, Heineman, Brent, Phan, Minh, Ngo, Long, Maratos-Flier, Eleftheria, Dushay, Jody

“…As there is significant heterogeneity in the weight loss response to pharmacotherapy, one of the most important clinical questions in obesity medicine is how…”
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Ecology and Management of a Large Outbreak of Avian Botulism in Wild Waterbirds in Northeastern Italy (2019-2022) by Volponi, Stefano, De Marco, Maria Alessandra, Benigno, Roberta, Savorelli, Enea, Frasnelli, Matteo, Fiorentini, Laura, Tosi, Giovanni, Bardasi, Lia, Toschi, Elena, Taddei, Roberta, Cocchi, Roberto

“…Avian botulism is a paralytic disease due to the ingestion of botulinum neurotoxins (BoNT) produced by anaerobic, sporigenic bacteria (notably, ). Wild…”
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Caring for Young Adults With Diabetes in the Adult Care Setting: Summary of a Multidisciplinary Roundtable by Toschi, Elena, Leblanc, Jennifer, Hafida, Samar, Mehta, Sanjeev, Ritholz, Marilyn, Gabbay, Robert, Laffel, Lori

“…A multidisciplinary team of clinicians and researchers, patients and family members, and representative from national advocacy groups and research organization…”
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Clustering of Insulin Resistance With Vascular Dysfunction and Low-Grade Inflammation in Type 2 Diabetes by NATALI, Andrea, TOSCHI, Elena, BALDEWEG, Stephanie, CIOCIARO, Demetrio, FAVILLA, Stefania, SACCA, Luigi, FERRANNINI, Ele

“…Clustering of Insulin Resistance With Vascular Dysfunction and Low-Grade Inflammation in Type 2 Diabetes Andrea Natali 1 , Elena Toschi 1 , Stephanie Baldeweg…”
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Type 1 Diabetes and Aging by Toschi, Elena

“…The number of older adults with type 1 diabetes (T1D) is increasing due to an overall increase in life expectancy and improvement in diabetes management and…”
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Human immunodeficiency virus protease inhibitors reduce the growth of human tumors via a proteasome‐independent block of angiogenesis and matrix metalloproteinases by Toschi, Elena, Sgadari, Cecilia, Malavasi, Laura, Bacigalupo, Ilaria, Chiozzini, Chiara, Carlei, Davide, Compagnoni, Daniela, Bellino, Stefania, Bugarini, Roberto, Falchi, Mario, Palladino, Clelia, Leone, Patrizia, Barillari, Giovanni, Monini, Paolo, Ensoli, Barbara

“…Human immunodeficiency virus protease inhibitors (HIV‐PIs), such as indinavir and saquinavir, have been shown to block angiogenesis and tumor cell invasion and…”
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Vascular Effects of Improving Metabolic Control With Metformin or Rosiglitazone in Type 2 Diabetes by NATALI, Andrea, BALDEWEG, Stephanie, TOSCHI, Elena, CAPALDO, Brunella, BARBARO, Daniele, GASTALDELLI, Amalia, YUDKIN, John S, FERRANNINI, El E

“…Vascular Effects of Improving Metabolic Control With Metformin or Rosiglitazone in Type 2 Diabetes Andrea Natali , MD 1 , Stephanie Baldeweg , MD 2 , Elena…”
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Use of Telecommunication and Diabetes-Related Technologies in Older Adults With Type 1 Diabetes During a Time of Sudden Isolation: Mixed Methods Study by Toschi, Elena, Slyne, Christine, Weinger, Katie, Sy, Sarah, Sifre, Kayla, Michals, Amy, Davis, DaiQuann, Dewar, Rachel, Atakov-Castillo, Astrid, Haque, Saira, Cummings, Stirling, Brown, Stephen, Munshi, Medha

“…The COVID-19 lockdown imposed a sudden change in lifestyle with self-isolation and a rapid shift to the use of technology to maintain clinical care and social…”
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The pancreatic ductal epithelium serves as a potential pool of progenitor cells by Bonner-Weir, Susan, Toschi, Elena, Inada, Akari, Reitz, Petra, Fonseca, Sonya Y., Aye, Tandy, Sharma, Arun

“…:  With the increasing success of islet transplantation, β‐cell replacement therapy has had renewed interest. To make such a therapy available to more than a…”
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Shiga toxin-producing Escherichia coli in slaughtered pigs and pork products by Bardasi, Lia, Taddei, Roberta, Fiocchi, Ilaria, Pelliconi, Maria Francesca, Ramini, Mattia, Toschi, Elena, Merialdi, Giuseppe

“…During the years 2015-2016, 83 faecal samples were collected at slaughter from pigs reared in farms located in Central- Northern Italy. During the years…”
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Apicidin and Docetaxel Combination Treatment Drives CTCFL Expression and HMGB1 Release Acting as Potential Antitumor Immune Response Inducers in Metastatic Breast Cancer Cells by Buoncervello, Maria, Borghi, Paola, Romagnoli, Giulia, Spadaro, Francesca, Belardelli, Filippo, Toschi, Elena, Gabriele, Lucia

“…Abstract Currently approved combination regimens available for the treatment of metastatic tumors, such as breast cancer, have been shown to increase response…”
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