Search Results - "Torrens, Alexa"

A preclinical model of THC edibles that produces high-dose cannabimimetic responses by English, Anthony, Uittenbogaard, Fleur, Torrens, Alexa, Sarroza, Dennis, Slaven, Anna Veronica Elizabeth, Piomelli, Daniele, Bruchas, Michael R, Stella, Nephi, Land, Benjamin Bruce

“…No preclinical experimental approach enables the study of voluntary oral consumption of high-concentration Δ -tetrahydrocannabinol (THC) and its intoxicating…”
Get full text

Pharmacokinetic, behavioral, and brain activity effects of Δ9-tetrahydrocannabinol in adolescent male and female rats by Ruiz, Christina M., Torrens, Alexa, Castillo, Erik, Perrone, Christina R., Cevallos, Jenny, Inshishian, Victoria C., Harder, Eden V., Justeson, Drew N., Huestis, Marilyn A., Swarup, Vivek, Piomelli, Daniele, Mahler, Stephen V.

“…Δ9-tetrahydrocannabinol (THC) is the intoxicating constituent of cannabis and is responsible for the drug’s reinforcing effects. Retrospective human studies…”
Get full text

Targeting NAAA counters dopamine neuron loss and symptom progression in mouse models of parkinsonism by Palese, Francesca, Pontis, Silvia, Realini, Natalia, Torrens, Alexa, Ahmed, Faizy, Assogna, Francesca, Pellicano, Clelia, Bossù, Paola, Spalletta, Gianfranco, Green, Kim, Piomelli, Daniele

“…The lysosomal cysteine hydrolase N-acylethanolamine acid amidase (NAAA) deactivates palmitoylethanolamide (PEA), a lipid-derived PPAR-α agonist that is…”
Get full text

A preclinical model of THC edibles that produces high-dose cannabimimetic responses by English, Anthony, Uittenbogaard, Fleur, Torrens, Alexa, Sarroza, Dennis, Slaven, Anna Veronica Elizabeth, Piomelli, Daniele, Bruchas, Michael R, Stella, Nephi, Land, Benjamin Bruce

“…No preclinical experimental approach enables the study of voluntary oral consumption of high-concentration Δ 9 -tetrahydrocannabinol (THC) and its intoxicating…”
Get full text

Adolescent exposure to low-dose THC disrupts energy balance and adipose organ homeostasis in adulthood by Lin, Lin, Jung, Kwang-Mook, Lee, Hye-Lim, Le, Johnny, Colleluori, Georgia, Wood, Courtney, Palese, Francesca, Squire, Erica, Ramirez, Jade, Su, Shiqi, Torrens, Alexa, Fotio, Yannick, Tang, Lingyi, Yu, Clinton, Yang, Qin, Huang, Lan, DiPatrizio, Nicholas, Jang, Cholsoon, Cinti, Saverio, Piomelli, Daniele

“…One of cannabis’ most iconic effects is the stimulation of hedonic high-calorie eating—the “munchies”—yet habitual cannabis users are, on average, leaner than…”
Get full text

Nasal Accumulation and Metabolism of Δ9-Tetrahydrocannabinol Following Aerosol (‘Vaping’) Administration in Adolescent Rats by Torrens, Alexa, Ruiz, Christina M., Martinez, Maricela X., Tagne, Alex Mabou, Roy, Pritam, Grimes, Dakota, Ahmed, Faizy, Lallai, Valeria, Inshishian, Victoria, Bautista, Malia, Chen, Yen-Chu, Huestis, Marilyn A., Das, Aditi, Fowler, Christie D., Mahler, Stephen V., Piomelli, Daniele

“…Passive aerosol exposure to Δ 9 -tetrahydrocannabinol (THC) in laboratory animals results in faster onset of action and less extensive liver metabolism…”
Get full text

Comparative Pharmacokinetics of Δ 9 -Tetrahydrocannabinol in Adolescent and Adult Male Mice by Torrens, Alexa, Vozella, Valentina, Huff, Hannah, McNeil, Brandon, Ahmed, Faizy, Ghidini, Andrea, Mahler, Stephen V, Huestis, Marilyn A, Das, Aditi, Piomelli, Daniele

“…We investigated the pharmacokinetic properties of Δ -tetrahydrocannabinol (Δ -THC), the main psychoactive constituent of cannabis, in adolescent and adult male…”
Get full text

Comparative Pharmacokinetics of Δ9-Tetrahydrocannabinol in Adolescent and Adult Male Mice by Torrens, Alexa, Vozella, Valentina, Huff, Hannah, McNeil, Brandon, Ahmed, Faizy, Ghidini, Andrea, Mahler, Stephen V., Huestis, Marilyn A., Das, Aditi, Piomelli, Daniele

“…We investigated the pharmacokinetic properties of Δ 9 -tetrahydrocannabinol (Δ 9 -THC), the main psychoactive constituent of cannabis, in adolescent and adult…”
Get full text

Frequent Low-Dose Δ9-Tetrahydrocannabinol in Adolescence Disrupts Microglia Homeostasis and Disables Responses to Microbial Infection and Social Stress in Young Adulthood by Lee, Hye-Lim, Jung, Kwang-Mook, Fotio, Yannick, Squire, Erica, Palese, Francesca, Lin, Lin, Torrens, Alexa, Ahmed, Faizy, Mabou Tagne, Alex, Ramirez, Jade, Su, Shiqi, Wong, Christina Renee, Jung, Daniel Hojin, Scarfone, Vanessa M., Nguyen, Pauline U., Wood, Marcelo, Green, Kim, Piomelli, Daniele

“…During adolescence, microglia are actively involved in neocortical maturation while concomitantly undergoing profound phenotypic changes. Because the teenage…”
Get full text

A Sensitive Ultrahigh-Performance Liquid Chromatography/Tandem Mass Spectrometry Method for the Simultaneous Analysis of Phytocannabinoids and Endocannabinoids in Plasma and Brain by Ahmed, Faizy, Torrens, Alexa, Mahler, Stephen V, Ferlenghi, Francesca, Huestis, Marilyn A, Piomelli, Daniele

“…Δ -tetrahydrocannabinol (THC) and cannabidiol (CBD) are major chemical constituents of cannabis, which may interact either directly or indirectly with the…”
Get more information

Nasal accumulation and metabolism of Δ9-tetrahydrocannabinol following aerosol (‘vaping’) administration in an adolescent rat model by Torrens, Alexa, Ruiz, Christina M., Martinez, Maricela X., Tagne, Alex Mabou, Roy, Pritam, Grimes, Dakota, Ahmed, Faizy, Lallai, Valeria, Inshishian, Victoria, Bautista, Malia, Chen, Yen-Chu, Huestis, Marilyn A., Das, Aditi, Fowler, Christie D., Mahler, Stephen V., Piomelli, Daniele

“…Passive aerosol exposure to Δ9-tetrahydrocannabinol (THC) in laboratory animals results in faster onset of action and less extensive liver metabolism compared…”
Get full text

Nasal accumulation and metabolism of Δ 9 -tetrahydrocannabinol following aerosol ('vaping') administration in an adolescent rat model by Torrens, Alexa, Ruiz, Christina M, Martinez, Maricela X, Tagne, Alex Mabou, Roy, Pritam, Grimes, Dakota, Ahmed, Faizy, Lallai, Valeria, Inshishian, Victoria, Bautista, Malia, Chen, Yen-Chu, Huestis, Marilyn A, Das, Aditi, Fowler, Christie D, Mahler, Stephen V, Piomelli, Daniele

“…Passive aerosol exposure to Δ -tetrahydrocannabinol (THC) in laboratory animals results in faster onset of action and less extensive liver metabolism compared…”
Get full text

Comparative Pharmacokinetics of Δ 9 -Tetrahydrocannabinol in Adolescent and Adult Male and Female Rats by Torrens, Alexa, Roy, Pritam, Lin, Lin, Vu, Cindy, Grimes, Dakota, Inshishian, Victoria C, Montesinos, Johanna S, Ahmed, Faizy, Mahler, Stephen V, Huestis, Marylin A, Das, Aditi, Piomelli, Daniele

“…Studies in rodent models have shown that adolescent exposure to Δ -THC, the psychotropic constituent of cannabis, produces long-lasting alterations in brain…”
Get more information

Frequent Low-Dose Δ 9 -Tetrahydrocannabinol in Adolescence Disrupts Microglia Homeostasis and Disables Responses to Microbial Infection and Social Stress in Young Adulthood by Lee, Hye-Lim, Jung, Kwang-Mook, Fotio, Yannick, Squire, Erica, Palese, Francesca, Lin, Lin, Torrens, Alexa, Ahmed, Faizy, Mabou Tagne, Alex, Ramirez, Jade, Su, Shiqi, Wong, Christina Renee, Jung, Daniel Hojin, Scarfone, Vanessa M, Nguyen, Pauline U, Wood, Marcelo, Green, Kim, Piomelli, Daniele

“…During adolescence, microglia are actively involved in neocortical maturation while concomitantly undergoing profound phenotypic changes. Because the teenage…”
Get full text

Pharmacokinetic, behavioral, and brain activity effects of Δ 9 -tetrahydrocannabinol in adolescent male and female rats by Ruiz, Christina M, Torrens, Alexa, Castillo, Erik, Perrone, Christina R, Cevallos, Jenny, Inshishian, Victoria C, Harder, Eden V, Justeson, Drew N, Huestis, Marilyn A, Swarup, Vivek, Piomelli, Daniele, Mahler, Stephen V

“…Δ -tetrahydrocannabinol (THC) is the intoxicating constituent of cannabis and is responsible for the drug's reinforcing effects. Retrospective human studies…”
Get full text