Search Results - "Tortolero, María"

Loss of FBXW7 and accumulation of MCL1 and PLK1 promote paclitaxel resistance in breast cancer by Gasca, Jessica, Flores, Maria Luz, Giráldez, Servando, Ruiz-Borrego, Manuel, Tortolero, María, Romero, Francisco, Japón, Miguel A, Sáez, Carmen

“…FBXW7 is a component of SCF (complex of SKP1, CUL1 and F-box-protein)-type ubiquitin ligases that targets several oncoproteins for ubiquitination and…”
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Obatoclax and Paclitaxel Synergistically Induce Apoptosis and Overcome Paclitaxel Resistance in Urothelial Cancer Cells by Jiménez-Guerrero, Rocío, Gasca, Jessica, Flores, M Luz, Pérez-Valderrama, Begoña, Tejera-Parrado, Cristina, Medina, Rafael, Tortolero, María, Romero, Francisco, Japón, Miguel A, Sáez, Carmen

“…Paclitaxel is a treatment option for advanced or metastatic bladder cancer after the failure of first-line cisplatin and gemcitabine, although resistance…”
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Prostate cancer cell response to paclitaxel is affected by abnormally expressed securin PTTG1 by Castilla, Carolina, Flores, M Luz, Medina, Rafael, Pérez-Valderrama, Begoña, Romero, Francisco, Tortolero, María, Japón, Miguel A, Sáez, Carmen

“…PTTG1 protein, the human securin, has a central role in sister chromatid separation during mitosis, and its altered expression has been reported in many tumor…”
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Protein Phosphatase 2A Stabilizes Human Securin, Whose Phosphorylated Forms Are Degraded via the SCF Ubiquitin Ligase by Gil-Bernabé, Ana M., Romero, Francisco, Limón-Mortés, M. Cristina, Tortolero, María

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Expression of pituitary tumor–transforming gene 1 (PTTG1)/securin in hepatitis B virus (HBV)‐associated liver diseases: Evidence for an HBV X protein–mediated inhibition of PTTG1 ubiquitination and degradation by Molina‐Jiménez, Francisca, Benedicto, Ignacio, Murata, Miki, Martín‐Vílchez, Samuel, Seki, Toshihito, Antonio Pintor‐Toro, José, Tortolero, María, Moreno‐Otero, Ricardo, Okazaki, Kazuichi, Koike, Kazuhiko, Barbero, José Luchi, Matsuzaki, Koichi, Majano, Pedro L., López‐Cabrera, Manuel

“…Chronic infection with hepatitis B virus (HBV) is strongly associated with hepatocellular carcinoma (HCC), and the viral HBx protein plays a crucial role in…”
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Human securin interacts with p53 and modulates p53-mediated transcriptional activity and apoptosis by Pintor-Toro, José A, Romero, Francisco, Luna, Rosa, Ramos-Morales, Francisco, Tortolero, María, Silva, Augusto, Bernal, Juan A, Espina, Águeda, Lázaro, Icíar, Arias, Carmen

“…The gene PTTG1 (encoding the pituitary tumor-transforming 1 protein) is overexpressed in several different tumor types, is tumorigenic in vivo and shows…”
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UV-induced degradation of securin is mediated by SKP1-CUL1-βTrCP E3 ubiquitin ligase by Limón-Mortés, M. Cristina, Mora-Santos, Mar, Espina, Águeda, Pintor-Toro, José A, López-Román, Antonio, Tortolero, María, Romero, Francisco

“…Securin is a chaperone protein with bifunctional properties. It binds to separase to inhibit premature sister chromatid separation until the onset of anaphase,…”
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Prognostic Significance of Human Pituitary Tumor-Transforming Gene Immunohistochemical Expression in Differentiated Thyroid Cancer by Sáez, Carmen, Martínez-Brocca, M. Asunción, Castilla, Carolina, Soto, Alfonso, Navarro, Elena, Tortolero, María, Pintor-Toro, José A., Japón, Miguel A.

“…Context: Human securin pituitary tumor-transforming gene (hPTTG) is overexpressed in a variety of primary neoplasias, including differentiated thyroid cancer…”
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Typical esthetic outcomes using 5 different modalities to treat MIH affected teeth: a case series by Natera-Guarapo, Alfredo, Rodríguez-Rodríguez, Mónica, Acosta-de Camargo, Maria Gabriela, Pimentel, Eva, Begoña-Tortolero, María

“…Introduction: therapeutic options for incisors affected by Molar Incisor Hypomineralization range from very conservative procedures to those considered to be…”
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hpttg, a human homologue of rat pttg, is overexpressed in hematopoietic neoplasms. Evidence for a transcriptional activation function of hPTTG by DOMINGUEZ, A, RAMOS-MORALES, F, ROMERO, F, RIOS, R. M, DREYFUS, F, TORTOLERO, M, PINTOR-TORO, J. A

“…We have isolated a human cDNA clone encoding a novel protein of 22 kDa that is a human counterpart of the rat oncoprotein PTTG. We show that the corresponding…”
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hpttg is over-expressed in pituitary adenomas and other primary epithelial neoplasias by SAEZ, C, JAPON, M. A, RAMOS-MORALES, F, ROMERO, F, SEGURA, D. I, TORTOLERO, M, PINTOR-TORO, J. A

“…The role of oncogenes in pituitary tumorigenesis remains elusive since few genetic changes have been identified so far in pituitary tumors. Pituitary…”
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Human securin, hPTTG, is associated with Ku heterodimer, the regulatory subunit of the DNA-dependent protein kinase by Romero, F, Multon, M C, Ramos-Morales, F, Domínguez, A, Bernal, J A, Pintor-Toro, J A, Tortolero, M

“…We have previously isolated the hpttg proto-oncogene, which is expressed in normal tissues containing proliferating cells and in several kinds of tumors. In…”
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Expression of hpttg proto-oncogene in lymphoid neoplasias by SAEZ, Carmen, PEREDA, Teresa, BORRERO, Juan J, ESPINA, Agueda, ROMERO, Francisco, TORTOLERO, Maria, PINTOR-TORO, José A, SEGURA, Dolores I, JAPON, Miguel A

“…Pituitary tumor-transforming gene (pttg) is a distinct proto-oncogene which is expressed in certain normal tissues with high proliferation rate and in a…”
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Securin Is a Target of the UV Response Pathway in Mammalian Cells by Romero, Francisco, Gil-Bernabé, Ana M, Sáez, Carmen, Japón, Miguel A, Pintor-Toro, José A, Tortolero, María

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nasST, two genes involved in the induction of the assimilatory nitrite-nitrate reductase operon (nasAB) of Azotobacter vinelandii by Gutierrez, J C, Ramos, F, Ortner, L, Tortolero, M

“…An operon including two new genes (nasS and nasT) has been defined, cloned and sequenced. The deduced NASS protein is homologous to NRTA from Synechococcus sp…”
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Blanqueamiento dental en niños y adolescentes ¿El epílogo de un mito? Revisión de la Literatura by Acosta de Camargo, Maria Gabriela, Natera, Alfredo, Rodriguez, Monica, Pimentel, Eva, Tortolero, María Begoña

“…Introducción: En torno al blanqueamiento dental existen muchas afirmaciones con poco soporte científico, tales como: los blanqueamientos son ácidos, dañan el…”
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Grb2 and Its Apoptotic Isoform Grb3-3 Associate with Heterogeneous Nuclear Ribonucleoprotein C, and These Interactions Are Modulated by Poly(U) RNA by Romero, F, Ramos-Morales, F, Domínguez, A, Rios, R M, Schweighoffer, F, Tocqué, B, Pintor-Toro, J A, Fischer, S, Tortolero, M

“…Grb2 is an adaptor molecule comprising one Src homology (SH) 2 and two SH3 domains. This protein has a natural isoform named Grb3-3 with a deletion within the…”
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Adenosine Deaminase Is a Specific Partner for the Grb2 Isoform Grb3-3 by Ramos-Morales, Francisco, Domı́nguez, Africa, Rios, Rosa M., Barroso, Sonia I., Infante, Carlos, Schweighoffer, Fabien, Tocqué, Bruno, Pintor-Toro, José A., Tortolero, Marı́a

“…Grb3-3 is an isoform of Grb2, thought to arise by alternative splicing, that lacks a functional SH2 domain but retains functional SH3 domains, which allow…”
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Taste Discrimination after Separate Pre-Exposure and Test Sessions by Begoñatortolero, María, Acosta, María Gabriela, Espinet, Alfredo

“…The effect of previous exposure on discrimination of two flavored solutions sharing a common taste was investigated in a pilot experiment. These solutions were…”
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Cell cycle regulated expression and phosphorylation of hpttg proto-oncogene product by RAMOS-MORALES, F, DOMINGUEZ, A, ROMERO, F, LUNA, R, MULTON, M.-C, PINTOR-TORO, J. A, TORTOLERO, M

“…We recently isolated a cDNA for hpttg, the human homolog of rat pituitary tumor transforming gene. Now we have analysed the expression of hpttg as a function…”
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