Search Results - "Toraño, G"

Aberrant DNA methylation patterns of spermatozoa in men with unexplained infertility by Urdinguio, Rocío G., Bayón, Gustavo F., Dmitrijeva, Marija, Toraño, Estela G., Bravo, Cristina, Fraga, Mario F., Bassas, Lluís, Larriba, Sara, Fernández, Agustín F.

“…STUDY QUESTION Are there DNA methylation alterations in sperm that could explain the reduced biological fertility of male partners from couples with…”
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Global DNA hypomethylation in cancer: review of validated methods and clinical significance by Toraño, Estela G, Petrus, Sandra, Fernandez, Agustin F, Fraga, Mario F

“…Abstract DNA methylation is one of the best-known epigenetic modifications in mammals. The alteration of DNA methylation patterns has been found to be related…”
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H3K4me1 marks DNA regions hypomethylated during aging in human stem and differentiated cells by Fernández, Agustín F, Bayón, Gustavo F, Urdinguio, Rocío G, Toraño, Estela G, García, María G, Carella, Antonella, Petrus-Reurer, Sandra, Ferrero, Cecilia, Martinez-Camblor, Pablo, Cubillo, Isabel, García-Castro, Javier, Delgado-Calle, Jesús, Pérez-Campo, Flor M, Riancho, José A, Bueno, Clara, Menéndez, Pablo, Mentink, Anouk, Mareschi, Katia, Claire, Fabian, Fagnani, Corrado, Medda, Emanuela, Toccaceli, Virgilia, Brescianini, Sonia, Moran, Sebastián, Esteller, Manel, Stolzing, Alexandra, de Boer, Jan, Nisticò, Lorenza, Stazi, Maria A, Fraga, Mario F

“…In differentiated cells, aging is associated with hypermethylation of DNA regions enriched in repressive histone post-translational modifications. However, the…”
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Combination lenalidomide‐rituximab immunotherapy activates anti‐tumour immunity and induces tumour cell death by complementary mechanisms of action in follicular lymphoma by Chiu, Hsiling, Trisal, Preeti, Bjorklund, Chad, Carrancio, Soraya, Toraño, Estela G., Guarinos, Carla, Papazoglou, Despoina, Hagner, Patrick R., Beldi‐Ferchiou, Asma, Tarte, Karin, Delfau‐Larue, Marie‐Hélène, Morschhauser, Franck, Ramsay, Alan G., Gandhi, Anita K.

“…Summary Chemotherapy plus rituximab has been the mainstay of treatment for follicular lymphoma (FL) for two decades but is associated with immunosuppression…”
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Age-associated hydroxymethylation in human bone-marrow mesenchymal stem cells by Toraño, Estela G, Bayón, Gustavo F, Del Real, Álvaro, Sierra, Marta I, García, María G, Carella, Antonella, Belmonte, Thalia, Urdinguio, Rocío G, Cubillo, Isabel, García-Castro, Javier, Delgado-Calle, Jesús, Pérez-Campo, Flor M, Riancho, José A, Fraga, Mario F, Fernández, Agustín F

“…Age-associated changes in genomic DNA methylation have been primarily attributed to 5-methylcytosine (5mC). However, the recent discovery of…”
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A DNA methylation signature associated with the epigenetic repression of glycine N-methyltransferase in human hepatocellular carcinoma by Huidobro, Covadonga, Toraño, Estela G., Fernández, Agustín F., Urdinguio, Rocío G., Rodríguez, Ramón M., Ferrero, Cecilia, Martínez-Camblor, Pablo, Boix, Loreto, Bruix, Jordi, García-Rodríguez, Juan Luís, Varela-Rey, Marta, Mato, José María, Martínez-Chantar, María Luz, Fraga, Mario F.

“…The basic mechanisms underlying promoter DNA hypermethylation in cancer are still largely unknown. It has been proposed that the levels of the methyl donor…”
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Role of BRD4 in hematopoietic differentiation of embryonic stem cells by Rodriguez, Ramon M, Suarez-Alvarez, Beatriz, Salvanés, Ruben, Huidobro, Covadonga, Toraño, Estela G, Garcia-Perez, Jose L, Lopez-Larrea, Carlos, Fernandez, Agustin F, Bueno, Clara, Menendez, Pablo, Fraga, Mario F

“…The bromodomain and extra terminal (BET) protein family member BRD4 is a transcriptional regulator, critical for cell cycle progression and cellular viability…”
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The Impact of External Factors on the Epigenome: In Utero and over Lifetime by Torano, Estela G, Garcia, Marla G, Fernandez-Morera, Juan Luis, Nino-Garcia, Pilar, Fernandez, Agustin F

“…Epigenetic marks change during fetal development, adult life, and aging. Some changes play an important role in the establishment and regulation of gene…”
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Loss of 5hmC identifies a new type of aberrant DNA hypermethylation in glioma by Fernandez, Agustin F, Bayón, Gustavo F, Sierra, Marta I, Urdinguio, Rocio G, Toraño, Estela G, García, Maria G, Carella, Antonella, López, Virginia, Santamarina, Pablo, Pérez, Raúl F, Belmonte, Thalía, Tejedor, Juan Ramon, Cobo, Isabel, Menendez, Pablo, Mangas, Cristina, Ferrero, Cecilia, Rodrigo, Luis, Astudillo, Aurora, Ortea, Ignacio, Cueto Díaz, Sergio, Rodríguez-Gonzalez, Pablo, García Alonso, J Ignacio, Mollejo, Manuela, Meléndez, Bárbara, Domínguez, Gemma, Bonilla, Felix, Fraga, Mario F

“…Abstract Aberrant DNA hypermethylation is a hallmark of cancer although the underlying molecular mechanisms are still poorly understood. To study the possible…”
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Corrigendum: H3K4me1 marks DNA regions hypomethylated during aging in human stem and differentiated cells by Fernández, Agustín F, Bayón, Gustavo F, Urdinguio, Rocío G, Toraño, Estela G, García, María G, Carella, Antonella, Petrus-Reurer, Sandra, Ferrero, Cecilia, Martinez-Camblor, Pablo, Cubillo, Isabel, García-Castro, Javier, Delgado-Calle, Jesús, Pérez-Campo, Flor M, Riancho, José A, Bueno, Clara, Menéndez, Pablo, Mentink, Anouk, Mareschi, Katia, Claire, Fabian, Fagnani, Corrado, Medda, Emanuela, Toccaceli, Virgilia, Brescianini, Sonia, Moran, Sebastián, Esteller, Manel, Stolzing, Alexandra, de Boer, Jan, Nisticò, Lorenza, Stazi, Maria A, Fraga, Mario F

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LINE-1 methylation in leukocyte DNA, interaction with phosphatidylethanolamine N-methyltransferase variants and bladder cancer risk by Tajuddin, S M, Amaral, A F S, Fernández, A F, Chanock, S, Silverman, D T, Tardón, A, Carrato, A, García-Closas, M, Jackson, B P, Toraño, E G, Márquez, M, Urdinguio, R G, García-Closas, R, Rothman, N, Kogevinas, M, Real, F X, Fraga, M F, Malats, N

“…Background: Aberrant global DNA methylation is shown to increase cancer risk. LINE-1 has been proven a measure of global DNA methylation. The objectives of…”
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Nasal carriers of methicillin-resistant Staphylococcus aureus among cuban children attending day-care centers by Toraño, G, Quiñones, D, Hernández, I, Hernández, T, Tamargo, I, Borroto, S

“…Recent but scarce reports of methicillin-resistant Staphylococcus aureus strains (MRSA) among children without risk factors associated with its acquisition…”
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Laboratory-based surveillance of Neisseria meningitidis isolates from disease cases in Latin American and Caribbean countries, SIREVA II 2006-2010 by Ibarz-Pavón, Ana Belén, Lemos, Ana Paula, Gorla, Maria Cecilia, Regueira, Mabel, Gabastou, Jean-Marc

“…Published data on the epidemiology of meningococcal disease in Latin America and the Caribbean region is scarce and, when available, it is often published in…”
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Characterization of Haemophilus influenzae obtained from invasive diseases in Cuban children under five years of age by Tamargo, I, Toraño, G, Rodriguez, O, Perez, M, Llop, A

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A Synthetic Conjugate Polysaccharide Vaccine against Haemophilus Influenzae Type B by Verez-Bencomo, V., Fernández-Santana, V., Hardy, Eugenio, Toledo, Maria E., Rodríguez, Maria C., Heynngnezz, Lazaro, Rodriguez, Arlene, Baly, Alberto, Herrera, Luis, Izquierdo, Mabel, Villar, Annette, Valdés, Yury, Cosme, Karelia, Deler, Mercedes L., Montane, Manuel, Garcia, Ernesto, Ramos, Alexis, Aguilar, Aristides, Medina, Ernesto, Toraño, Gilda, Sosa, Iván, Hernandez, Ibis, Martínez, Raydel, Muzachio, Alexis, Carmenates, Ania, Costa, Lourdes, Cardoso, Félix, Campa, Concepción, Diaz, Manuel, Roy, René

“…Glycoconjugate vaccines provide effective prophylaxis against bacterial infections. To date, however, no commercial vaccine has been available in which the key…”
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Methicillin-resistant Staphylococcus aureus without borders: USA300 in Cuba by Hopman, J, Peraza, G Toraño, Espinosa, F, Klaassen, CH, Velázquez, DM, Meis, JF, Voss, A

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Nasopharyngeal colonisation by Streptococcus pneumoniae in Cuban preschool children: Cross-sectional surveys before/after pneumococcal vaccination by Chávez Amaro, D.M., Linares-Pérez, N., Casanova González, M.F., Toledo-Romaní, M.E., Rodríguez Valladares, N.N., Rodríguez Noda, L.M., Mirabal Sosa, M., Rodríguez González, M.C., Toraño Peraza, G., García-Rivera, D., Valdés-Balbín, Y., Vérez-Bencomo, V.

“…Nasopharyngeal colonisation (CNF) is considered a “major point” in the evaluation of pneumococal conjugate vaccines (PCVs). A year after the administration of…”
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Colonización nasofaríngea por Streptococus pneumoniae en niños prescolares cubanos: encuestas transversales antes-después de la vacunación antineumocócica by Chávez Amaro, D.M., Linares-Pérez, N., Casanova González, M.F., Toledo-Romaní, M.E., Rodríguez Valladares, N.N., Rodríguez Noda, L.M., Mirabal Sosa, M., Rodríguez González, M.C., Toraño Peraza, G., García-Rivera, D., Valdés-Balbín, Y., Vérez-Bencomo, V.

“…La colonización nasofaríngea (CNF) constituye un «endpoint» principal en la evaluación de vacunas conjugadas antineumocócicas (PCV). Un año posterior a la…”
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Nasopharyngeal Colonization by Moraxella catarrhalis and Study of Antimicrobial Susceptibility in Healthy Children from Cuban Day-Care Centers by Quiñones, Dianelys, Llanes, Rafael, Toraño, Gilda, Pérez, Miriam

“…The prevalence of nasopharyngeal carriage of Moraxella catarrhalis was determined for the first time in Cuba. One-hundred fifty healthy children attending…”
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A novel immunization schedule for obtaining anti-LPS Haemophilus influenzae type b antibodies by Falcón Márquez, R, Toraño Peraza, G, Victoria Martínez, B, Tamargo Martínez, I

“…A novel immunization schedule was tested to increase antibodies to Haemophilus influenzae type B in which a 0.5% formaldehyde-inactivated cellular antigen and…”
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