Search Results - "Torre, Eugenio"
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Reciprocal Activation of Prostate Cancer Cells and Cancer-Associated Fibroblasts Stimulates Epithelial-Mesenchymal Transition and Cancer Stemness
Published in Cancer research (Chicago, Ill.) (01-09-2010)“…Although cancer-associated fibroblasts (CAF) are key determinants in the malignant progression of cancer, their functional contribution to this process is…”
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Contribution of acidic melanoma cells undergoing epithelial-to-mesenchymal transition to aggressiveness of non-acidic melanoma cells
Published in Clinical & experimental metastasis (01-04-2014)“…Tumor cell plasticity largely depends on epithelial-to-mesenchymal transition (EMT) and its reversion. It was ascertained that EMT characterizes disease…”
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3
ETV4 promotes late development of prostatic intraepithelial neoplasia and cell proliferation through direct and p53-mediated downregulation of p21
Published in Journal of hematology and oncology (13-08-2020)“…ETV4 is one of the ETS proteins overexpressed in prostate cancer (PC) as a result of recurrent chromosomal translocations. In human prostate cell lines, ETV4…”
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Therapy-Induced Stromal Senescence Promoting Aggressiveness of Prostate and Ovarian Cancer
Published in Cells (Basel, Switzerland) (01-12-2022)“…Cancer progression is supported by the cross-talk between tumor cells and the surrounding stroma. In this context, senescent cells in the tumor…”
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Coenzyme Q10 instilled as eye drops on the cornea reaches the retina and protects retinal layers from apoptosis in a mouse model of kainate-induced retinal damage
Published in Investigative ophthalmology & visual science (17-12-2012)“…To evaluate if coenzyme Q10 (CoQ10) can protect retinal ganglion cells (RGCs) from apoptosis and, when instilled as eye drops on the cornea, if it can reach…”
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GDF5 regulates TGFß-dependent angiogenesis in breast carcinoma MCF-7 cells: in vitro and in vivo control by anti-TGFß peptides
Published in PloS one (30-11-2012)“…TGFß overproduction in cancer cells is one of the main characteristics of late tumor progression being implicated in metastasis, tumor growth, angiogenesis and…”
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Hypoxia-resistant profile implies vulnerability of cancer stem cells to physiological agents, which suggests new therapeutic targets
Published in Cell cycle (Georgetown, Tex.) (15-01-2014)“…We have previously shown that peculiar metabolic features of cell adaptation and survival in hypoxia imply growth restriction points that are typical of…”
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A pathobiologic pathway linking thrombopoietin, GATA-1, and TGF-β1 in the development of myelofibrosis
Published in Blood (01-05-2005)“…Idiopathic myelofibrosis (IM) is a disease characterized by marrow fibrosis, abnormal stem/progenitor cell trafficking, and extramedullary hematopoiesis…”
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Coenzyme Q10 protects retinal cells from apoptosis induced by radiation in vitro and in vivo
Published in Journal of radiation research (01-09-2012)“…The key pathogenetic event of many retinopathies is apoptosis of retinal cells. Our previous studies have demonstrated that Coenzyme Q10 (CoQ10) prevents…”
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Systemic Sclerosis-Endothelial Cell Antiangiogenic Pentraxin 3 and Matrix Metalloprotease 12 Control Human Breast Cancer Tumor Vascularization and Development in Mice
Published in Neoplasia (New York, N.Y.) (01-10-2009)“…We have previously shown that endothelial cell matrix metalloprotease 12 (MMP12) and pentraxin 3 (PTX3) overproduction is the main alteration accounting for…”
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An observational study of Venlafaxine and CYP2D6 in clinical practice
Published in Clinical laboratory (Heidelberg) (2014)“…Venlafaxine (V) is a serotonin-norepinephrine selective reuptake inhibitor, mainly metabolized by cytochrome P4502D6 (CYP2D6). CYP2D6 polymorphisms result in a…”
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Assessment of Inorganic Phosphate Intake by the Measurement of the Phosphate/Urea Nitrogen Ratio in Urine
Published in Nutrients (20-01-2021)“…In chronic kidney disease (CKD) patients, it would be desirable to reduce the intake of inorganic phosphate (P) rather than limit the intake of P contained in…”
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HIF-1α stabilization by mitochondrial ROS promotes Met-dependent invasive growth and vasculogenic mimicry in melanoma cells
Published in Free radical biology & medicine (15-08-2011)“…The “angiogenic switch” during tumor progression is increasingly recognized as a milestone event in tumorigenesis, although the surprising prometastatic effect…”
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Carbonic anhydrase IX from cancer-associated fibroblasts drives epithelial-mesenchymal transition in prostate carcinoma cells
Published in Cell cycle (Georgetown, Tex.) (01-06-2013)“…Extracellular acidification, a mandatory feature of several malignancies, has been mainly correlated with metabolic reprogramming of tumor cells toward Warburg…”
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uPA/uPAR system activation drives a glycolytic phenotype in melanoma cells
Published in International journal of cancer (15-09-2017)“…In this manuscript, we show the involvement of the uPA/uPAR system in the regulation of aerobic glycolysis of melanoma cells. uPAR over‐expression in human…”
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Cinema in the training of psychiatry residents: focus on helping relationships
Published in BMC medical education (21-06-2013)“…Medical schools are currently charged with a lack of education as far as empathic/relational skills and the meaning of being a health-care provider are…”
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HDAC1 controls CIP2A transcription in human colorectal cancer cells
Published in Oncotarget (03-05-2016)“…This work describes the effectiveness of HDAC-inhibitor (S)-2 towards colorectal cancer (CRC) HCT116 cells in vitro by inducing cell cycle arrest and…”
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Endothelial sphingosine kinase/SPNS2 axis is critical for vessel-like formation by human mesoangioblasts
Published in Journal of molecular medicine (Berlin, Germany) (01-10-2015)“…The interaction between endothelial cells and pericytes is crucial for the stabilization of newly formed vessels in angiogenesis. The comprehension of the…”
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uPA/uPAR system activation drives a glycolytic phenotype in melanoma cells: uPAR and melanoma cell metabolism
Published in International journal of cancer (15-09-2017)Get full text
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Suicide attempts and emergency room psychiatric consultation
Published in BMC psychiatry (05-02-2015)“…Suicidal behaviours are major public health concerns worldwide. They are associated with risk factors that vary with age and gender, occur in combination, and…”
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