Search Results - "Tosca, Lucie"
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Transplantation of Human Embryonic Stem Cell–Derived Cardiovascular Progenitors for Severe Ischemic Left Ventricular Dysfunction
Published in Journal of the American College of Cardiology (30-01-2018)“…In addition to scalability, human embryonic stem cells (hESCs) have the unique advantage of allowing their directed differentiation toward lineage-specific…”
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Adiponectin increases insulin-like growth factor I-induced progesterone and estradiol secretion in human granulosa cells
Published in Fertility and sterility (01-12-2009)“…Objective To identify adiponectin and its receptors (AdipoR1 and AdipoR2) in human granulosa cells (GC) and to study the effects of recombinant human…”
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Towards a clinical use of human embryonic stem cell-derived cardiac progenitors: a translational experience
Published in European heart journal (21-03-2015)“…There is now compelling evidence that cells committed to a cardiac lineage are most effective for improving the function of infarcted hearts. This has been…”
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Risk of tumorigenicity in mesenchymal stromal cell–based therapies—Bridging scientific observations and regulatory viewpoints
Published in Cytotherapy (Oxford, England) (01-07-2013)“…Abstract In the past decade, the therapeutic value of mesenchymal stromal cells (MSCs) has been studied in various indications, thereby taking advantage of…”
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Genomic Alterations and Complex Subclonal Architecture in Sporadic GH-Secreting Pituitary Adenomas
Published in The journal of clinical endocrinology and metabolism (01-05-2018)“…Abstract Purpose The molecular pathogenesis of growth hormone-secreting pituitary adenomas is not fully understood. Cytogenetic alterations might serve as…”
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Improved functionality of hepatic spheroids cultured in acoustic levitation compared to existing 2D and 3D models
Published in Scientific reports (14-09-2024)“…Hepatic spheroids are of high interest in basic research, drug discovery and cell therapy. Existing methods for spheroid culture present advantages and…”
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Regulation of adiponectin and its receptors in rat ovary by human chorionic gonadotrophin treatment and potential involvement of adiponectin in granulosa cell steroidogenesis
Published in Reproduction (Cambridge, England) (01-04-2007)“…In mammals, adiponectin and its receptors (AdipoR1 and AdipoR2) mRNAs are expressed in various tissues. However, the cellular expression and the role of…”
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Chromosomal translocations and semen quality: A study on 144 male translocation carriers
Published in Reproductive biomedicine online (01-01-2019)“…Chromosomal translocations are known genetic causes of male infertility. Are certain translocations or chromosomal regions more directly associated with sperm…”
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Hypermethylator Phenotype and Ectopic GIP Receptor in GNAS Mutation-Negative Somatotropinomas
Published in The journal of clinical endocrinology and metabolism (01-05-2019)“…Abstract Context Besides GNAS gene mutations, the molecular pathogenesis of somatotroph adenomas responsible for gigantism and acromegaly remains elusive…”
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iPSCs derived from infertile men carrying complex genetic abnormalities can generate primordial germ-like cells
Published in Scientific reports (22-08-2022)“…Despite increasing insight into the genetics of infertility, the developmental disease processes remain unclear due to the lack of adequate experimental…”
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In Vitro Gamete Differentiation from Pluripotent Stem Cells as a Promising Therapy for Infertility
Published in Stem cells and development (01-04-2016)“…Generation of gametes derived in vitro from pluripotent stem cells holds promising prospects for future reproductive applications. Indeed, it provides…”
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Metformin decreases IGF1-induced cell proliferation and protein synthesis through AMP-activated protein kinase in cultured bovine granulosa cells
Published in Reproduction (Cambridge, England) (01-02-2010)“…Although its mechanism of action is still unclear, metformin is an anti-diabetic drug effective to restore cyclicity and spontaneous ovulation in women with…”
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Expression of adiponectin and its receptors (AdipoR1 and AdipoR2) in chicken ovary: Potential role in ovarian steroidogenesis
Published in Domestic animal endocrinology (01-11-2007)“…Adiponectin and its receptors (AdipoR1 and AdipoR2) mRNAs are expressed in various chicken tissues including ovary. However, the cellular expression and the…”
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Different routes lead to apoptosis in unfertilized sea urchin eggs
Published in Apoptosis (London) (01-03-2014)“…Results obtained in various species, from mammals to invertebrates, show that arrest in the cell cycle of mature oocytes is due to a high ERK activity…”
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Adenosine 5′-Monophosphate-Activated Protein Kinase Regulates Progesterone Secretion in Rat Granulosa Cells
Published in Endocrinology (Philadelphia) (01-10-2005)“…The AMP-activated protein kinase (AMPK) is a major regulator of energy metabolism involved in fatty acid and cholesterol synthesis. In the ovary, cholesterol…”
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Effects of high levels of glucose on the steroidogenesis and the expression of adiponectin receptors in rat ovarian cells
Published in Reproductive biology and endocrinology (19-03-2008)“…Reproductive dysfunction in the diabetic female rat is associated with altered folliculogenesis and steroidogenesis. However, the molecular mechanisms involved…”
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Adrenal GIPR expression and chromosome 19q13 microduplications in GIP-dependent Cushing's syndrome
Published in JCI insight (21-09-2017)“…GIP-dependent Cushing's syndrome is caused by ectopic expression of glucose-dependent insulinotropic polypeptide receptor (GIPR) in cortisol-producing adrenal…”
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Two new cases of interstitial 7q35q36.1 deletion including CNTNAP2 and KMT2C
Published in Molecular genetics & genomic medicine (01-11-2021)“…Background Terminal deletions of the long arm of chromosome 7 are well known and frequently associated with syndromic holoprosencephaly due to the involvement…”
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AMP-activated protein kinase activation modulates progesterone secretion in granulosa cells from hen preovulatory follicles
Published in Journal of endocrinology (01-07-2006)“…AMP-activated protein kinase (AMPK) is a fuel sensor in glucose, lipid, and cholesterol metabolism. Using RT-PCR and Western blot, AMPK subunits mRNAs (α1/2,…”
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Transplantation of Macaca cynomolgus iPS-derived hematopoietic cells in NSG immunodeficient mice
Published in Haematologica (Roma) (01-10-2015)Get full text
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