Search Results - "Torres, Gonzalo E."

The dopamine transporter proteome by Torres, Gonzalo E.

“…Dopamine (DA) uptake through the neuronal plasma membrane DA transporter (DAT) is essential for the maintenance of normal DA homeostasis in the brain. The…”
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A Biochemical and Functional Protein Complex Involving Dopamine Synthesis and Transport into Synaptic Vesicles by Cartier, Etienne A., Parra, Leonardo A., Baust, Tracy B., Quiroz, Marisol, Salazar, Gloria, Faundez, Victor, Egaña, Loreto, Torres, Gonzalo E.

“…Synaptic transmission depends on neurotransmitter pools stored within vesicles that undergo regulated exocytosis. In the brain, the vesicular monoamine…”
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Collective and Coordinated Conformational Changes Determine Agonism or Antagonism at the Human Trace Amine-Associated Receptor 1 by Robles, Agustín I., Dinamarca-Villarroel, Luis, Torres, Gonzalo E., Fierro, Angélica

“…The human trace amine-associated receptor (hTAAR1), a G protein-coupled receptor, has been postulated as a new target in the treatment of neuropsychiatric…”
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Identification of Critical Residues in the Carboxy Terminus of the Dopamine Transporter Involved in the G Protein βγ-Induced Dopamine Efflux by Pino, José A, Nuñez-Vivanco, Gabriel, Hidalgo, Gabriela, Reyes Parada, Miguel, Khoshbouei, Habibeh, Torres, Gonzalo E

“…The dopamine transporter (DAT) plays a crucial role in the regulation of brain dopamine (DA) homeostasis through the re-uptake of DA back into the presynaptic…”
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Programming of Dopaminergic Neurons by Early Exposure to Sex Hormones: Effects on Morphine-Induced Accumbens Dopamine Release, Reward, and Locomotor Behavior in Male and Female Rats by Velásquez, Victoria B, Zamorano, Gabriel A, Martínez-Pinto, Jonathan, Bonansco, Christian, Jara, Pablo, Torres, Gonzalo E, Renard, Georgina M, Sotomayor-Zárate, Ramón

“…Neonatal programming with sex hormones produces long-term functional changes in various tissues, including the brain. Previously, we demonstrated a higher…”
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Identification of PSD-95 as a Regulator of Dopamine-Mediated Synaptic and Behavioral Plasticity by Yao, Wei-Dong, Gainetdinov, Raul R, Arbuckle, Margaret I, Sotnikova, Tatyana D, Cyr, Michel, Beaulieu, Jean-Martin, Torres, Gonzalo E, Grant, Seth G.N, Caron, Marc G

“…To identify the molecular mechanisms underlying psychostimulant-elicited plasticity in the brain reward system, we undertook a phenotype-driven approach using…”
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Inhibition of dopamine transporter activity by G protein βγ subunits by Garcia-Olivares, Jennie, Torres-Salazar, Delany, Owens, William A, Baust, Tracy, Siderovski, David P, Amara, Susan G, Zhu, Jun, Daws, Lynette C, Torres, Gonzalo E

“…Uptake through the Dopamine Transporter (DAT) is the primary mechanism of terminating dopamine signaling within the brain, thus playing an essential role in…”
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Alterations of the gut microbiota with antibiotics protects dopamine neuron loss and improve motor deficits in a pharmacological rodent model of Parkinson's disease by Koutzoumis, Dimitri N., Vergara, Macarena, Pino, Jose, Buddendorff, Julia, Khoshbouei, Habibeh, Mandel, Ronald J., Torres, Gonzalo E.

“…Parkinson's disease (PD) is a debilitating condition resulting in motor and non-motor symptoms affecting approximately 10 million people worldwide. Currently,…”
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Functional Interaction between Monoamine Plasma Membrane Transporters and the Synaptic PDZ Domain–Containing Protein PICK1 by Torres, Gonzalo E, Yao, Wei-Dong, Mohn, Amy R, Quan, Hui, Kim, Kyeong-Man, Levey, Allan I, Staudinger, Jeff, Caron, Marc G

“…PDZ domain–containing proteins play an important role in the targeting and localization of synaptic membrane proteins. Here, we report an interaction between…”
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The zebrafish homologue of the human DYT1 dystonia gene is widely expressed in CNS neurons but non-essential for early motor system development by Sager, Jonathan J, Torres, Gonzalo E, Burton, Edward A

“…DYT1 dystonia is caused by mutation of the TOR1A gene, resulting in the loss of a single glutamic acid residue near the carboxyl terminal of TorsinA. The…”
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The orphan transporter Rxt1/NTT4 (SLC6A17) functions as a synaptic vesicle amino acid transporter selective for proline, glycine, leucine, and alanine by Parra, Leonardo A, Baust, Tracy, El Mestikawy, Salah, Quiroz, Marisol, Hoffman, Beth, Haflett, Jack M, Yao, Jeffrey K, Torres, Gonzalo E

“…Rxt1/NTT4 (SLC6A17) belongs to a gene family of "orphan transporters" whose substrates and consequently functions remain unidentified. Although Rxt1/NTT4 was…”
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Early-life exposure to sex hormones promotes voluntary ethanol intake in adulthood. A vulnerability factor to drug addiction by Venegas, Francisca C., Rosas, Daniela, Delgado, Nicol, Estay-Olmos, Camila, Iturriaga-Vásquez, Patricio, Rivera-Meza, Mario, Torres, Gonzalo E., Renard, Georgina M., Sotomayor-Zárate, Ramón

“…While there is extensive research on alcohol dependence, the factors that make an individual vulnerable to developing alcoholism haven't been explored much. In…”
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Glutamate and monoamine transporters: new visions of form and function by Torres, Gonzalo E, Amara, Susan G

“…Neurotransmitters are rapidly removed from the extracellular space primarily through the actions of plasma membrane transporters. This uptake process is not…”
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Adolescent Behavior and Dopamine Availability Are Uniquely Sensitive to Dietary Omega-3 Fatty Acid Deficiency by Bondi, Corina O, Taha, Ameer Y, Tock, Jody L, Totah, Nelson K.B, Cheon, Yewon, Torres, Gonzalo E, Rapoport, Stanley I, Moghaddam, Bita

“…Background Understanding the nature of environmental factors that contribute to behavioral health is critical for successful prevention strategies in…”
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Monoamine Transporters: Vulnerable and Vital Doorkeepers by Lin, Zhicheng, Canales, Juan J, Björgvinsson, Thröstur, Thomsen, Morgane, Qu, Hong, Liu, Qing-Rong, Torres, Gonzalo E, Caine, S Barak

“…Transporters of dopamine, serotonin, and norepinephrine have been empirically used as medication targets for several mental illnesses in the last decades…”
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Proteins Interacting with Monoamine Transporters: Current State and Future Challenges by Sager, Jonathan J, Torres, Gonzalo E

“…Plasma membrane and vesicular transporters for the biogenic amines, dopamine, norepinephrine, and serotonin, represent a group of proteins that play a crucial…”
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Betel quid: New insights into an ancient addiction by Stokes, Clare, Pino, Jose A., Hagan, D. Walker, Torres, Gonzalo E., Phelps, Edward A., Horenstein, Nicole A., Papke, Roger L.

“…The use of areca nuts (areca) in the form of betel quids constitutes the fourth most common addiction in the world, associated with high risk for oral disease…”
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Neonatal programming with testosterone propionate reduces dopamine transporter expression in nucleus accumbens and methylphenidate-induced locomotor activity in adult female rats by Dib, Tatiana, Martínez-Pinto, Jonathan, Reyes-Parada, Miguel, Torres, Gonzalo E., Sotomayor-Zárate, Ramón

“…•Neonatal TP reduces methylphenidate-induced locomotor activity in female rats.•Neonatal TP reduces accumbal DAT expression in adult female rats.•Neonatal TP…”
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Plasma membrane monoamine transporters: structure, regulation and function by Caron, Marc G, Torres, Gonzalo E, Gainetdinov, Raul R

“…The classical biogenic amine neurotransmitters -- dopamine, noradrenaline, and 5-hydroxytryptamine -- control a variety of functions including locomotion,…”
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Functional connectivity, behavioral and dopaminergic alterations 24 hours following acute exposure to synthetic bath salt drug methylenedioxypyrovalerone by Colon-Perez, Luis M., Pino, Jose A., Saha, Kaustuv, Pompilus, Marjory, Kaplitz, Sherman, Choudhury, Nafisa, Jagnarine, Darin A., Geste, Jean R., Levin, Brandon A., Wilks, Isaac, Setlow, Barry, Bruijnzeel, Adriaan W., Khoshbouei, Habibeh, Torres, Gonzalo E., Febo, Marcelo

“…Among cathinone drugs known as bath salts, methylenedioxypyrovalerone (MDPV) exerts its potent actions via the dopamine (DA) system, and at intoxicating doses…”
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