Search Results - "Torsten Witte"

Autoimmunity and primary immunodeficiency: two sides of the same coin? by Schmidt, Reinhold E., Grimbacher, Bodo, Witte, Torsten

“…Key Points Immune dysregulation in many primary immunodeficiency syndromes leads to autoimmune disease manifestations Mutations in various genes can lead to…”
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The link between rheumatic disorders and inborn errors of immunity by Sogkas, Georgios, Witte, Torsten

“…Inborn errors of immunity (IEIs) are immunological disorders characterized by variable susceptibility to infections, immune dysregulation and/or malignancies,…”
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Perceived versus proven SARS-CoV-2-specific immune responses in health-care professionals by Behrens, Georg M. N., Cossmann, Anne, Stankov, Metodi V., Witte, Torsten, Ernst, Diana, Happle, Christine, Jablonka, Alexandra

“…There have been concerns about high rates of thus far undiagnosed SARS-CoV-2 infections in the health-care system. The COVID-19 Contact (CoCo) Study follows…”
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Cellular and molecular mechanisms breaking immune tolerance in inborn errors of immunity by Sogkas, Georgios, Atschekzei, Faranaz, Adriawan, Ignatius Ryan, Dubrowinskaja, Natalia, Witte, Torsten, Schmidt, Reinhold Ernst

“…In addition to susceptibility to infections, conventional primary immunodeficiency disorders (PIDs) and inborn errors of immunity (IEI) can cause immune…”
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Natural antibodies and CRP drive anaphylatoxin production by urate crystals by Wessig, Anne Kathrin, Hoffmeister, Leonie, Klingberg, Annika, Alberts, Anika, Pich, Andreas, Brand, Korbinian, Witte, Torsten, Neumann, Konstantin

“…In gout, crystallization of uric acid in the form of monosodium urate (MSU) leads to a painful inflammatory response. MSU crystals induce inflammation by…”
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Resting state fMRI reveals increased subthalamic nucleus–motor cortex connectivity in Parkinson's disease by Baudrexel, Simon, Witte, Torsten, Seifried, Carola, von Wegner, Frederic, Beissner, Florian, Klein, Johannes C., Steinmetz, Helmuth, Deichmann, Ralf, Roeper, Jochen, Hilker, Rüdiger

“…Parkinson's disease (PD) is associated with abnormal hypersynchronicity in basal ganglia-thalamo-cortical loops. The clinical effectiveness of subthalamic…”
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CIDP associated with Sjögren’s syndrome by Seeliger, Tabea, Gingele, Stefan, Bönig, Lena, Konen, Franz Felix, Körner, Sonja, Prenzler, Nils, Thiele, Thea, Ernst, Diana, Witte, Torsten, Stangel, Martin, Skripuletz, Thomas

“…Background This study addresses the challenging characterisation and differentiation of CIDP versus CIDP in association with Sjögren’s syndrome to facilitate…”
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Neuro-Sjögren: Peripheral Neuropathy With Limb Weakness in Sjögren's Syndrome by Seeliger, Tabea, Prenzler, Nils K, Gingele, Stefan, Seeliger, Benjamin, Körner, Sonja, Thiele, Thea, Bönig, Lena, Sühs, Kurt-Wolfram, Witte, Torsten, Stangel, Martin, Skripuletz, Thomas

“…Sjögren's syndrome is a heterogeneous inflammatory disorder frequently involving peripheral nerves with a wide spectrum of sensory modalities and distribution…”
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C-reactive protein (CRP) recognizes uric acid crystals and recruits proteases C1 and MASP1 by Alberts, Anika, Klingberg, Annika, Wessig, Anne Kathrin, Combes, Christèle, Witte, Torsten, Brand, Korbinian, Pich, Andreas, Neumann, Konstantin

“…Gout is caused by crystallization of uric acid in the form of monosodium urate (MSU) crystals, which induce a sterile inflammatory response that is hardly…”
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The EUROclass trial: defining subgroups in common variable immunodeficiency by Wehr, Claudia, Kivioja, Teemu, Schmitt, Christian, Ferry, Berne, Witte, Torsten, Eren, Efrem, Vlkova, Marcela, Hernandez, Manuel, Detkova, Drahomira, Bos, Philip R., Poerksen, Gonke, von Bernuth, Horst, Baumann, Ulrich, Goldacker, Sigune, Gutenberger, Sylvia, Schlesier, Michael, Bergeron-van der Cruyssen, Florence, Le Garff, Magali, Debré, Patrice, Jacobs, Roland, Jones, John, Bateman, Elizabeth, Litzman, Jiri, van Hagen, P. Martin, Plebani, Alessandro, Schmidt, Reinhold E., Thon, Vojtech, Quinti, Isabella, Espanol, Teresa, Webster, A. David, Chapel, Helen, Vihinen, Mauno, Oksenhendler, Eric, Peter, Hans Hartmut, Warnatz, Klaus

“…The heterogeneity of common variable immunodeficiency (CVID) calls for a classification addressing pathogenic mechanisms as well as clinical relevance. This…”
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Common Variable Immunodeficiency-Associated Cancers: The Role of Clinical Phenotypes, Immunological and Genetic Factors by Bruns, Luzia, Panagiota, Victoria, von Hardenberg, Sandra, Schmidt, Gunnar, Adriawan, Ignatius Ryan, Sogka, Eleni, Hirsch, Stefanie, Ahrenstorf, Gerrit, Witte, Torsten, Schmidt, Reinhold Ernst, Atschekzei, Faranaz, Sogkas, Georgios

“…The aim of this study was to investigate the prevalence of cancer and associating clinical, immunological, and genetic factors in a German cohort of patients…”
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Improved Prognosis of Infection With Mycobacterium Genavense in Immune-Compromized HIV Patients After Introduction of Combined Antiretroviral Therapy by Ahrenstorf, Gerrit, Jablonka, Alexandra, Ernst, Diana, Bange, Franz-Christoph, Heiken, Hans, Witte, Torsten, Schmidt, Reinhold E., Stoll, Matthias

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The Persisting Significance of Oligoclonal Bands in the Dawning Era of Kappa Free Light Chains for the Diagnosis of Multiple Sclerosis by Schwenkenbecher, Philipp, Konen, Franz Felix, Wurster, Ulrich, Jendretzky, Konstantin Fritz, Gingele, Stefan, Sühs, Kurt-Wolfram, Pul, Refik, Witte, Torsten, Stangel, Martin, Skripuletz, Thomas

“…The latest revision of the McDonald criteria of 2017 considers the evidence of an intrathecal immunoglobulin (IgG) synthesis as a diagnostic criterion for…”
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Corrigendum: Vulnerability to meningococcal disease in immunodeficiency due to a novel pathogenic missense variant in NFKB1 by Anim, Manfred, Sogkas, Georgios, Schmidt, Gunnar, Dubrowinskaja, Natalia, Witte, Torsten, Schmidt, Reinhold Ernst, Atschekzei, Faranaz

“…[This corrects the article DOI: 10.3389/fimmu.2021.767188.]…”
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Implications of COVID-19 Outbreak on Immune Therapies in Multiple Sclerosis Patients-Lessons Learned From SARS and MERS by Möhn, Nora, Pul, Refik, Kleinschnitz, Christoph, Prüss, Harald, Witte, Torsten, Stangel, Martin, Skripuletz, Thomas

“…Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic keeps the world in suspense. In addition to the fundamental challenges for the health…”
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Comment on: Rituximab therapy for Takayasu arteritis: a seven patients experience and a review of the literature by Nakagomi, Daiki, Kronbichler, Andreas, Witte, Torsten, Mohammad, Aladdin J, Jayne, David R W

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Anti-CD74 antibodies have no diagnostic value in early axial spondyloarthritis: data from the spondyloarthritis caught early (SPACE) cohort by de Winter, Janneke J, van de Sande, Marleen G, Baerlecken, Niklas, Berg, Inger, Ramonda, Roberta, van der Heijde, Désirée, van Gaalen, Floris A, Witte, Torsten, Baeten, Dominique L

“…Anti-CD74 IgG antibodies are reported to be elevated in patients with axial spondyloarthritis (axSpA). This study assessed the diagnostic value of anti-CD74…”
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Vulnerability to Meningococcal Disease in Immunodeficiency Due to a Novel Pathogenic Missense Variant in NFKB1 by Anim, Manfred, Sogkas, Georgios, Schmidt, Gunnar, Dubrowinskaja, Natalia, Witte, Torsten, Schmidt, Reinhold Ernst, Atschekzei, Faranaz

“…NF-κB1 deficiency is suggested to be the most common cause of common variable immunodeficiency (CVID). encodes for the p105 precursor protein of NF-κB1, which…”
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JAK inhibitors to treat STAT3 gain-of-function: a single-center report and literature review by Atschekzei, Faranaz, Traidl, Stephan, Carlens, Julia, Schütz, Katharina, von Hardenberg, Sandra, Elsayed, Abdulwahab, Ernst, Diana, Risser, Linus, Thiele, Thea, Graalmann, Theresa, Raab, Juliana, Baumann, Ulrich, Witte, Torsten, Sogkas, Georgios

“…The signal transducer and activator of transcription 3 (STAT3) gain-of-function (GOF) syndrome (STAT3-GOF) is an inborn error of immunity (IEI) characterized…”
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Use of Complementary and Alternative Medicine in Patients with Primary Immunodeficiency: a Multicentric Analysis of 101 Patients by Harasim, Anna S., Krone, Manuel, Tony, Hans-Peter, Gawlik, Micha, Witte, Torsten, Joos, Stefanie, Gernert, Michael, Schmalzing, Marc, Morbach, Henner, Schwaneck, Eva C.

“…The term complementary and alternative medicine (CAM) describes a broad spectrum of health care practices that are not an integral part of the conventional…”
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