Search Results - "Torres, Néstor V."

Mapping the transcriptomic changes of endothelial compartment in human hippocampus across aging and mild cognitive impairment by Guebel, Daniel V, Torres, Néstor V, Acebes, Ángel

“…Compromise of the vascular system has important consequences on cognitive abilities and neurodegeneration. The identification of the main molecular signatures…”
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A new academic performance indicator for the first term of first‐year science degrees students at La Laguna University: a predictive model by Dorta‐Guerra, Roberto, Marrero, Isabel, Abdul‐Jalbar, Beatriz, Trujillo‐González, Rodrigo, Torres, Néstor V.

“…Academic performance during the first year of university is correlated with future academic success, and is considered to be a determining factor in the…”
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Modeling of leishmaniasis infection dynamics: novel application to the design of effective therapies by Länger, Bettina M, Pou-Barreto, Cristina, González-Alcón, Carlos, Valladares, Basilio, Wimmer, Bettina, Torres, Néstor V

“…The WHO considers leishmaniasis as one of the six most important tropical diseases worldwide. It is caused by parasites of the genus Leishmania that are passed…”
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Model based optimization of feeding regimens in aquaculture: Application to the improvement of Octopus vulgaris viability in captivity by Hormiga, José A., Almansa, Eduardo, Sykes, António V., Torres, Néstor V.

“…The culture of common octopus ( Octopus vulgaris), one important candidate to the aquaculture diversification, faces significant difficulties, mainly related…”
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Modelling and analysis of central metabolism operating regulatory interactions in salt stress conditions in a L-carnitine overproducing E. coli strain by Santos, Guido, Hormiga, José A, Arense, Paula, Cánovas, Manuel, Torres, Néstor V

“…Based on experimental data from E. coli cultures, we have devised a mathematical model in the GMA-power law formalism that describes the central and…”
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Analysis of the Escherichia coli response to glycerol pulse in continuous, high-cell density culture using a multivariate approach by Guebel, Daniel V, Cánovas, Manuel, Torres, Néstor V

“…Pulse experiments in continuous-culture are a valuable tool in microbial physiology research. However, inferences become difficult when the cell response is…”
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New targets for drug discovery against malaria by Santos, Guido, Torres, Néstor V

“…A mathematical model which predicts the intraerythrocytic stages of Plasmodium falciparum infection was developed using data from malaria-infected mice…”
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Sexual Dimorphism and Aging in the Human Hyppocampus: Identification, Validation, and Impact of Differentially Expressed Genes by Factorial Microarray and Network Analysis by Guebel, Daniel V, Torres, Néstor V

“…In the brain of elderly-healthy individuals, the effects of sexual dimorphism and those due to normal aging appear overlapped. Discrimination of these two…”
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The (Mathematical) Modeling Process in Biosciences by Torres, Nestor V, Santos, Guido

“…In this communication, we introduce a general framework and discussion on the role of models and the modeling process in the field of biosciences. The…”
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Lipid Raft Size and Lipid Mobility in Non-raft Domains Increase during Aging and Are Exacerbated in APP/PS1 Mice Model of Alzheimer's Disease. Predictions from an Agent-Based Mathematical Model by Santos, Guido, Díaz, Mario, Torres, Néstor V

“…A connection between lipid rafts and Alzheimer's disease has been studied during the last decades. Mathematical modeling approaches have recently been used to…”
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Influence of Glucose Availability and CRP Acetylation on the Genome-Wide Transcriptional Response of Escherichia coli : Assessment by an Optimized Factorial Microarray Analysis by Guebel, Daniel V, Torres, Néstor V

“…While in eukaryotes acetylation/deacetylation regulation exerts multiple pleiotropic effects, in it seems to be more limited and less known. Hence, we aimed to…”
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Quantitative analysis of the processes and signaling events involved in early HIV-1 infection of T cells by Santos, Guido, Valenzuela-Fernández, Agustín, Torres, Néstor V

“…Lymphocyte invasion by HIV-1 is a complex, highly regulated process involving many different types of molecules that is prompted by the virus's association…”
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Q-GDEMAR: a general method for the identification of differentially expressed genes in microarrays with unbalanced groups by Guebel, Daniel V, Perera-Alberto, Montserrat, Torres, Néstor V

“…Microarray analysis is a powerful tool to simultaneously determine the pattern of transcription of large amounts of genes. For data post-processing distinct…”
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Integrated nonlinear optimization of bioprocesses via linear programming by Vera, Julio, Torres, Néstor V., Moles, Carmen G., Banga, Julio

“…The problem of integrated design and control of bioprocess plants is considered. A previously presented optimization approach for biochemical systems based on…”
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Pathway Analysis and Optimization in Metabolic Engineering by Torres, Néstor V., Voit, Eberhard O.

“…Facility in the targeted manipulation of the genetic and metabolic composition of organisms, combined with unprecedented computational power, is forging a…”
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Detection of potential enzyme targets by metabolic modelling and optimization: Application to a simple enzymopathy by Vera, Julio, Curto, Raul, Cascante, Marta, Torres, Néstor V.

“…Motivation: A very promising approach in drug discovery involves the integration of available biomedical data through mathematical modelling and data mining…”
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Introducing Systems Biology to Bioscience Students through Mathematical Modelling. A Practical Module by Torres, Nestor V

“…Systems Biology, one of the current approaches to the understanding of living things, aims to understand the behaviour of living systems through the creation…”
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Model identification in presence of incomplete information by generalized principal component analysis: Application to the common and differential responses of Escherichia coli to multiple pulse perturbations in continuous, high-biomass density culture by Guebel, Daniel V., Cánovas, Manuel, Torres, Néstor V.

“…In a previous report we described a multivariate approach to discriminate between the different response mechanisms operating in Escherichia coli when a…”
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Multicriteria optimization of biochemical systems by linear programming: Application to production of ethanol by Saccharomyces cerevisiae by Vera, Julio, De Atauri, Pedro, Cascante, Marta, Torres, Néstor V.

“…In this study we present a method for simultaneous optimization of several metabolic responses of biochemical pathways. The method, based on the use of the…”
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A computer model of oxygen dynamics in human colon mucosa: Implications in normal physiology and early tumor development by Guebel, Daniel V., Torres, Néstor V.

“…Based on the geometry of the colon mucosa, we built a model to compute the oxygen supply, the oxygen diffusion across the interstitial matrix, and the oxygen…”
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