Physical activity and cardiovascular risk factors in children: meta-analysis of randomized clinical trials

Physical activity and cardiovascular risk factors in children: meta-analysis of randomized clinical trials

Abstract Objective To assess the effects of physical activity interventions in preventing cardiovascular risk factors in childhood through a systematic review and meta-analysis of randomized clinical trials (RCTs). Methods A search of online databases (PubMed, EMBASE and Cochrane CENTRAL) was conduc...

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Bibliographic Details
Published in:Preventive medicine Vol. 69; pp. 54 - 62
Main Authors: Cesa, Claudia Ciceri, Sbruzzi, Graciele, Ribeiro, Rodrigo Antonini, Barbiero, Sandra Mari, de Oliveira Petkowicz, Rosemary, Eibel, Bruna, Machado, Natássia Bigolin, Marques, Renata das Virgens, Tortato, Gabriela, dos Santos, Tiago Jerônimo, Leiria, Carina, Schaan, Beatriz D'Agord, Pellanda, Lucia Campos
Format: Journal Article
Language:English
Published: Amsterdam Elsevier Inc 01-12-2014
Elsevier
Subjects:
Biological and medical sciences
Blood pressure
Blood Pressure - physiology
Body Mass Index
Cardiovascular Diseases - prevention & control
Child
Cholesterol - blood
Exercise
Exercise - physiology
General aspects
Humans
Internal Medicine
Lipids
Medical sciences
Metabolic diseases
Miscellaneous
Motor activity
Obesity
Prevention and actions
Public health. Hygiene
Public health. Hygiene-occupational medicine
Randomized Controlled Trials as Topic
Risk Factors
Triglycerides - blood
Obesity
Lipids
Blood pressure
Exercise
Child
Motor activity
Human
Physical exercise
Factor analysis
Evidence-based practice
Nutrition disorder
Activity
Cardiovascular disease
Evidence-based medicine
Metaanalysis
Randomization
Risk factor
Cardiovascular risk
Clinical trial
Arterial pressure
Hemodynamics
Nutritional status
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Summary:Abstract Objective To assess the effects of physical activity interventions in preventing cardiovascular risk factors in childhood through a systematic review and meta-analysis of randomized clinical trials (RCTs). Methods A search of online databases (PubMed, EMBASE and Cochrane CENTRAL) was conducted from inception until June 2013. RCTs enrolling children 6–12 years old conducted physical activity interventions longer than 6 months, assessing their effect on body mass index (BMI), systolic (SBP) and diastolic blood pressure (DBP), total cholesterol (TC) and triglycerides (TG) were included. Data analysis was performed using a random-effects model. Results Of 23.091 articles retrieved, 11 RCTs (10.748 subjects) were included. Physical activity interventions were not associated with reductions of BMI [− 0.03 kg/m2 (95%CI − 0.16, 0.13) I2 0%]. However, there was an association between the interventions and reduction of SBP [− 1.25 mmHg (95%CI − 2.47, − 0.02) I2 0%], DBP [− 1.34 mmHg (95%CI − 2.57, − 0.11) I2 43%] and TG [− 0.09 mmol/L (95%CI − 0.14, − 0.04) I2 0%], and increase of TC [0.14 mmol/L (95%CI 0.01, 0.27) I2 0%]. Conclusion As physical activity intervention programs lasting longer than 6 months are associated with reductions in blood pressure levels and triglycerides, they should be considered to be included in prevention programs for cardiovascular diseases in schoolchildren.
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ISSN:0091-7435
1096-0260
DOI:10.1016/j.ypmed.2014.08.014