Search Results - "Torre, Beatriz"

The Pharmaceutical Industry in 2018. An Analysis of FDA Drug Approvals from the Perspective of Molecules by G de la Torre, Beatriz, Albericio, Fernando

“…The Food and Drug Administration approved 59 new drugs (42 New Chemical Entities and 17 Biologics) during 2018. This number breaks the previous record of 53…”
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The Pharmaceutical Industry in 2019. An Analysis of FDA Drug Approvals from the Perspective of Molecules by de la Torre, Beatriz G, Albericio, Fernando

“…During 2019, the US Food and Drug Administration (FDA) approved 48 new drugs (38 New Chemical Entities and 10 Biologics). Although this figure is slightly…”
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Liquid-Phase Peptide Synthesis (LPPS): A Third Wave for the Preparation of Peptides by Sharma, Anamika, Kumar, Ashish, de la Torre, Beatriz G., Albericio, Fernando

“…Since the last century, peptides have gained wide acceptance as drugs, with almost 100 already in the market and a large number in the pipeline. In this…”
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The Pharmaceutical Industry in 2021. An Analysis of FDA Drug Approvals from the Perspective of Molecules by de la Torre, Beatriz G, Albericio, Fernando

“…Similar to last year, 2021 will be remembered for the COVID-19 pandemic. Although five vaccines have been approved by the two most important drug regulatory…”
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The Pharmaceutical Industry in 2020. An Analysis of FDA Drug Approvals from the Perspective of Molecules by Torre, Beatriz G de la, Albericio, Fernando

“…Although the pharmaceutical industry will remember 2020 as the year of COVID-19, it is important to highlight that this year has been the second-best-together…”
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Peptide Therapeutics 2.0 by de la Torre, Beatriz G, Albericio, Fernando

“…In recent years, the peptide drug discovery field has shown a high level of dynamism, with hundreds of academic groups working on this topic, the creation of…”
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The Pharmaceutical Industry in 2022: An Analysis of FDA Drug Approvals from the Perspective of Molecules by de la Torre, Beatriz G, Albericio, Fernando

“…While 2021 ended with the world engulfed in the COVID-19 Omicron wave, 2022 has ended in almost all countries, except China, with COVID-19 being likened to the…”
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Breaking a Couple: Disulfide Reducing Agents by Mthembu, Sinenhlanhla N., Sharma, Anamika, Albericio, Fernando, Torre, Beatriz G.

“…Cysteine is present in a large number of natural and synthetic (bio)molecules. Although the thiol side chain of Cys can be in a free form, in most cases it…”
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Linkers: An Assurance for Controlled Delivery of Antibody-Drug Conjugate by Sheyi, Rotimi, de la Torre, Beatriz G, Albericio, Fernando

“…As one of the major therapeutic options for cancer treatment, chemotherapy has limited selectivity against cancer cells. Consequently, this therapeutic…”
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N,N‐Dimethyl Formamide European Restriction Demands Solvent Substitution in Research and Development by Sherwood, James, Albericio, Fernando, Torre, Beatriz G.

“…As of December 2023, the use of common solvent N,N‐dimethyl formamide (DMF) will be restricted in the European Union because of its reproductive health hazard…”
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The Pharmaceutical Industry in 2023: An Analysis of FDA Drug Approvals from the Perspective of Molecules by de la Torre, Beatriz G, Albericio, Fernando

“…With the COVID-19 pandemic behind us, the U.S. Food and Drug Administration (FDA) has approved 55 new drugs in 2023, a figure consistent with the number…”
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The Pharmaceutical Industry in 2017. An Analysis of FDA Drug Approvals from the Perspective of Molecules by de la Torre, Beatriz G, Albericio, Fernando

“…This is an analysis from a chemical point of view of the 46 drugs (34 New Chemical Entities and 12 Biologics) approved by the FDA during 2017. The drugs…”
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N‐Butylpyrrolidinone for Solid‐Phase Peptide Synthesis is Environmentally Friendlier and Synthetically Better than DMF by Kumar, Ashish, Alhassan, Mahama, Lopez, John, Albericio, Fernando, Torre, Beatriz G.

“…Solid‐phase peptide synthesis (SPPS) is the method of choice for the preparation of peptides in both laboratory scale and large production. Although the…”
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The challenge of peptide nucleic acid synthesis by Nandhini, K P, Shaer, Danah Al, Albericio, Fernando, de la Torre, Beatriz G

“…Peptide nucleic acids (PNAs) are an important class of DNA/RNA mimics that can hybridize complementary chains of nucleic acids with high affinity and…”
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Short AntiMicrobial Peptides (SAMPs) as a class of extraordinary promising therapeutic agents by Ramesh, Suhas, Govender, Thavendran, Kruger, Hendrik G., de la Torre, Beatriz G., Albericio, Fernando

“…The emergence of multidrug resistant bacteria has a direct impact on global public health because of the reduced potency of existing antibiotics against…”
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2020 FDA TIDES (Peptides and Oligonucleotides) Harvest by Al Musaimi, Othman, Al Shaer, Danah, Albericio, Fernando, de la Torre, Beatriz G

“…2020 has been an extremely difficult and challenging year as a result of the coronavirus disease 2019 (COVID-19) pandemic and one in which most efforts have…”
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The Pharmaceutical Industry in 2016. An Analysis of FDA Drug Approvals from a Perspective of the Molecule Type by Torre, Beatriz G de la, Albericio, Fernando

“…This is an analysis from a chemical point of view of the 22 drugs accepted by the FDA during 2016. The different drugs from the 2016 "harvest" have been…”
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Disulfide-Based Protecting Groups for the Cysteine Side Chain by Chakraborty, Amit, Sharma, Anamika, Albericio, Fernando, de la Torre, Beatriz G

“…Two new disulfide-based protecting groups (SIT and MOT) are proposed for Cys thiol in the substitution of StBu, which is often difficult to remove. Both groups…”
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Chemoselective Disulfide Formation by Thiol-Disulfide Interchange in SIT-Protected Cysteinyl Peptides by Chakraborty, Amit, Albericio, Fernando, de la Torre, Beatriz G

“…Chemoselective disulfide formation is accomplished through a thiol-disulfide interchange approach using sec-isoamyl mercaptan (SIT) as an alkyl…”
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2021 FDA TIDES (Peptides and Oligonucleotides) Harvest by Al Shaer, Danah, Al Musaimi, Othman, Albericio, Fernando, de la Torre, Beatriz G

“…From the medical, pharmaceutical, and social perspectives, 2021 has been a year dominated by the COVID-19 pandemic. However, despite this global health crisis,…”
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