Search Results - "Torocsik, D."

Detection of factor XIII-A is a valuable tool for distinguishing dendritic cells and tissue macrophages in granuloma annulare and necrobiosis lipoidica by Töröcsik, D., Bárdos, H., Hatalyák, Zs, Dezső, B., Losonczy, G., Paragh, L., Péter, Z., Balázs, M., Remenyik, E., Ádány, R.

“…Background Factor XIII subunit A (FXIII‐A) is used as a diagnostic marker in a wide range of dermatological diseases ranging from inflammatory lesions to…”
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Sebocytes contribute to skin inflammation by promoting the differentiation of T helper 17 cells by Mattii, M., Lovászi, M., Garzorz, N., Atenhan, A., Quaranta, M., Lauffer, F., Konstantinow, A., Küpper, M., Zouboulis, C.C., Kemeny, L., Eyerich, K., Schmidt‐Weber, C.B., Törőcsik, D., Eyerich, S.

“…Summary Background The main function of sebocytes is considered to be the production of lipids to moisturize the skin. However, it recently became apparent…”
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Sebum lipids influence macrophage polarization and activation by Lovászi, M., Mattii, M., Eyerich, K., Gácsi, A., Csányi, E., Kovács, D., Rühl, R., Szegedi, A., Kemény, L., Ståhle, M., Zouboulis, C.C., Eyerich, S., Törőcsik, D.

“…Summary Background As lipids are known to regulate macrophage functions, it is reasonable to suppose that a sebocyte–macrophage axis mediated by sebum lipids…”
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Primary alterations during the development of hidradenitis suppurativa by Dajnoki, Z., Somogyi, O., Medgyesi, B., Jenei, A., Szabó, L., Gáspár, K., Hendrik, Z., Gergely, P., Imre, D., Póliska, S., Törőcsik, D., Zouboulis, C.C., Prens, E.P., Kapitány, A., Szegedi, A.

“…Background Hidradenitis suppurativa (HS) is a chronic, inflammatory disease of the apocrine gland‐rich (AGR) skin region. The initial steps of disease…”
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Leptin promotes a proinflammatory lipid profile and induces inflammatory pathways in human SZ95 sebocytes by Törőcsik, D., Kovács, D., Camera, E., Lovászi, M., Cseri, K., Nagy, G.G., Molinaro, R., Rühl, R., Tax, G., Szabó, K., Picardo, M., Kemény, L., Zouboulis, C.C., Remenyik, É.

“…Summary Background Leptin, the adipocyte‐secreted hormone that regulates weight, is known to link lipid metabolism with inflammation in various cell types…”
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Isotretinoin is indirectly effective in sebocytes by Kovács, D., Hegyi, K., Szegedi, A., Deák, D., Póliska, Sz, Rühl, R., Zouboulis, C.C., Törőcsik, D.

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Identification of factor XIII-A as a marker of alternative macrophage activation by Töröcsik, D, Bárdos, H, Nagy, L, Adány, R

“…Factor XIII subunit A of blood coagulation (FXIII-A) is known to be synthesized but not secreted by the monocyte/macrophage cell line. On the basis of its…”
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Apocrine Gland–Rich Skin Has a Non-Inflammatory IL-17–Related Immune Milieu, that Turns to Inflammatory IL-17–Mediated Disease in Hidradenitis Suppurativa by Jenei, A., Dajnoki, Z., Medgyesi, B., Gáspár, K., Béke, G., Kinyó, Á., Méhes, G., Hendrik, Z., Dinya, T., Törőcsik, D., Zouboulis, C.C., Prens, E.P., Bíró, T., Szegedi, A., Kapitány, A.

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711 Barrier function related genes and proteins are altered in acne involved skin by Dull, K., Fedor-Lénárt, K., Dajnoki, Z., Póliska, S., Hendrik, Z., Szegedi, A., Torocsik, D.

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1329 Transglutaminase 2 deficiency leads to lipid accumulation and reduced autophagy in SZ95 sebocytes by Fedor-Lénárt, K., Kovács, D., Demény, M., Újlaki, G., Zouboulis, C.C., Szegedi, A., Torocsik, D.

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Sebum lipids influence macrophage polarization and activation by Lovászi, M., Mattii, M., Eyerich, K., Gácsi, A., Csányi, E., Kovács, D., Rühl, R., Szegedi, A., Kemény, L., Ståhle, M., Zouboulis, C.C., Eyerich, S., Törőcsik, D.

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Sebocytes contribute to skin inflammation by promoting the differentiation of T helper 17 cells by Mattii, M., Lovászi, M., Garzorz, N., Atenhan, A., Quaranta, M., Lauffer, F., Konstantinow, A., Küpper, M., Zouboulis, C.C., Kemeny, L., Eyerich, K., Schmidt‐Weber, C.B., Törőcsik, D., Eyerich, S.

“…Summary The main function of cells in the skin called sebocytes is considered to be the production of lipids (oils) to moisturize the skin. It used to be…”
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Steroid concentrations in patients with atopic dermatitis: reduced plasma dehydroepiandrosterone sulfate and increased cortisone levels by Mihály, J., Sonntag, D., Krebiehl, G., Szegedi, A., Töröcsik, D., Rühl, R.

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PPARγ in immunity and inflammation: cell types and diseases by Széles, Lajos, Töröcsik, Dániel, Nagy, László

“…The lipid activated transcription factor, PPARγ appears to have multiple functions in the immune system. There are several cell types expressing the receptor,…”
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Sebaceous glands actively contribute to distinct immune response patterns in atopic dermatitis and psoriasis by Seiringer, P, Hillig, C, Biedermann, T, Zouboulis, CC, Menden, M, Eyerich, K, Torocsik, D

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Genome wide analysis of TLR1/2- and TLR4-activated SZ95 sebocytes reveals a complex immune-competence and identifies serum amyloid A as a marker for activated sebaceous glands by Törőcsik, Dániel, Kovács, Dóra, Póliska, Szilárd, Szentkereszty-Kovács, Zita, Lovászi, Marianna, Hegyi, Katalin, Szegedi, Andrea, Zouboulis, Christos C, Ståhle, Mona

“…Toll-like receptors (TLR) 2 and 4 are active in sebaceous glands and play a central role in the development of acne. Still, there is only limited knowledge on…”
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215 TLR2 and TLR4 activated SZ95 sebocytes promote inflammation prior to changing lipid metabolism at the level of gene expression by Torocsik, D., Poliska, S., Kovacs, D., Lovászi, M., Kovacs, Z., Zouboulis, C., Ståhle, M.

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412 Characterization of the immunomodulatory effects of sebocytes on macrophages by Lovászi, M., Mattii, M., Eyerich, K., Kovacs, D., Zouboulis, C., Ståhle, M., Eyerich, S., Torocsik, D.

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Spatial transcriptomics reveals altered lipid metabolism and inflammation-related gene expression of sebaceous glands in psoriasis and atopic dermatitis by Seiringer, Peter, Hillig, Christina, Schäbitz, Alexander, Jargosch, Manja, Pilz, Anna Caroline, Eyerich, Stefanie, Szegedi, Andrea, Sochorová, Michaela, Gruber, Florian, Zouboulis, Christos C, Biedermann, Tilo, Menden, Michael P, Eyerich, Kilian, Törőcsik, Daniel

“…Sebaceous glands drive acne, however, their role in other inflammatory skin diseases remains unclear. To shed light on their potential contribution to disease…”
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447 Sebaceous gland-rich skin is characterized by TSLP expression and distinct immune surveillance which is disturbed in rosacea by Dajnoki, Z., Béke, G., Kapitány, A., Gáspár, K., Hendrik, Z., Juhász, I., Zouboulis, C.C., Bácsi, A., Bíró, T., Torocsik, D., Szegedi, A.

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