Search Results - "Torres, Karen E.O"
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Deguelin inhibits growth of breast cancer cells by modulating the expression of key members of the Wnt signaling pathway
Published in Cancer prevention research (Philadelphia, Pa.) (01-11-2009)“…An emphasis in early detection and more effective treatments has decreased the mortality rate of breast cancer. Despite this decrease, breast cancer continues…”
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Transcript Profiling of Individual Twin Blastomeres Derived by Splitting Two-Cell Stage Murine Embryos
Published in Biology of reproduction (01-03-2011)“…In invertebrates and amphibians, informational macromolecules in egg cytoplasm are organized to provide direction to the formation of embryonic lineages, but…”
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Transcript Profiling of Individual Twin Blastomeres Derived by Splitting Two-Cell Stage Murine Embryos1
Published in Biology of reproduction (01-03-2011)“…In invertebrates and amphibians, informational macromolecules in egg cytoplasm are organized to provide direction to the formation of embryonic lineages, but…”
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4
Protection against cellular stress by 25‐hydroxyvitamin D 3 in breast epithelial cells
Published in Journal of cellular biochemistry (15-08-2010)“…Abstract 25‐Hydroxyvitamin D 3 (25(OH)D 3 ) is a prohormone and a major vitamin D metabolite. The discovery of (25(OH)D 3 ) 1α‐hydroxylase in many vitamin D…”
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5
Traumatic brain injury induces long-lasting changes in immune and regenerative signaling
Published in PloS one (03-04-2019)“…There are no existing treatments for the long-term degenerative effects of traumatic brain injury (TBI). This is due, in part, to our limited understanding of…”
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Comparison of Gene Expression by Sheep and Human Blood Stimulated with the TLR4 Agonists Lipopolysaccharide and Monophosphoryl Lipid A
Published in PloS one (07-12-2015)“…Animal models that mimic human biology are important for successful translation of basic science discoveries into the clinical practice. Recent studies in…”
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Evidence linking microRNA suppression of essential prosurvival genes with hippocampal cell death after traumatic brain injury
Published in Scientific reports (27-07-2017)“…The underlying molecular mechanisms of how dysregulated microRNAs (miRNAs) cause neurodegeneration after traumatic brain injury (TBI) remain elusive. Here we…”
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MicroRNA profiling identifies a novel compound with antidepressant properties
Published in PloS one (23-08-2019)“…Patients with traumatic brain injury (TBI) are frequently diagnosed with depression. Together, these two leading causes of death and disability significantly…”
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Differential roles of ERα and ERβ in normal and neoplastic development in the mouse mammary gland
Published in PloS one (18-11-2014)“…The present experiments were performed to determine the roles of estrogen receptors α and β (ERα and ERβ) in normal and neoplastic development in the mouse…”
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Overexpression of lipocalins and pro-inflammatory chemokines and altered methylation of PTGS2 and APC2 in oral squamous cell carcinomas induced in rats by 4-nitroquinoline-1-oxide
Published in PloS one (30-01-2015)“…Oral squamous cell carcinomas (OSCC) induced in F344 rats by 4-nitroquinoline-1-oxide (4-NQO) demonstrate considerable phenotypic similarity to human oral…”
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Effects of AAV-mediated knockdown of nNOS and GPx-1 gene expression in rat hippocampus after traumatic brain injury
Published in PloS one (10-10-2017)“…Virally mediated RNA interference (RNAi) to knock down injury-induced genes could improve functional outcome after traumatic brain injury (TBI); however,…”
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Abstract 967: Serine proteases as targets for prostate cancer prevention: Identification by analysis of differential gene expression in rodent and human prostate cancers
Published in Cancer research (Chicago, Ill.) (15-04-2010)“…Abstract Patterns of gene expression in normal and neoplastic prostate tissues from rats and humans were compared to identify novel molecular targets for…”
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Protection against cellular stress by 25-hydroxyvitamin D3 in breast epithelial cells
Published in Journal of cellular biochemistry (15-08-2010)“…25‐Hydroxyvitamin D3 (25(OH)D3) is a prohormone and a major vitamin D metabolite. The discovery of (25(OH)D3) 1α‐hydroxylase in many vitamin D target organs…”
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14
Subchronic Toxicity and Toxicogenomic Evaluation of Tamoxifen Citrate + Bexarotene in Female Rats
Published in Toxicological sciences (01-10-2007)“…Tamoxifen (TAM) is a nonsteroidal antiestrogen that prevents estrogen receptor–positive breast cancer in rodents and humans. Bexarotene (BEX), a selective…”
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