Search Results - "Torrance, DS"

TNF Receptor-Deficient Mice Reveal Divergent Roles for p55 and p75 in Several Models of Inflammation by Peschon, Jacques J, Torrance, Dauphine S, Stocking, Kim L, Glaccum, Moira B, Otten, Carol, Willis, Cynthia R, Charrier, Keith, Morrissey, Philip J, Ware, Carol B, Mohler, Kendall M

“…The pleiotropic activities of the potent proinflammatory cytokine TNF are mediated by two structurally related, but functionally distinct, receptors, p55 and…”
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Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA expression correlates with recovery by Kennedy, MK, Torrance, DS, Picha, KS, Mohler, KM

“…Experimental autoimmune encephalomyelitis (EAE) serves as an important animal model for understanding the events that lead to immune-mediated inflammation and…”
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Soluble tumor necrosis factor (TNF) receptors are effective therapeutic agents in lethal endotoxemia and function simultaneously as both TNF carriers and TNF antagonists by Mohler, KM, Torrance, DS, Smith, CA, Goodwin, RG, Stremler, KE, Fung, VP, Madani, H, Widmer, MB

“…Two forms (monomeric or dimeric) of the extracellular, ligand-binding portion of the human p80 cell-surface receptor for TNF were used to antagonize TNF…”
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Protection against a lethal dose of endotoxin by an inhibitor of tumour necrosis factor processing by Mohler, Kendall M, Sleath, Paul R, Fitzner, Jeffrey N, Cerretti, Douglas Pat, Alderson, Mark, Kerwar, Suresh S, Torranee, Dauphine S, Otten-Evans, Carol, Greenstreet, Teresa, Weerawarna, Kumudini, Kronheim, Shirley R, Petersen, Melissa, Gerhart, Mary, Kozlosky, Carl J, March, Carl J, Black, Roy A

“…Tumour necrosis factor (tumour necrosis factor-alpha/cachectin) plays a critical role in certain physiological defensive responses but causes severe damage to…”
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