Search Results - "Torrado‐Santiago, Santiago"

Amphotericin B formulations and drug targeting by Torrado, J J, Espada, R, Ballesteros, M P, Torrado-Santiago, S

“…Amphotericin B is a low-soluble polyene antibiotic which is able to self-aggregate. The aggregation state can modify its activity and pharmacokinetical…”
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Development of a Solid Dispersion of Nystatin with Maltodextrin as a Carrier Agent: Improvements in Antifungal Efficacy against Candida spp. Biofilm Infections by Benavent, Carlos, Torrado-Salmerón, Carlos, Torrado-Santiago, Santiago

“…The aim of this study was to improve the treatment of biofilms through the use of nystatin solid dispersions developed using maltodextrins as a hyperosmotic…”
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Submicellar liquid chromatography with fluorescence detection improves the analysis of naproxen in plasma and brain tissue by García‐Herrero, Víctor, Torrado‐Salmerón, Carlos, García‐Rodríguez, Juan José, Torrado, Guillermo, Torrado‐Santiago, Santiago

“…Rapid, simple, and sensitive submicellar liquid chromatography with fluorescence detection was developed and validated to quantify naproxen in plasma and brain…”
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Development of novel benznidazole formulations: Physicochemical characterization and in vivo evaluation on parasitemia reduction in Chagas disease by Palmeiro-Roldán, Ricardo, Fonseca-Berzal, Cristina, Gómez-Barrio, Alicia, Arán, Vicente J., Escario, José A., Torrado-Durán, Susana, Torrado-Santiago, Santiago

“…[Display omitted] This work aims to develop novel benznidazole (BZN) solid dispersions (SD) to improve its solubility and bioavailability properties…”
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Improvement in the Oral Bioavailability and Efficacy of New Ezetimibe Formulations—Comparative Study of a Solid Dispersion and Different Micellar Systems by Torrado-Salmerón, Carlos, Guarnizo-Herrero, Víctor, Gallego-Arranz, Teresa, del Val-Sabugo, Yvonne, Torrado, Guillermo, Morales, Javier, Torrado-Santiago, Santiago

“…Ezetimibe (EZ) is a poorly water-soluble drug with low bioavailability. Strategies such as solid dispersions (SD) and micellar systems (MS) were developed to…”
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Topical Meloxicam Hydroxypropyl Guar Hydrogels Based on Low-Substituted Hydroxypropyl Cellulose Solid Dispersions by Dahma, Zaid, Torrado-Salmerón, Carlos, Álvarez-Álvarez, Covadonga, Guarnizo-Herrero, Víctor, Martínez-Alonso, Borja, Torrado, Guillermo, Torrado-Santiago, Santiago, de la Torre-Iglesias, Paloma Marina

“…Meloxicam (MX) is a poorly water-soluble drug with severe gastrointestinal side effects. Topical hydrogel of hydroxypropyl guar (HPG) was formulated using a…”
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Multiparticulate Systems of Ezetimibe Micellar System and Atorvastatin Solid Dispersion Efficacy of Low-Dose Ezetimibe/Atorvastatin on High-Fat Diet-Induced Hyperlipidemia and Hepatic Steatosis in Diabetic Rats by Torrado-Salmerón, Carlos, Guarnizo-Herrero, Víctor, Henriques, Joana, Seiça, Raquel, Sena, Cristina M, Torrado-Santiago, Santiago

“…The aim of this study was to develop multiparticulate systems with a combination of ezetimibe micellar systems and atorvastatin solid dispersions using…”
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Improvement of the surface hydrophilic properties of naproxen particles with addition of hydroxypropylmethyl cellulose and sodium dodecyl sulphate: In vitro and in vivo studies by García-Herrero, Víctor, Torrado, Carlos, García-Rodríguez, Juan José, López-Sánchez, Alicia, Torrado, Susana, Torrado-Santiago, Santiago

“…[Display omitted] In this study, a new surface-modified naproxen was developed to enhance brain concentration in acute migraine treatment. Fast-dissolving…”
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The influence of CYP2C19 genetic polymorphism on the pharmacokinetics/- pharmacodynamics of proton pump inhibitor-containing Helicobacter pylori treatments by Serrano, Dolores, Torrado, Susana, Torrado-Santiago, Santiago, Gisbert, Javier P

“…Proton pump inhibitors (PPIs) are the most potent acid suppressants available. PPIs undergo hepatic metabolism via the CYP2C system for the isoforms CYP2C19…”
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Enhanced bioavailability and anthelmintic efficacy of mebendazole in redispersible microparticles with low-substituted hydroxypropylcellulose by de la Torre-Iglesias, Paloma Marina, García-Rodriguez, Juan José, Torrado, Guillermo, Torrado, Susana, Torrado-Santiago, Santiago, Bolás-Fernández, Francisco

“…Mebendazole (MBZ) is an extremely insoluble and therefore poorly absorbed drug and the variable clinical results may correlate with blood concentrations. The…”
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Chitosan–carboxymethylcellulose interpolymer complexes for gastric-specific delivery of clarithromycin by Gómez-Burgaz, M., García-Ochoa, B., Torrado-Santiago, S.

“…Chitosan (CS) and carboxymethylcellulose (CMC) sodium interpolymer complexes were formed using the novel method “tablets-in-capsule” for stomach drug delivery…”
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A multivariate investigation into the relationship between pharmaceutical characteristics and patient preferences of bioequivalent ibuprofen tablets by Alonso, Tatiana R, Gagol, Adrianna, Scherer, Maximilian, Matji, Antonio, Torrado-Santiago, Santiago, Serrano, Dolores R, Garcia-Arieta, Alfredo, Torrado, Juan J

“…In Spain the price of all ibuprofen 600 mg tablet generic products is the same due to reimbursement existing rules so for the patient there is not any economic…”
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Treatment of Experimental Visceral Leishmaniasis with Amphotericin B in Stable Albumin Microspheres by SANCHEZ-BRUNETE, J. A, DEA, M. A, RAMA, S, BOLAS, F, ALUNDA, J. M, RAPOSO, R, MENDEZ, M. T, TORRADO-SANTIAGO, S, TORRADO, J. J

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Spray-Dried Powders as Nasal Absorption Enhancers of Cyanocobalamin by GARCÍA-ARIETA, Alfredo, TORRADO-SANTIAGO, Santiago, GOYA, Luis, TORRADO, Juan José

“…The aim of this work is to describe and characterize a new spray-drying procedure for the production of nasal powders as an alternative to the conventional…”
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Characterization of Physical State of Mannitol after Freeze-Drying: Effect of Acetylsalicylic Acid as a Second Crystalline Cosolute by Torrado, Susana, Torrado, Santiago

“…Freeze-drying of mixed solutes is a preparative technique widely used in the pharmaceutical industry. The presence of an amorphous form or changes in the…”
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Poly (acrylic acid) chitosan interpolymer complexes for stomach controlled antibiotic delivery by de la Torre, Paloma M., Torrado, Guillermo, Torrado, Santiago

“…The aim of this study was to develop a stomach‐specific drug delivery system to increase the efficacy of amoxicillin against Helicobacter pylori. Polyacrylic…”
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Microcapsules formulated in the enteric coating copolymer Eudragit L100 as delivery systems for oral vaccination against infections by gastrointestinal nematode parasites by Dea-Ayuela, Maria A., Rama-Iñiguez, Sara, Torrado-Santiago, S., Bolas-Fernandez, F.

“…Microcapsules using the copolymer of methacrylic acid (Eudragit L100) were formulated for oral delivery of vaccines against the enteral/parenteral nematode…”
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Improvement of the pharmacokinetic/pharmacodynamic relationship in the treatment of invasive aspergillosis with voriconazole. Reduced drug toxicity through novel rapid release formulations by Gallego-Arranz, Teresa, Pérez-Cantero, Alba, Torrado-Salmerón, Carlos, Guarnizo-Herrero, Víctor, Capilla, Javier, Torrado-Durán, Santiago

“…[Display omitted] •Micellar systems diminished crystallinity of voriconazole and increased its dissolution rate.•Minimum inhibitory concentration was lower…”
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Preparation, dissolution and characterization of albendazole solid dispersions by Torrado, Susana, Torrado, Santiago, Torrado, Juan José, Cadórniga, Rafael

“…In this study, solid dispersion systems of the sparingly water soluble drug, albendazole (ABZ), were mixed with varying concentrations of polyvinylpyrrolidone…”
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Influence of the vehicle on the properties and efficacy of microparticles containing amphotericin B by Sánchez-Brunete, J. A., Dea, M. A., Rama, S., Bolás, F., Alunda, J. M., Torrado-Santiago, S., Torrado, J. J.

“…New microparticles containing amphotericin B (AMB) have been developed and manufactured by spray drying. To this end albumin, polylactic-co-glycolic acids…”
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