Search Results - "Torok, M Estee"

Rapid implementation of SARS-CoV-2 sequencing to investigate cases of health-care associated COVID-19: a prospective genomic surveillance study by Meredith, Luke W, Hamilton, William L, Warne, Ben, Houldcroft, Charlotte J, Hosmillo, Myra, Jahun, Aminu S, Curran, Martin D, Parmar, Surendra, Caller, Laura G, Caddy, Sarah L, Khokhar, Fahad A, Yakovleva, Anna, Hall, Grant, Feltwell, Theresa, Forrest, Sally, Sridhar, Sushmita, Weekes, Michael P, Baker, Stephen, Brown, Nicholas, Moore, Elinor, Popay, Ashley, Roddick, Iain, Reacher, Mark, Gouliouris, Theodore, Peacock, Sharon J, Dougan, Gordon, Török, M Estée, Goodfellow, Ian

“…The burden and influence of health-care associated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections is unknown. We aimed to examine the…”
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Patterns of within-host genetic diversity in SARS-CoV-2 by Tonkin-Hill, Gerry, Martincorena, Inigo, Amato, Roberto, Lawson, Andrew R J, Gerstung, Moritz, Johnston, Ian, Jackson, David K, Park, Naomi, Lensing, Stefanie V, Quail, Michael A, Gonçalves, Sónia, Ariani, Cristina, Spencer Chapman, Michael, Hamilton, William L, Meredith, Luke W, Hall, Grant, Jahun, Aminu S, Chaudhry, Yasmin, Hosmillo, Myra, Pinckert, Malte L, Georgana, Iliana, Yakovleva, Anna, Caller, Laura G, Caddy, Sarah L, Feltwell, Theresa, Khokhar, Fahad A, Houldcroft, Charlotte J, Curran, Martin D, Parmar, Surendra, Alderton, Alex, Nelson, Rachel, Harrison, Ewan M, Sillitoe, John, Bentley, Stephen D, Barrett, Jeffrey C, Torok, M Estee, Goodfellow, Ian G, Langford, Cordelia, Kwiatkowski, Dominic

“…Monitoring the spread of SARS-CoV-2 and reconstructing transmission chains has become a major public health focus for many governments around the world. The…”
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Systematic Surveillance Detects Multiple Silent Introductions and Household Transmission of Methicillin-Resistant Staphylococcus aureus USA300 in the East of England by Toleman, Michelle S., Reuter, Sandra, Coll, Francesc, Harrison, Ewan M., Blane, Beth, Brown, Nicholas M., Török, M. Estée, Parkhill, Julian, Peacock, Sharon J.

“…Background. The spread of USA300 methicillin-resistant Staphylococcus aureus (MRSA) across the United States resulted in an epidemic of infections. In Europe,…”
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Building a genomic framework for prospective MRSA surveillance in the United Kingdom and the Republic of Ireland by Reuter, Sandra, Török, M Estée, Holden, Matthew T G, Reynolds, Rosy, Raven, Kathy E, Blane, Beth, Donker, Tjibbe, Bentley, Stephen D, Aanensen, David M, Grundmann, Hajo, Feil, Edward J, Spratt, Brian G, Parkhill, Julian, Peacock, Sharon J

“…The correct interpretation of microbial sequencing data applied to surveillance and outbreak investigation depends on accessible genomic databases to provide…”
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Duration of exposure to multiple antibiotics is associated with increased risk of VRE bacteraemia: a nested case-control study by Gouliouris, Theodore, Warne, Ben, Cartwright, Edward J P, Bedford, Luke, Weerasuriya, Chathika K, Raven, Kathy E, Brown, Nick M, Török, M Estée, Limmathurotsakul, Direk, Peacock, Sharon J

“…Abstract Background VRE bacteraemia has a high mortality and continues to defy control. Antibiotic risk factors for VRE bacteraemia have not been adequately…”
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Superspreaders drive the largest outbreaks of hospital onset COVID-19 infections by Illingworth, Christopher Jr, Hamilton, William L, Warne, Ben, Routledge, Matthew, Popay, Ashley, Jackson, Chris, Fieldman, Tom, Meredith, Luke W, Houldcroft, Charlotte J, Hosmillo, Myra, Jahun, Aminu S, Caller, Laura G, Caddy, Sarah L, Yakovleva, Anna, Hall, Grant, Khokhar, Fahad A, Feltwell, Theresa, Pinckert, Malte L, Georgana, Iliana, Chaudhry, Yasmin, Curran, Martin D, Parmar, Surendra, Sparkes, Dominic, Rivett, Lucy, Jones, Nick K, Sridhar, Sushmita, Forrest, Sally, Dymond, Tom, Grainger, Kayleigh, Workman, Chris, Ferris, Mark, Gkrania-Klotsas, Effrossyni, Brown, Nicholas M, Weekes, Michael P, Baker, Stephen, Peacock, Sharon J, Goodfellow, Ian G, Gouliouris, Theodore, de Angelis, Daniela, Török, M Estée

“…SARS-CoV-2 is notable both for its rapid spread, and for the heterogeneity of its patterns of transmission, with multiple published incidences of…”
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Genomic epidemiology of COVID-19 in care homes in the east of England by Hamilton, William L, Tonkin-Hill, Gerry, Smith, Emily R, Aggarwal, Dinesh, Houldcroft, Charlotte J, Warne, Ben, Meredith, Luke W, Hosmillo, Myra, Jahun, Aminu S, Curran, Martin D, Parmar, Surendra, Caller, Laura G, Caddy, Sarah L, Khokhar, Fahad A, Yakovleva, Anna, Hall, Grant, Feltwell, Theresa, Pinckert, Malte L, Georgana, Iliana, Chaudhry, Yasmin, Brown, Colin S, Gonçalves, Sonia, Amato, Roberto, Harrison, Ewan M, Brown, Nicholas M, Beale, Mathew A, Spencer Chapman, Michael, Jackson, David K, Johnston, Ian, Alderton, Alex, Sillitoe, John, Langford, Cordelia, Dougan, Gordon, Peacock, Sharon J, Kwiatowski, Dominic P, Goodfellow, Ian G, Torok, M Estee

“…COVID-19 poses a major challenge to care homes, as SARS-CoV-2 is readily transmitted and causes disproportionately severe disease in older people. Here, 1167…”
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Dynamic Prediction of Death in Patients With Tuberculous Meningitis Using Time-updated Glasgow Coma Scale and Plasma Sodium Measurements by Thao, Le Thi Phuong, Wolbers, Marcel, Heemskerk, A Dorothee, Thi Hoang Mai, Nguyen, Thi Minh Ha, Dang, Thi Hong Chau, Tran, Hoan Phu, Nguyen, Van Vinh Chau, Nguyen, Caws, Maxine, Huu Lan, Nguyen, Dang Anh Thu, Do, Thuy Thuong Thuong, Nguyen, Day, Jeremy, Torok, M Estee, Duc Bang, Nguyen, Thwaites, Guy E, Geskus, Ronald B

“…Abstract Background Pretreatment predictors of death from tuberculous meningitis (TBM) are well established, but whether outcome can be predicted more…”
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Applying prospective genomic surveillance to support investigation of hospital-onset COVID-19 by Hamilton, William L, Fieldman, Tom, Jahun, Aminu, Warne, Ben, Illingworth, Christopher J R, Jackson, Chris, Blane, Beth, Moore, Elinor, Weekes, Michael P, Peacock, Sharon J, De Angelis, Daniela, Goodfellow, Ian, Gouliouris, Theodore, Török, M Estée, Curran, Martin D, Parmar, Surendra, Hosmillo, Myra, Chaudhry, Yasmin, Pinckert, Malte L, Georgana, Iliana, Izuagbe, Rhys, Ferris, Mark, Workman, Chris, Jones, Nick K, Rivett, Lucy, Sparkes, Dominic, Routledge, Matthew, Enoch, David, Whitehorn, James, Moody, Christine, Brennan, Liam, Smith, Richard, Tsui, Rachel, Bousfield, Rachel, Pocock, Joanna, Toleman, Michelle, Payne, Helen, Coscione, Suny, Myers, Chloe, Sharrocks, Katherine, Ravji, Pooja, Leong, Clare, Ramsay, Isobel

“…[...]changes in SARS-CoV-2 diagnostic methods resulted in technical difficulties in obtaining sufficient good-quality genetic material for sequencing. [...]the…”
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First Report of Salmonella enterica Serotype Paratyphi A Azithromycin Resistance Leading to Treatment Failure by Molloy, Aoife, Nair, Satheesh, Cooke, Fiona J, Wain, John, Farrington, Mark, Lehner, Paul J, Torok, M. Estee

“…The prevalence of Salmonella enterica serotype Paratyphi A infection is increasing, and multidrug resistance is a well-recognized problem. Resistance to…”
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Challenges and opportunities for conducting a vaccine trial during the COVID-19 pandemic in the United Kingdom by Török, M Estée, Underwood, Benjamin R, Toshner, Mark, Waddington, Claire, Sidhom, Emad, Sharrocks, Katherine, Bousfield, Rachel, Summers, Charlotte, Saunders, Caroline, McIntyre, Zoe, Morris, Helen, Piper, Jo, Calderon, Gloria, Dennis, Sarah, Assari, Tracy, de Rotrou, Anita Marguerie, Shaw, Ashley, Bradley, John, O’Brien, John, Rintoul, Robert C, Smith, Ian, Bullmore, Ed, Chatterjee, Krishna, Ribeiro, Carla, Pickup, Lorinda, de Jesus, Ranalie, Brookes, Karen, Vargas, Phoebe, McMahon, Caroline, Macor, Chiara, Pasquale, Ciro, Bermperi, Areti, Kourampa, Evgenia, Fabiculcana, Marivic, Zerudo, Julie Ann, Mendoza, Vivien, Fuller, Stewart, Glemas, Claire, Baker, Sharon, Lyons, Greta, Bishop, Marina, Coleman, Siobhan, Thomas, Naomi, Mlilo, Vince, Stanton, Edward, Michel, Rachel, Philips, Julie, Rice, Heidi, Garner, Lucie, Rosa, Francesca, Victor, Saji, Zamikula, Julie, Mepham, Sue, Hajee, Fatima, Quijano-Campos, Juan Carlos, Watson, Laura, Georgiou, Christopher, Worsley, Jieniean, Shamtally-Amode, Djamilla, Rahimi, Ferishta, Jones, Heather, Cruz, Isabel, Lindsay, Gayle, Sparke, Christian, Chapman, Anna, Keating-Fedders, Katie, Fahey, Codie, Johnson, Danielle, Worboys, Lucy, Hargreaves, Simone, Bucke, Ashlea, Carr, Lindsay, Hampshire, Jackie, Richardson, Tracy, Sharpe, Jenny, Whitehead, Lynne, Vyse, Naval, Kelleher, Stephen, Sherwood, Mary-Beth, Hughes, Vicki, Giraud, Kim

“…The COVID-19 pandemic has resulted in unprecedented challenges for healthcare systems worldwide. It has also stimulated research in a wide range of areas…”
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Dexamethasone in Vietnamese Adolescents and Adults with Bacterial Meningitis by Mai, Nguyen Thi Hoang, Chau, Tran Thi Hong, Chau, Nguyen van Vinh, Thwaites, Guy, Chuong, Ly Van, Sinh, Dinh Xuan, Nghia, Ho Dang Trung, Tuan, Phung Quoc, Phong, Nguyen Duy, Phu, Nguyen Hoan, Diep, To Song, Duong, Nguyen Minh, Campbell, James, Schultsz, Constance, Parry, Chris, Torok, M. Estee, White, Nicholas, Chinh, Nguyen Tran, Hien, Tran Tinh, Stepniewska, Kasia, Farrar, Jeremy J

“…In this randomized, placebo-controlled trial involving 435 adolescents and adults with meningitis in Vietnam, the use of adjunctive dexamethasone did not…”
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The clinical, genomic, and microbiological profile of invasive multi-drug resistant Escherichia coli in a major teaching hospital in the United Kingdom by Hamilton, William L, Coscione, Suny, Maes, Mailis, Warne, Ben, Pike, Lindsay J, Khokhar, Fahad A, Blane, Beth, Brown, Nicholas M, Gouliouris, Theodore, Dougan, Gordon, Török, M Estée, Baker, Stephen

“…is a ubiquitous component of the human gut microbiome, but is also a common pathogen, causing around 40, 000 bloodstream infections (BSI) in the United Kingdom…”
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Comparison of two chromogenic media for the detection of vancomycin-resistant enterococcal carriage by nursing home residents by Gouliouris, Theodore, Blane, Beth, Brodrick, Hayley J, Raven, Kathy E, Ambridge, Kirsty E, Kidney, Angela D, Hadjirin, Nazreen F, Török, M. Estée, Limmathurotsakul, Direk, Peacock, Sharon J

“…Abstract We compared ChromID VRE and Brilliance VRE media for the detection of vancomycin-resistant enterococci (VRE). Using a panel of 28 enterococcal…”
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Clinical and microbiological features of HIV-associated tuberculous meningitis in Vietnamese adults by Torok, M Estee, Chau, Tran Thi Hong, Mai, Pham Phuong, Phong, Nguyen Duy, Dung, Nguyen Thi, Chuong, Ly Van, Lee, Sue J, Caws, M, de Jong, Menno D, Hien, Tran Tinh, Farrar, Jeremy J

“…The aim of this prospective, observational cohort study was to determine the clinical and microbiological features, outcome, and baseline variables predictive…”
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Prognostic Models for 9-Month Mortality in Tuberculous Meningitis by Thao, Le Thi Phuong, Heemskerk, A Dorothee, Geskus, Ronald B, Mai, Nguyen Thi Hoang, Ha, Dang Thi Minh, Chau, Tran Thi Hong, Phu, Nguyen Hoan, Chau, Nguyen Van Vinh, Caws, Maxine, Lan, Nguyen Huu, Thu, Do Dang Anh, Thuong, Nguyen Thuy Thuong, Day, Jeremy, Farrar, Jeremy J, Torok, M Estee, Bang, Nguyen Duc, Thwaites, Guy E, Wolbers, Marcel

“…Tuberculous meningitis (TBM) is the most severe form of extrapulmonary tuberculosis. We developed and validated prognostic models for 9-month mortality in…”
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Genomic surveillance reveals low prevalence of livestock-associated methicillin-resistant Staphylococcus aureus in the East of England by Harrison, Ewan M., Coll, Francesc, Toleman, Michelle S., Blane, Beth, Brown, Nicholas M., Török, M. Estee, Parkhill, Julian, Peacock, Sharon J.

“…Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) is an emerging problem in many parts of the world. LA-MRSA has been isolated…”
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Multi-Compartment Profiling of Bacterial and Host Metabolites Identifies Intestinal Dysbiosis and Its Functional Consequences in the Critically Ill Child by Wijeyesekera, Anisha, Wagner, Josef, De Goffau, Marcus, Thurston, Sarah, Rodrigues Sabino, Adilson, Zaher, Sara, White, Deborah, Ridout, Jenna, Peters, Mark J., Ramnarayan, Padmanabhan, Branco, Ricardo G., Torok, M. Estee, Valla, Frederic, Meyer, Rosan, Klein, Nigel, Frost, Gary, Parkhill, Julian, Holmes, Elaine, Pathan, Nazima

“…OBJECTIVES:Adverse physiology and antibiotic exposure devastate the intestinal microbiome in critical illness. Time and cost implications limit the immediate…”
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Clonal differences in Staphylococcus aureus bacteraemia-associated mortality by Recker, Mario, Laabei, Maisem, Toleman, Michelle S., Reuter, Sandra, Saunderson, Rebecca B., Blane, Beth, Török, M. Estee, Ouadi, Khadija, Stevens, Emily, Yokoyama, Maho, Steventon, Joseph, Thompson, Luke, Milne, Gregory, Bayliss, Sion, Bacon, Leann, Peacock, Sharon J., Massey, Ruth C.

“…The bacterium Staphylococcus aureus is a major human pathogen for which the emergence of antibiotic resistance is a global public health concern. Infection…”
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Effective control of SARS-CoV-2 transmission between healthcare workers during a period of diminished community prevalence of COVID-19 by Jones, Nick K, Rivett, Lucy, Sparkes, Dominic, Forrest, Sally, Sridhar, Sushmita, Young, Jamie, Pereira-Dias, Joana, Cormie, Claire, Gill, Harmeet, Reynolds, Nicola, Wantoch, Michelle, Routledge, Matthew, Warne, Ben, Levy, Jack, Córdova Jiménez, William David, Samad, Fathima Nisha Begum, McNicholas, Chris, Ferris, Mark, Gray, Jane, Gill, Michael, Curran, Martin D, Fuller, Stewart, Chaudhry, Afzal, Shaw, Ashley, Bradley, John R, Hannon, Gregory J, Goodfellow, Ian G, Dougan, Gordon, Smith, Kenneth Gc, Lehner, Paul J, Wright, Giles, Matheson, Nicholas J, Baker, Stephen, Weekes, Michael P

“…Previously, we showed that 3% (31/1032)of asymptomatic healthcare workers (HCWs) from a large teaching hospital in Cambridge, UK, tested positive for…”
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