Search Results - "Torchen, Laura C"

Increased antimüllerian hormone levels and other reproductive endocrine changes in adult male relatives of women with polycystic ovary syndrome by Torchen, Laura C., M.D, Kumar, Ajay, Ph.D, Kalra, Bhanu, Ph.D, Savjani, Gopal, B.S, Sisk, Ryan, B.S, Legro, Richard S., M.D, Dunaif, Andrea, M.D

“…Objective To investigate for differences in reproductive hormone levels in male relatives of women with polycystic ovary syndrome (PCOS). Design…”
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Cardiometabolic Risk in PCOS: More than a Reproductive Disorder by Torchen, Laura C.

“…Purpose of Review Polycystic ovary syndrome (PCOS) is diagnosed by its characteristic reproductive features. However, PCOS is also associated with metabolic…”
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Early phenotypes in polycystic ovary syndrome: some answers, more questions by Torchen, Laura C.

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Distinctive Reproductive Phenotypes in Peripubertal Girls at Risk for Polycystic Ovary Syndrome by Torchen, Laura C, Legro, Richard S, Dunaif, Andrea

“…Abstract Context Increased testosterone (T) levels are a cardinal feature of polycystic ovary syndrome (PCOS). Female relatives of affected women, including…”
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Response to Letter to the Editor from de Zegher and Ibáñez: "Distinct Reproductive Phenotypes Segregate With Differences in Body Weight in Adolescent Polycystic Ovary Syndrome" by Torchen, Laura C

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11-Oxygenated C19 Steroids Do Not Distinguish the Hyperandrogenic Phenotype of PCOS Daughters from Girls with Obesity by Torchen, Laura C, Sisk, Ryan, Legro, Richard S, Turcu, Adina F, Auchus, Richard J, Dunaif, Andrea

“…Abstract Context Hyperandrogenemia (HA) is a consistent reproductive phenotype in women with polycystic ovary syndrome (PCOS) and their relatives. Increased…”
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Adjusting antimüllerian hormone levels for age and body mass index improves detection of polycystic ovary syndrome by Palomaki, Glenn E., Kalra, Bhanu, Kumar, Tanya, Patel, Amita S., Savjani, Gopal, Torchen, Laura C., Dunaif, Andrea, Morrison, Anthony, Lambert-Messerlian, Geralyn M., Kumar, Ajay

“…To examine whether accounting for a woman’s age and body mass index (BMI) would improve the ability of antimüllerian hormone (AMH) to distinguish between women…”
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Persistent Apparent Pancreatic β-Cell Defects in Premenarchal PCOS Relatives by Torchen, Laura C, Fogel, Naomi R, Brickman, Wendy J, Paparodis, Rodis, Dunaif, Andrea

“…Context: Polycystic ovary syndrome confers an increased risk for type 2 diabetes in affected women as early as adolescence. First-degree relatives (FDRs) of…”
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Hyperandrogenemia is Common in Asymptomatic Women and is Associated with Increased Metabolic Risk by Torchen, Laura C., Tsai, Joy N., Jasti, Prathima, Macaya, Rodrigo, Sisk, Ryan, Dapas, Matthew L., Hayes, M. Geoffrey, Urbanek, Margrit, Dunaif, Andrea

“…Objective Women with metabolic syndrome (MetS) have higher endogenous testosterone (T) levels than unaffected women. This study investigated whether…”
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Evidence for Increased 5α-Reductase Activity During Early Childhood in Daughters of Women With Polycystic Ovary Syndrome by Torchen, Laura C, Idkowiak, Jan, Fogel, Naomi R, O'Neil, Donna M, Shackleton, Cedric H. L, Arlt, Wiebke, Dunaif, Andrea

“…Context: Polycystic ovary syndrome (PCOS) is a heritable, complex genetic disease. Animal models suggest that androgen exposure at critical developmental…”
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Distinct Reproductive Phenotypes Segregate With Differences in Body Weight in Adolescent Polycystic Ovary Syndrome by Chen-Patterson, Angie, Bernier, Angelina, Burgert, Tania, Davis, Vanessa, Khan, Tazeena, Geller, David, Paprocki, Emily, Shah, Rachana, Witchel, Selma F, Pereira-Eshraghi, Camila, Sopher, Aviva B, Cree, Melanie G, Torchen, Laura C

“…Polycystic ovary syndrome (PCOS) is a heterogenous clinical syndrome defined by hyperandrogenism and irregular menses. In adult women with PCOS, discrete…”
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Intranasal Carbetocin Reduces Hyperphagia, Anxiousness, and Distress in Prader-Willi Syndrome: CARE-PWS Phase 3 Trial by Roof, Elizabeth, Deal, Cheri L, McCandless, Shawn E, Cowan, Ronald L, Miller, Jennifer L, Hamilton, Jill K, Roeder, Elizabeth R, McCormack, Shana E, Roshan Lal, Tamanna R, Abdul-Latif, Hussein D, Haqq, Andrea M, Obrynba, Kathryn S, Torchen, Laura C, Vidmar, Alaina P, Viskochil, David H, Chanoine, Jean-Pierre, Lam, Carol K L, Pierce, Melinda J, Williams, Laurel L, Bird, Lynne M, Butler, Merlin G, Jensen, Diane E, Myers, Susan E, Oatman, Oliver J, Baskaran, Charumathi, Chalmers, Laura J, Fu, Cary, Alos, Nathalie, McLean, Scott D, Shah, Ajay, Whitman, Barbara Y, Blumenstein, Brent A, Leonard, Sarah F, Ernest, Jessica P, Cormier, Joseph W, Cotter, Sara P, Ryman, Davis C

“…Abstract Context Prader-Willi syndrome (PWS) is a rare genetic disorder characterized by endocrine and neuropsychiatric problems including hyperphagia,…”
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LBMON237 Predictors Of Postmenarchal Progression Of Pcos Phenotypes In At-risk Girls by Torchen, Laura C, Aekka, Apoorva, Ratnam, Sarayu, Brewer, Kelly, Islam, Sabah, Li, Chun, Dunaif, Andrea

“…Physiologic and genetic analyses implicate hyperandrogenemia (HA) as a core causal pathway in PCOS. Both daughters of women with PCOS (PCOS-d) and…”
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Increased Anti-Müllerian Hormone Levels and Other Reproductive Endocrine Changes in Adult Male Relatives of Women with Polycystic Ovary Syndrome by Torchen, Laura C, Kumar, Ajay, Kalra, Bhanu, Savjani, Gopal, Sisk, Ryan, Legro, Richard S., Dunaif, Andrea

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OR33-03 Congenital Leptin Deficiency: Clinical Insights from the First Reported US Cases by Torchen, Laura C, Hakamy, Beth, Gordon, Leo I, Marsh, Erica E, Yaseen, Nabeel R, Neff, Lisa M

“…Background: Congenital leptin deficiency (CLD) is a rare autosomal recessive form of monogenic obesity caused by loss-of-function mutations in the leptin gene…”
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