Search Results - "Torsten, P."
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Gut Microbiota as a Trigger for Metabolic Inflammation in Obesity and Type 2 Diabetes
Published in Frontiers in immunology (16-10-2020)“…The gut microbiota has been linked to the development of obesity and type 2 diabetes (T2D). The underlying mechanisms as to how intestinal microbiota may…”
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Gut virome profiling identifies a widespread bacteriophage family associated with metabolic syndrome
Published in Nature communications (23-06-2022)“…There is significant interest in altering the course of cardiometabolic disease development via gut microbiomes. Nevertheless, the highly abundant phage…”
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Distinct fecal and oral microbiota composition in human type 1 diabetes, an observational study
Published in PloS one (06-12-2017)“…Environmental factors driving the development of type 1 diabetes (T1D) are still largely unknown. Both animal and human studies have shown an association…”
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Phage-microbe dynamics after sterile faecal filtrate transplantation in individuals with metabolic syndrome: a double-blind, randomised, placebo-controlled clinical trial assessing efficacy and safety
Published in Nature communications (12-09-2023)“…Bacteriophages (phages) are bacterial viruses that have been shown to shape microbial communities. Previous studies have shown that faecal virome…”
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Transcatheter Aortic Valve Replacement 2016: A Modern-Day "Through the Looking-Glass" Adventure
Published in Journal of the American College of Cardiology (29-03-2016)“…Transcatheter aortic valve replacement (TAVR) has become a safe and effective therapy for patients with severe aortic stenosis (AS). In recent trials, the…”
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Quantity and Location of Aortic Valve Complex Calcification Predicts Severity and Location of Paravalvular Regurgitation and Frequency of Post-Dilation After Balloon-Expandable Transcatheter Aortic Valve Replacement
Published in JACC. Cardiovascular interventions (01-08-2014)“…Abstract Objectives This study sought to determine the impact of quantity and location of aortic valve calcification (AVC) on paravalvular regurgitation (PVR)…”
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Weighing Transcatheter Aortic Valve Replacement vs Surgical Aortic Valve Replacement for Native Aortic Regurgitation
Published in The Annals of thoracic surgery (01-04-2023)Get full text
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Zero-Contrast Left Atrial Appendage Occlusion Using a Hybrid Echocardiography-Fluoroscopy Technique Without Iodinated Contrast
Published in The American journal of cardiology (01-07-2023)“…Contrast exposure during left atrial appendage occlusion may be harmful in those with chronic kidney disease or allergy. This single-center registry (n = 31)…”
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Sphingosine-1-Phosphate Receptor Agonist Fingolimod Increases Myocardial Salvage and Decreases Adverse Postinfarction Left Ventricular Remodeling in a Porcine Model of Ischemia/Reperfusion
Published in Circulation (New York, N.Y.) (08-03-2016)“…BACKGROUND—Fingolimod, a sphingosine-1-phosphate receptor agonist, is used for the treatment of multiple sclerosis and exerts antiapoptotic properties. We…”
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Glucose-mediated insulin secretion is improved in FHL2-deficient mice and elevated FHL2 expression in humans is associated with type 2 diabetes
Published in Diabetologia (01-10-2022)“…Aims/hypothesis The general population is ageing, involving an enhanced incidence of chronic diseases such as type 2 diabetes. With ageing, DNA methylation of…”
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Gut microbe-host interactions in post-COVID syndrome: a debilitating or restorative partnership?
Published in Gut microbes (01-01-2024)“…Post-COVID syndrome (PCS) patients have reported a wide range of symptoms, including fatigue, shortness of breath, and diarrhea. Particularly, the presence of…”
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Transcatheter transseptal treatment of patients with severe mitral regurgitation using an atrial fixation mitral valve replacement technology
Published in Cardiovascular revascularization medicine (01-01-2024)“…Mitral regurgitation (MR) is the most common valvular heart disease worldwide with a 5-year mortality rate of 50 % with medical therapy alone. Several…”
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Optimizing Cardiac CT Protocols for Comprehensive Acquisition Prior to Percutaneous MV and TV Repair/Replacement
Published in JACC. Cardiovascular imaging (01-03-2020)“…Clinical trials of transcatheter mitral valve and tricuspid valve repair and replacement devices have begun in earnest, with the ultimate goal of providing…”
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Early Single-Site Experience With Transcatheter Tricuspid Valve Replacement
Published in JACC. Cardiovascular imaging (01-03-2019)“…This study presents a single-site experience of 5 patients with severe tricuspid regurgitation (TR) who underwent implantation of a novel transcatheter…”
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Effect of Fecal Microbiota Transplantation Combined With Mediterranean Diet on Insulin Sensitivity in Subjects With Metabolic Syndrome
Published in Frontiers in microbiology (10-06-2021)“…Recent studies demonstrate that a Mediterranean diet has beneficial metabolic effects in metabolic syndrome subjects. Since we have shown that fecal microbiota…”
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Faecal Microbiota transplantation affects liver DNA methylation in Non-alcoholic fatty liver disease: a multi-omics approach
Published in Gut microbes (31-12-2023)“…Individuals with nonalcoholic fatty liver disease (NAFLD) have an altered gut microbiota composition. Moreover, hepatic DNA methylation may be altered in the…”
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Regulation of Islet Hormone Release and Gastric Emptying by Endogenous Glucagon-Like Peptide 1 after Glucose Ingestion
Published in The journal of clinical endocrinology and metabolism (01-12-2008)“…Background: Exogenous administration of glucagon-like peptide (GLP)-1 improves glucose tolerance by stimulation of insulin secretion, inhibition of glucagon…”
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Transcatheter aortic valve implantation in patients with high-risk symptomatic native aortic regurgitation (ALIGN-AR): a prospective, multicentre, single-arm study
Published in The Lancet (British edition) (13-04-2024)“…Surgery remains the only recommended intervention for patients with native aortic regurgitation. A transcatheter therapy to treat patients at high risk for…”
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Impact of the COVID‐19 pandemic on interventional cardiology fellowship training in the New York metropolitan area: A perspective from the United States epicenter
Published in Catheterization and cardiovascular interventions (01-02-2021)“…Background The healthcare burden posed by the coronavirus disease 2019 (COVID‐19) pandemic in the New York Metropolitan area has necessitated the postponement…”
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Low and elevated B-type natriuretic peptide levels are associated with increased mortality in patients with preserved ejection fraction undergoing transcatheter aortic valve replacement: an analysis of the PARTNER II trial and registry
Published in European heart journal (21-02-2020)“…Abstract Aims B-type natriuretic peptide (BNP) is a cardiac neurohormone that is secreted in response to ventricular volume expansion and pressure overload…”
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