Search Results - "Tortelli, Tharcísio Citrângulo"

STAT3 contributes to cisplatin resistance, modulating EMT markers, and the mTOR signaling in lung adenocarcinoma by Morelli, Ana Paula, Tortelli, Tharcísio Citrângulo, Mancini, Mariana Camargo Silva, Pavan, Isadora Carolina Betim, Silva, Luiz Guilherme Salvino, Severino, Matheus Brandemarte, Granato, Daniela Campos, Pestana, Nathalie Fortes, Ponte, Luis Gustavo Saboia, Peruca, Guilherme Francisco, Pauletti, Bianca Alves, dos Santos, Daniel Francisco Guimarães, de Moura, Leandro Pereira, Bezerra, Rosângela Maria Neves, Leme, Adriana Franco Paes, Chammas, Roger, Simabuco, Fernando Moreira

“…•SILAC proteomics approach yielded important cisplatin resistance biomarkers in NSCLC.•Cisplatin resistance upregulated NER-based repair and downregulated mRNA…”
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Emerging targets for combination therapy in melanomas by Saito, Renata de Freitas, Tortelli, Tharcísio Citrângulo, Jacomassi, Mayara D’Auria, Otake, Andréia Hanada, Chammas, Roger

“…Cutaneous melanomas are often difficult to treat when diagnosed in advanced stages. Melanoma cells adapt to survive in extreme environmental conditions and are…”
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deltaXpress (ΔXpress): a tool for mapping differentially correlated genes using single-cell qPCR data by Murillo Carrasco, Alexis Germán, Furuya, Tatiane Katsue, Uno, Miyuki, Citrangulo Tortelli, Tharcisio, Chammas, Roger

“…High-throughput experiments provide deep insight into the molecular biology of different species, but more tools need to be developed to handle this type of…”
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Metformin impairs cisplatin resistance effects in A549 lung cancer cells through mTOR signaling and other metabolic pathways by Morelli, Ana Paula, Tortelli, Tharcisio Citrangulo, Jr, Pavan, Isadora Carolina Betim, Silva, Fernando Riback, Granato, Daniela Campos, Peruca, Guilherme Francisco, Pauletti, Bianca Alves, Domingues, Romenia Ramos, Bezerra, Rosangela Maria Neves, de Moura, Leandro Pereira, Leme, Adriana Franco Paes, Chammas, Roger, Simabuco, Fernando Moreira

“…Lung cancer is the leading cause of cancer-associated death worldwide and exhibits intrinsic and acquired therapeutic resistance to cisplatin (CIS). The…”
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Sulforaphane: An emergent anti-cancer stem cell agent by Coutinho, Leandro de Lima, Junior, Tharcísio Citrangulo Tortelli, Rangel, Maria Cristina

“…Cancer is a major public health concern worldwide responsible for high morbidity and mortality rates. Alternative therapies have been extensively investigated,…”
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Stochastic model of contact inhibition and the proliferation of melanoma in situ by Morais, Mauro César Cafundó, Stuhl, Izabella, Sabino, Alan U., Lautenschlager, Willian W., Queiroga, Alexandre S., Tortelli, Tharcisio Citrangulo, Chammas, Roger, Suhov, Yuri, Ramos, Alexandre F.

“…Contact inhibition is a central feature orchestrating cell proliferation in culture experiments; its loss is associated with malignant transformation and…”
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Abstract 5598: Interaction between BRAF inhibitor PLX-4720 and CDK inhibitors can sensitize melanoma cells with BRAF V600E mutation by Tortelli, Tharcísio Citrângulo, Chammas, Roger, Chellappan, Srikumar

“…BRAF V600E mutation happens in 60% of all melanomas cases and this mutation is responsible to poor prognosis of the disease. BRAF is part of the MAPK signaling…”
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Accumulation of prohibitin is a common cellular response to different stressing stimuli and protects melanoma cells from ER stress and chemotherapy-induced cell death by Tortelli, Junior, Tharcisio Citrangulo, de Godoy, Lyris Martins Franco, de Souza, Gustavo Antonio, Bonatto, Diego, Otake, Andreia Hanada, de Freitas Saito, Renata, Rosa, Jose Cesar, Greene, Lewis Joel, Chammas, Roger

“…Melanoma is responsible for most deaths among skin cancers and conventional and palliative care chemotherapy are limited due to the development of…”
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Role of galectin-3 in the elastic response of radial growth phase melanoma cancer cells by Herrera-Reinoza, Nataly, Tortelli Junior, Tharcisio Citrangulo, Teixeira, Fernanda de Sá, Chammas, Roger, Salvadori, Maria Cecília

“…Melanoma is originated from the malignant transformation of the melanocytes and is characterized by a high rate of invasion, the more serious stage…”
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Distinct pattern of one-carbon metabolism, a nutrient-sensitive pathway, in invasive breast cancer: A metabolomic study by Santos, Jéssica Reis, Waitzberg, Dan Linetzky, da Silva, Ismael Dale Cotrim Guerreiro, Junior, Tharcisio Citrangulo Tortelli, Barros, Luciana Rodrigues Carvalho, Canuto, Gisele André Baptista, Faccio, Andréa Tedesco, Yamaguchi, Lydia Fumiko, Kato, Massuo Jorge, Tavares, Marina Franco Maggi, Martinez, Ana Cristina, Logullo, Ângela Flavia, Torrinhas, Raquel Suzana M M, Ravacci, Graziela

“…Altered cell metabolism is a hallmark of cancer and critical for its development. Particularly, activation of one-carbon metabolism in tumor cells can sustain…”
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Docosahexaenoic Acid Modulates a HER2-Associated Lipogenic Phenotype, Induces Apoptosis, and Increases Trastuzumab Action in HER2-Overexpressing Breast Carcinoma Cells by Waitzberg, Dan Linetzky, Santos, Jéssica Reis, Torrinhas, Raquel Suzana M. M., Tortelli, Tharcisio Citrângulo, Brentani, Maria Mitzi, Ravacci, Graziela Rosa, Logullo, Angela Flávia

“…In breast cancer, lipid metabolic alterations have been recognized as potential oncogenic stimuli that may promote malignancy. To investigate whether the…”
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Combined p14ARF and Interferon-β Gene Transfer to the Human Melanoma Cell Line SK-MEL-147 Promotes Oncolysis and Immune Activation by Cerqueira, Otto Luiz Dutra, Clavijo-Salomon, Maria Alejandra, Cardoso, Elaine Cristina, Citrangulo Tortelli Junior, Tharcisio, Mendonça, Samir Andrade, Barbuto, José Alexandre M, Strauss, Bryan E

“…Immune evasion is an important cancer hallmark and the understanding of its mechanisms has generated successful therapeutic approaches. Induction of…”
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Abstract 5548: Indicators of immune activation upon p14ARF and interferon-beta gene transfer in a human melanoma cell line by Cerqueira, Otto Luiz, Salomon, Maria Alejandra, Cardoso, Elaine Cristina, Tortelli, Tharcisio Citrangulo, Strauss, Bryan Eric

“…Immunoevasion adopted by tumor cells is an important cancer hallmark and understanding of its mechanisms has generated promising therapeutic approaches. In…”
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Metformin-induced chemosensitization to cisplatin depends on P53 status and is inhibited by Jarid1b overexpression in non-small cell lung cancer cells by Tortelli, Tharcisio Citrangulo, Tamura, Rodrigo Esaki, de Souza Junqueira, Mara, da Silva Mororó, Janio, Bustos, Silvina Odete, Natalino, Renato Jose Mendonça, Russell, Shonagh, Désaubry, Laurent, Strauss, Bryan Eric, Chammas, Roger

“…Metformin has been tested as an anti-cancer therapy with potential to improve conventional chemotherapy. However, in some cases, metformin fails to sensitize…”
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Abstract A50: 7-Ketocholesterol loaded-phosphatidylserine liposome induces cell death, autophagy, and growth inhibition of melanoma and breast adenocarcinoma by Favero, Giovani Marino, Tortelli, Tharcisio Citrangulo, Fernandes, Daniel, Prestes, Ana Paula, Kmetiuk, Louise N.B., Otake, Andreia Hanada, Andrade, Luciana N.S., Faria, Daniele de Paula, Carneiro, Camila de Godoi, Garcez, Alexandre Teles, Marques, Fabio L.N., Chammas, Roger

“…Background: The exposure of phosphatidylserine (PS) is one of the first steps of programmed cell death. Phagocytosis on cancer microenvironment is well…”
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Abstract A67: Jarid1b protects from metformin-induced chemosensitization to cisplatin through p53 downregulation in NSCLC by Tortelli, Tharcisio Citrangulo, Tamura, Rodrigo Esaki, Tomitao, Michele Tatiana Pereira, Bustos, Silvina Odete, Saito, Renata de Freitas, Leandrini, Sarah Milani de Moraes, Jacomassi, Mayara D'Aurea, Ribeiro, Ulysses, Strauss, Bryan Erik, Chammas, Roger

“…Background: Instead of nontransformed cells, tumor cells use the glycolytic pathway as their main energetic source, even when oxygen is fully available…”
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