Search Results - "Tortella, Bartholomew J."

Traumatic Tricuspid Valve Rupture Presenting as Third-Degree Atrioventricular Block by Theodoropoulos, Ioannis, MD, Cheeyandira, Abhiman, MD, Tortella, Bartholomew J., MD, MTS, MBA, FACS, FCCM

“…Abstract Background Cardiac valve injury after blunt chest trauma is extremely rare, and the tricuspid valve is most commonly affected because of the anterior…”
Get full text

Real-world outcomes associated with standard half-life and extended half-life factor replacement products for treatment of haemophilia A and B by Chhabra, Amit, Spurden, Dean, Fogarty, Patrick F., Tortella, Bartholomew J., Rubinstein, Emily, Harris, Simon, Pleil, Andreas M., Mellor, Jennifer, de Courcy, Jonathan, Alvir, José

“…Standard-of-care treatment for haemophilia A or B is to maintain adequate coagulation factor levels through clotting factor administration. The current study…”
Get full text

Deviations from evidence-based clinical management guidelines increase mortality in critically injured trauma patients by Rice, Todd W, Morris, Stephen, Tortella, Bartholomew J, Wheeler, Arthur P, Christensen, Michael C

“…OBJECTIVES:The effect of treatment guidelines on clinical outcomes in general and specifically for trauma patients has not been well-studied. We hypothesized…”
Get full text

Real-World Analysis of Dispensed IUs of Coagulation Factor IX and Resultant Expenditures in Hemophilia B Patients Receiving Standard Half-Life Versus Extended Half-Life Products and Those Switching from Standard Half-Life to Extended Half-Life Products by Tortella, Bartholomew J, Alvir, José, McDonald, Margaret, Spurden, Dean, Fogarty, Patrick F, Chhabra, Amit, Pleil, Andreas M

“…Hemophilia B requires replacement therapy with factor IX (FIX) coagulation products to treat and prevent bleeding episodes. A recently introduced extended…”
Get full text

Once-weekly prophylaxis regimen of nonacog alfa in patients with hemophilia B: an analysis of timing of bleeding event onset by Tortella, Bartholomew J., Carr, Marcus E., Rendo, Pablo, Korth-Bradley, Joan, Smith, Lynne M., Kavakli, Kaan

“…In a pivotal, multicenter, open-label study, 25 patients aged 12–54 years with moderately severe/severe hemophilia B received on-demand nonacog alfa (6 months;…”
Get full text

Interrelationship between depression, anxiety, pain, and treatment adherence in hemophilia: results from a US cross-sectional survey by Witkop, Michelle L, Lambing, Angela, Nichols, Cynthia D, Munn, James E, Anderson, Terry L, Tortella, Bartholomew J

“…Depression, anxiety, pain, and treatment adherence have reciprocal effects not characterized extensively in hemophilia. This study explored the relationships…”
Get full text

Results of the CONTROL Trial: Efficacy and Safety of Recombinant Activated Factor VII in the Management of Refractory Traumatic Hemorrhage by Hauser, Carl J., Boffard, Kenneth, Dutton, Richard, Bernard, Gordon R., Croce, Martin A., Holcomb, John B., Leppaniemi, Ari, Parr, Michael, Vincent, Jean-Louis, Tortella, Bartholomew J., Dimsits, Jeannett, Bouillon, Bertil

“…BACKGROUND:Traumatic coagulopathy contributes to early death by exsanguination and late death in multiple organ failure. Recombinant Factor VIIa (rFVIIa,…”
Get full text

Adverse Events and Discontinuation Rates Associated with Sirolimus Treatment in Adult Renal Transplant Patients in Latin America vs Non–Latin American Countries by Rial, Maria del Carmen, Tedesco Silva, Helio, Pacheco-Silva, Alvaro, Cruz, José, Torres, Rodolfo, Tortella, Bartholomew J., Li, Huihua, Cornicelli, Pablo, Estevez, Carlos

“…Sirolimus is approved for prophylaxis of organ rejection following renal transplantation. Rates of treatment-emergent adverse events (TEAEs) leading to…”
Get full text

Patient, caregiver, and provider perceptions of pain and pain management in adolescents and young adults with bleeding disorders by Lambing, Angela, Nichols, Cynthia D., Munn, James E., Anderson, Terry L., Tortella, Bartholomew J., Witkop, Michelle L.

“…Introduction Recurrent bleeding and associated pain are critical components in the management of bleeding disorders, yet scant data describe perceptions of…”
Get full text

Emerging and future therapies for hemophilia by Carr, Marcus E, Tortella, Bartholomew J

“…The evolution of care in hemophilia is a remarkable story. Over the last 60 years, advances in protein purification, protein chemistry, donor screening, viral…”
Get full text

Excess mortality, length of stay, and costs associated with serious hemorrhage among trauma patients: findings from the National Trauma Data Bank by Boulanger, Luke, Joshi, Ashish V, Tortella, Bartholomew J, Menzin, Joseph, Caloyeras, John P, Russell, Mason W

“…Trauma is a serious injury or shock to the body from violence or crash and is an important and growing global health risk. Using 2000 to 2004 data from a…”
Get more information

Validation of a hand-held lactate device in determination of blood lactate in critically injured patients by Slomovitz, Brian M, Lavery, Robert F, Tortella, Bartholomew J, Siegel, John H, Bachl, Bonita L, Ciccone, Anthony

“…OBJECTIVESAdmission blood lactate is an accurate predictor of injury severity and mortality in trauma patients. The purpose of this study was to evaluate a…”
Get full text

Analysis of US Claims Real World Data of Hemophilia a & B Patients: Units Dispensed & Expenditures Associated with Utilization of and Switching from Standard to Extended Half-Life Factor Products by Tortella, Bartholomew J., Chhabra, Amit, Alvir, José, Rubinstein, Emily R., Young, Lisa J., Fogarty, Patrick F.

“…Background: Both standard half-life (SHL) and extended half-life (EHL) factor replacement products are used to treat patients with hemophilia A (hem-A) and B…”
Get full text

Once-weekly prophylaxis regimen of nonacog alfa in patients with hemophilia B: an analysis of timing of bleeding event onset by Tortella, Bartholomew J., Carr, Marcus E., Rendo, Pablo, Korth-Bradley, Joan, Smith, Lynne M., Kavakli, Kaan

“…In a pivotal, multicenter, open-label study, 25 patients aged 12–54 years with moderately severe/severe hemophilia B received on-demand nonacog alfa (6 months;…”
Get full text

Real World Data Analysis of Coagulation Factor IX Costs in Specific Patients with Hemophilia B Switching from Standard Half-Life to Extended Half-Life Products by Tortella, Bartholomew J., Fogarty, Patrick F., Alvir, José, McDonald, Margaret, Spurden, Dean, Pleil, Andreas M.

“…Introduction: Hemophilia B, an X-linked genetic disease characterized by low clotting factor IX (FIX) levels, leads to spontaneous and traumatic bleeding in…”
Get full text

BE EMPOWERED, a specialty pharmacy education program for hemophilia B patients, impacts adult joint bleeds and pediatric use of RICE by Blankenship, Crystal S, Tortella, Bartholomew J, Bruno, Marianna

“…Traditional education about hemophilia B in hemophilia treatment centers (HTCs) and episodic contact with HTCs limit the amount of education patients and their…”
Get full text

Recombinant Activated Factor VII Safety in Trauma Patients: Results From the CONTROL Trial by Dutton, Richard P., Parr, Michael, Tortella, Bartholomew J., Champion, Howard R., Bernard, Gordon R., Boffard, Kenneth, Bouillon, Bertil, Croce, Martin A., Dimsits, Jeannett, Holcomb, John B., Leppaniemi, Ari, Vincent, Jean-Louis, Hauser, Carl J.

“…BACKGROUND:Safety data on recombinant activated factor VII (rFVIIa, NovoSeven; Novo Nordisk A/S, Bagsværd, Denmark) in actively hemorrhaging trauma patients…”
Get full text

The utility of venous lactate to triage injured patients in the trauma center1 by Lavery, Robert F., Livingston, David H., Tortella, Bartholomew J., Sambol, Justin T., Slomovitz, Brian M., Siegel, John H.

Get full text

Prospective, Randomized Trial of Epinephrine, Metaproterenol, and Both in the Prehospital Treatment of Asthma in the Adult Patient by Quadrel, Mark, Lavery, Robert F, Jaker, Michael, Atkin, Suzanne, Tortella, Bartholomew J, Cody, Ronald P

“…Study objective: To compare the effectiveness and incidence of adverse reactions with three treatment regimens for asthma in adults in the prehospital setting…”
Get full text

The Direct Economic Burden of Blunt and Penetrating Trauma in a Managed Care Population by Davis, Keith L., Joshi, Ashish V., Tortella, Bartholomew J., Candrilli, Sean D.

“…BACKGROUND:Although the prevalence of trauma in the United States is high, data on the economic burden of this public health problem to third-party payors is…”
Get full text