Search Results - "Toris, C B"

Pharmacotherapies for glaucoma by Toris, C B

“…Glaucoma is a group of progressive optic neuropathies in which the axons in the optic nerve are injured, retinal ganglion cell numbers are reduced and vision…”
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The affinity, intrinsic activity and selectivity of a structurally novel EP2 receptor agonist at human prostanoid receptors by Coleman, R A, Woodrooffe, A J, Clark, K L, Toris, C B, Fan, S, Wang, J W, Woodward, D F

“…Background and Purpose Prostanoid EP2 receptor agonists exhibit several activities including ocular hypotension, tocolysis and anti‐inflammatory activity. This…”
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The affinity, intrinsic activity and selectivity of a structurally novel EP 2 receptor agonist at human prostanoid receptors by Coleman, R A, Woodrooffe, A J, Clark, K L, Toris, C B, Fan, S, Wang, J W, Woodward, D F

“…Prostanoid EP receptor agonists exhibit several activities including ocular hypotension, tocolysis and anti-inflammatory activity. This report describes the…”
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Acute versus chronic effects of Brimonidine on aqueous humor dynamics in ocular hypertensive patients by TORIS, C. B, CAMRAS, C. B, YABLONSKI, M. E

“…To report the acute vs chronic effects of brimonidine, a selective alpha2-adrenergic receptor agonist, on aqueous humor dynamics in ocular hypertensive…”
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Aqueous humor dynamics in the aging human eye by Toris, Carol B, Yablonski, Michael E, Wang, Yun-Liang, Camras, Carl B

“…Purpose: Healthy subjects were recruited to identify normal, age-associated changes in intraocular pressure and aqueous humor dynamics. Methods: Normal healthy…”
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Effects of exogenous prostaglandins on aqueous humor dynamics and blood-aqueous barrier function by Toris, Carol B., Camras, Carl B., Yablonski, Michael E., Brubaker, Richard F.

“…Topical prostaglandins (PGs) are very effective at reducing intraocular pressure (IOP) in a variety of animals and in humans with relatively few side effects…”
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Potential mechanism for the additivity of pilocarpine and latanoprost by Toris, Carol B, Zhan, Gui-Lin, Zhao, Jian, Camras, Carl B, Yablonski, Michael E

“…PURPOSE: To determine the ocular hypotensive mechanism underlying the additivity of latanoprost and pilocarpine. METHODS: This randomized, double-masked study…”
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Hydrostatic pressure of the suprachoroidal space by Emi, K, Pederson, JE, Toris, CB

“…The hydrostatic pressure of the suprachoroidal space was measured in 18 cynomolgus monkey eyes by one of two methods: (1) direct cannulation, or (2) silicone…”
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Effects of apraclonidine on aqueous humor dynamics in human eyes by Toris, C B, Tafoya, M E, Camras, C B, Yablonski, M E

“…The mechanism by which apraclonidine, an alpha 2-adrenergic agonist, lowers intraocular pressure (IOP) was evaluated in humans. In a randomized, double-masked,…”
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Efficacy and adverse effects of medications used in the treatment of glaucoma by CAMRAS, C. B, TORIS, C. B, TAMESIS, R. R

“…With the advent of several new topically active medications for glaucoma therapy, intraocular pressure (IOP) can be reduced to target levels in more patients…”
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Aqueous humor dynamics in experimental iridocyclitis by Toris, CB, Pederson, JE

“…Ocular inflammation was induced by intravitreal bovine serum albumin (BSA) injection in one eye of each of six cynomolgus monkeys. The fellow eyes were…”
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Aqueous humor dynamics in monkeys with laser-induced glaucoma by Toris, C B, Zhan, G L, Wang, Y L, Zhao, J, McLaughlin, M A, Camras, C B, Yablonski, M E

“…This study determines the effects of laser-induced glaucoma on aqueous humor dynamics of 18 cynomolgus monkeys. Baseline measurements of 12 monkeys included…”
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Effects of Topical Epinephrine on Aqueous Humor Dynamics in the Cat by WANG, YUN-LIANG, TORIS, CAROL B., ZHAN, GUILIN, YABLONSKI, MICHAEL E.

“…The purpose of this study was to investigate, in cats, the effects of topical epinephrine on aqueous humor dynamics as measured by the non-invasive method of…”
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Effect of intraocular pressure on uveoscleral outflow following cyclodialysis in the monkey eye by TORIS, C. B, PEDERSON, J. E

“…Cyclodialysis was performed in both eyes of five cynomolgus monkeys. Two days later the intraocular pressure (IOP) had fallen from 17.7 +/- 0.8 to 7.1 +/- 1.4…”
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Extravascular albumin concentration of the uvea by Toris, CB, Pederson, JE, Tsuboi, S, Gregerson, DS, Rice, TJ

“…The hypothesis that uveal vessels absorb fluid was tested by measuring the albumin in extravascular uveal tissues and in plasma. From these results the…”
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Uveoscleral outflow following cyclodialysis in the monkey eye using a fluorescent tracer by Suguro, K, Toris, CB, Pederson, JE

“…Cyclodialysis was performed in one eye of each of eight cynomolgus monkeys. Two days later, the intraocular pressure was 1.6 +/- 0.7 mmHg in eyes with…”
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Uveoscleral outflow: diffusion or flow? by PEDERSON, J. E, TORIS, C. B

“…Shallow peripheral ciliochoroidal detachments with 10(-4) M fluorescein isothiocyanate dextran 70 were created in cynomolgus monkey eyes. Anterior chamber…”
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Functional recovery of retinal pigment epithelial damage in experimental retinal detachment by Tsuboi, S, Pederson, JE, Toris, CB

“…The integrity of the RPE barrier function in retinal detachment was studied in vitro. The retinal pigment epithelium (RPE)-choroid tissue was isolated from…”
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Prostaglandin A2 increases uveoscleral outflow and trabecular outflow facility in the cat by TORIS, C. B, YABLONSKI, M. E, YUN-LIANG WANG, HAYASHI, M

“…Prostaglandins (PG) are very effective ocular hypotensive agents. It is generally agreed that these drugs reduce intraocular pressure primarily by increasing…”
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Effects of brimonidine on aqueous humor dynamics in human eyes by Toris, C B, Gleason, M L, Camras, C B, Yablonski, M E

“…To evaluate the mechanism by which brimonidine, a selective alpha 2-adrenergic agonist, lowers intraocular pressure (IOP) in humans. Twenty-one volunteers with…”
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