Search Results - "Tora, L"

Distinct GCN5 PCAF-containing complexes function as co-activators and are involved in transcription factor and global histone acetylation by Nagy, Z, Tora, L

“…Transcription in eukaryotes is a tightly regulated, multistep process. Gene-specific transcriptional activators, several different co-activators and general…”
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TAF15 is important for cellular proliferation and regulates the expression of a subset of cell cycle genes through miRNAs by Ballarino, M, Jobert, L, Dembélé, D, de la Grange, P, Auboeuf, D, Tora, L

“…TAF15 (formerly TAFII68) is a member of the FET (FUS, EWS, TAF15) family of RNA- and DNA-binding proteins whose genes are frequently translocated in sarcomas…”
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Genes of the Ecdysone Biosynthesis Pathway Are Regulated by the dATAC Histone Acetyltransferase Complex in Drosophila by Pankotai, T, Popescu, C, Martin, D, Grau, B, Zsindely, N, Bodai, L, Tora, L, Ferrus, A, Boros, I

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Transcriptional alterations and chromatin remodeling in polyglutamine diseases by Helmlinger, Dominique, Tora, Làszlò, Devys, Didier

“…Transcriptional dysregulation is now thought to be a common feature of polyglutamine disorders, including the spinocerebellar ataxias (SCAs). However, the…”
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Function of TAF(II)-containing complex without TBP in transcription by RNA polymerase II by Wieczorek, E, Brand, M, Jacq, X, Tora, L

“…Initiation of transcription of a gene from a core promoter region by RNA polymerase II requires the assembly of several initiation factors to form a…”
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The N‐terminal part of TIF1, a putative mediator of the ligand‐dependent activation function (AF‐2) of nuclear receptors, is fused to B‐raf in the oncogenic protein T18 by Le Douarin, B., Zechel, C., Garnier, J.M., Lutz, Y., Tora, L., Pierrat, P., Heery, D., Gronemeyer, H., Chambon, P., Losson, R.

“…Nuclear receptors (NRs) bound to response elements mediate the effects of cognate ligands on gene expression. Their ligand‐dependent activation function, AF‐2,…”
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Two distinct estrogen‐regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B by Kastner, P., Krust, A., Turcotte, B., Stropp, U., Tora, L., Gronemeyer, H., Chambon, P.

“…The human progesterone receptor (hPR) cDNA, synthesized from T47D breast cancer cells, and the hPR gene 5′‐flanking region were cloned and sequenced…”
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hTAF(II)68, a novel RNA/ssDNA‐binding protein with homology to the pro‐oncoproteins TLS/FUS and EWS is associated with both TFIID and RNA polymerase II by Bertolotti, A., Lutz, Y., Heard, D. J., Chambon, P., Tora, L.

“…TFIID is the main sequence‐specific DNA‐binding component of the RNA polymerase II (Pol II) transcriptional machinery. It is a multiprotein complex composed of…”
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Intronic enhancers control expression of zebrafish sonic hedgehog in floor plate and notochord by Müller, F, Chang, B, Albert, S, Fischer, N, Tora, L, Strähle, U

“…The signalling molecule Sonic hedgehog (Shh) controls a wide range of differentiation processes during vertebrate development. Numerous studies have suggested…”
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loss of histone H3 lysine 9 acetylation due to dSAGA-specific dAda2b mutation influences the expression of only a small subset of genes by Zsindely, Nóra, Pankotai, Tibor, Újfaludi, Zsuzsanna, Lakatos, Dániel, Komonyi, Orbán, Bodai, László, Tora, László, Boros, Imre M

“…In Drosophila, the dADA2b-containing dSAGA complex is involved in histone H3 lysine 9 and 14 acetylation. Curiously, although the lysine 9- and 14-acetylated…”
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Functional interference between hypoxia and dioxin signal transduction pathways: competition for recruitment of the Arnt transcription factor by Gradin, Katarina, McGuire, Jacqueline, Wenger, Roland H., Kvietikova, Ivica, Whitelaw, Murray L., Toftgård, Rune, Tora, Laszlo, Gassmann, Max, Poellinger, Lorenz

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Meningococcal disease in travelers: A problem more than a 100 years old by De Tora, L, Da Silva, L

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The cloned human oestrogen receptor contains a mutation which alters its hormone binding properties by Tora, L., Mullick, A., Metzger, D., Ponglikitmongkol, M., Park, I., Chambon, P.

“…We demonstrate here that the human oestrogen receptor (hER) cDNA clone pOR8 obtained from MCF‐7 cells contains an artefactual point mutation which results in…”
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Widely spaced, directly repeated PuGGTCA elements act as promiscuous enhancers for different classes of nuclear receptors by Kato, Shigeaki, Sasaki, Haruna, Suzawa, Miyuki, Masushige, Shoichi, Tora, Laszlo, Chambon, Pierre, Gronemeyer, Hinrich

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Distinct TFIID complexes mediate the effect of different transcriptional activators by Brou, C., Chaudhary, S., Davidson, I., Lutz, Y., Wu, J., Egly, J.M., Tora, L., Chambon, P.

“…Multiple chromatographically separable complexes containing the TATA binding protein (TBP), which exhibit different functional properties, exist in HeLa cells…”
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The N‐terminal domain of the human TATA‐binding protein plays a role in transcription from TATA‐containing RNA polymerase II and III promoters by Lescure, A., Lutz, Y., Eberhard, D., Jacq, X., Krol, A., Grummt, I., Davidson, I., Chambon, P., Tora, L.

“…In eukaryotes, the TATA box binding protein (TBP) is an integral component of the transcription initiation complexes of all three classes of nuclear RNA…”
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Verbal and Visual Memory Improve After Choline Supplementation in Long-Term Total Parenteral Nutrition: A Pilot Study by Buchman, Alan L., Sohel, Mir, Brown, Meredith, Jenden, Donald J., Ahn, Chul, Roch, Margaret, Brawley, Tora L.

“…Background: Previous investigations have demonstrated that choline deficiency, manifested in low plasma-free choline concentration and hepatic injury, may…”
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H3K9 and H3K14 acetylation co-occur at many gene regulatory elements, while H3K14ac marks a subset of inactive inducible promoters in mouse embryonic stem cells by Karmodiya, Krishanpal, Krebs, Arnaud R, Oulad-Abdelghani, Mustapha, Kimura, Hiroshi, Tora, Laszlo

“…Transcription regulation in pluripotent embryonic stem (ES) cells is a complex process that involves multitude of regulatory layers, one of which is…”
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A unified nomenclature for TATA box binding protein (TBP)-associated factors (TAFs) involved in RNA polymerase II transcription by Tora, Làszlò

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The Putative Cofactor TIF1α Is a Protein Kinase That Is Hyperphosphorylated upon Interaction with Liganded Nuclear Receptors by Fraser, Robert A., Heard, David J., Adam, Sylvie, Lavigne, Anne C., Le Douarin, Bertrand, Tora, Laszlo, Losson, Régine, Rochette-Egly, Cécile, Chambon, Pierre

“…Ligand-induced gene activation by nuclear receptors (NRs) is a complex process requiring dissociation of corepressors and recruitment of coactivators. The…”
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