Search Results - "Toscani, Denise"

Refine Results
  1. 1
  2. 2

    The Metabolic Features of Osteoblasts: Implications for Multiple Myeloma (MM) Bone Disease by Lungu, Oxana, Toscani, Denise, Burroughs-Garcia, Jessica, Giuliani, Nicola

    “…The study of osteoblast (OB) metabolism has recently received increased attention due to the considerable amount of energy used during the bone remodeling…”
    Get full text
    Journal Article
  3. 3
  4. 4

    Adenosine Generated in the Bone Marrow Niche Through a CD38-Mediated Pathway Correlates with Progression of Human Myeloma by Horenstein, Alberto L, Quarona, Valeria, Toscani, Denise, Costa, Federica, Chillemi, Antonella, Pistoia, Vito, Giuliani, Nicola, Malavasi, Fabio

    Published in Molecular medicine (Cambridge, Mass.) (01-01-2016)
    “…Human myeloma cells express CD38 at high levels and grow in hypoxic niches inside the bone marrow. Myeloma cells respond to hypoxia with metabolic changes…”
    Get full text
    Journal Article
  5. 5

    CD14+CD16+ monocytes are involved in daratumumab‐mediated myeloma cells killing and in anti‐CD47 therapeutic strategy by Storti, Paola, Vescovini, Rosanna, Costa, Federica, Marchica, Valentina, Toscani, Denise, Dalla Palma, Benedetta, Craviotto, Luisa, Malavasi, Fabio, Giuliani, Nicola

    Published in British journal of haematology (01-08-2020)
    “…Summary A deep elucidation of the mechanisms of action of anti‐CD38 monoclonal antibodies (mAbs), such as daratumumab (DARA), is required to identify patients…”
    Get full text
    Journal Article
  6. 6

    Mechanism of Action of Bortezomib and the New Proteasome Inhibitors on Myeloma Cells and the Bone Microenvironment: Impact on Myeloma-Induced Alterations of Bone Remodeling by Aversa, Franco, Dalla Palma, Benedetta, Bolzoni, Marina, Toscani, Denise, Accardi, Fabrizio, Giuliani, Nicola

    Published in BioMed research international (01-01-2015)
    “…Multiple myeloma (MM) is characterized by a high capacity to induce alterations in the bone remodeling process. The increase in osteoclastogenesis and the…”
    Get full text
    Journal Article
  7. 7

    The Proteasome and Myeloma-Associated Bone Disease by Accardi, Fabrizio, Toscani, Denise, Costa, Federica, Aversa, Franco, Giuliani, Nicola

    Published in Calcified tissue international (01-02-2018)
    “…Bone disease is the hallmark of multiple myeloma (MM), a hematological malignancy characterized by osteolytic lesions due to a severe uncoupled and unbalanced…”
    Get full text
    Journal Article
  8. 8

    Molecular Features of the Mesenchymal and Osteoblastic Cells in Multiple Myeloma by Iannozzi, Nicolas Thomas, Marchica, Valentina, Toscani, Denise, Burroughs Garcìa, Jessica, Giuliani, Nicola, Storti, Paola

    “…Multiple myeloma (MM) is a monoclonal gammopathy characterized by biological heterogeneity and unregulated proliferation of plasma cells (PCs) in bone marrow…”
    Get full text
    Journal Article
  9. 9
  10. 10
  11. 11

    Metabolic features of myeloma cells in the context of bone microenvironment: Implication for the pathophysiology and clinic of myeloma bone disease by Raimondi, Vincenzo, Toscani, Denise, Marchica, Valentina, Burroughs-Garcia, Jessica, Storti, Paola, Giuliani, Nicola

    Published in Frontiers in oncology (13-10-2022)
    “…Multiple myeloma (MM) is a hematological malignancy characterized by the accumulation of malignant plasma cells (PCs) into the bone marrow (BM). The complex…”
    Get full text
    Journal Article
  12. 12

    The Role of Proteasome Inhibitors in Multiple Myeloma Bone Disease and Bone Metastasis: Effects on Osteoblasts and Osteocytes by Toscani, Denise, Craviotto, Luisa, Giuliani, Nicola

    Published in Applied sciences (01-05-2021)
    “…The alterations of bone remodeling are typical of multiple myeloma (MM) patients where the uncoupled and unbalanced bone remodeling caused the onset of…”
    Get full text
    Journal Article
  13. 13
  14. 14
  15. 15
  16. 16

    [18F](2S,4R)-4-Fluoroglutamine as a New Positron Emission Tomography Tracer in Myeloma by Valtorta, Silvia, Toscani, Denise, Chiu, Martina, Sartori, Andrea, Coliva, Angela, Brevi, Arianna, Taurino, Giuseppe, Grioni, Matteo, Ruffini, Livia, Vacondio, Federica, Zanardi, Franca, Bellone, Matteo, Moresco, Rosa Maria, Bussolati, Ovidio, Giuliani, Nicola

    Published in Frontiers in oncology (12-10-2021)
    “…The high glycolytic activity of multiple myeloma (MM) cells is the rationale for use of Positron Emission Tomography (PET) with 18 F-fluorodeoxyglucose ([ 18…”
    Get full text
    Journal Article
  17. 17

    Role of 1q21 in Multiple Myeloma: From Pathogenesis to Possible Therapeutic Targets by Burroughs Garcìa, Jessica, Eufemiese, Rosa Alba, Storti, Paola, Sammarelli, Gabriella, Craviotto, Luisa, Todaro, Giannalisa, Toscani, Denise, Marchica, Valentina, Giuliani, Nicola

    Published in Cells (Basel, Switzerland) (01-06-2021)
    “…Multiple myeloma (MM) is characterized by an accumulation of malignant plasma cells (PCs) in the bone marrow (BM). The amplification of 1q21 is one of the most…”
    Get full text
    Journal Article
  18. 18
  19. 19
  20. 20

    Role of Osteocytes in Myeloma Bone Disease: Anti-sclerostin Antibody as New Therapeutic Strategy by Toscani, Denise, Bolzoni, Marina, Ferretti, Marzia, Palumbo, Carla, Giuliani, Nicola

    Published in Frontiers in immunology (24-10-2018)
    “…Osteocytes are terminally differentiated cells of the osteoblast lineage. They are involved in the regulation of bone remodeling by increasing osteoclast…”
    Get full text
    Journal Article