Search Results - "Topkara, Veli"

The Variety of Cardiovascular Presentations of COVID-19 by Fried, Justin A., Ramasubbu, Kumudha, Bhatt, Reema, Topkara, Veli K., Clerkin, Kevin J., Horn, Evelyn, Rabbani, LeRoy, Brodie, Daniel, Jain, Sneha S., Kirtane, Ajay J., Masoumi, Amirali, Takeda, Koji, Kumaraiah, Deepa, Burkhoff, Daniel, Leon, Martin, Schwartz, Allan, Uriel, Nir, Sayer, Gabriel

Get full text

Reverse Remodeling With Left Ventricular Assist Devices by Burkhoff, Daniel, Topkara, Veli K., Sayer, Gabriel, Uriel, Nir

“…This review provides a comprehensive overview of the past 25+ years of research into the development of left ventricular assist device (LVAD) to improve…”
Get full text

Incidence and Implications of Left Ventricular Distention During Venoarterial Extracorporeal Membrane Oxygenation Support by Truby, Lauren K, Takeda, Koji, Mauro, Christine, Yuzefpolskaya, Melana, Garan, Arthur R, Kirtane, Ajay J, Topkara, Veli, Abrams, Darryl, Brodie, Daniel, Colombo, Paolo C, Naka, Yoshifumi, Takayama, Hiroo

“…Left ventricular distention (LVD) during venoarterial extracorporeal membrane oxygenation (VA-ECMO) support is increasingly recognized but seldom reported in…”
Get full text

Simultaneous heart-kidney transplant compared with heart transplant alone in patients with borderline renal function who are not dialysis dependent by Feng, Iris, Wang, Amy S., Takeda, Koji, Topkara, Veli K.

“…This study assessed characteristics and outcomes of patients who are not dependent on dialysis receiving simultaneous heart kidney transplantation versus heart…”
Get full text

Residual mitral regurgitation in patients with left ventricular assist device support – An INTERMACS analysis by Jain, Rashmi, Truby, Lauren K., Topkara, Veli K.

“…Left ventricular assist device (LVAD) placement frequently leads to a reduction in the severity of functional mitral regurgitation (MR). However, a significant…”
Get full text

Mechanical circulatory support device selection for bridging to cardiac transplantation: a clinical guide by Miller, Tamari, Topkara, Veli K

“…Many patients listed for transplant require temporary or durable mechanical circulatory support (MCS) devices for bridging to cardiac transplantation. The…”
Get more information

Improved outcomes from extracorporeal membrane oxygenation versus ventricular assist device temporary support of primary graft dysfunction in heart transplant by Takeda, Koji, MD, PhD, Li, Boyangzi, PhD, Garan, Arthur R., MD, Topkara, Veli K., MD, Han, Jiho, BS, Colombo, Paolo C., MD, Farr, Maryjane A., MD, Naka, Yoshifumi, MD, PhD, Takayama, Hiroo, MD, PhD

“…Background Primary graft dysfunction (PGD) is one of the most common causes of early mortality after orthotopic heart transplantation. Mechanical circulatory…”
Get full text

Evolving indications and management patterns in heart–kidney transplantation by Lang, Frederick M., Topkara, Veli K.

“…Purpose of review Dual heart – kidney transplantation (HKT) is an increasingly utilized option for patients with end-stage heart failure and impaired renal…”
Get full text

Prognostic Impact of Pulmonary Artery Pulsatility Index (PAPi) in Patients With Advanced Heart Failure: Insights From the ESCAPE Trial by Kochav, Stephanie Meller, Flores, Raul J., Truby, Lauren K., Topkara, Veli K.

“…The pulmonary artery pulsatility index (PAPi), defined as the ratio of pulmonary artery pulse pressure to right atrial pressure, emerged as a powerful…”
Get full text

Deep RNA Sequencing Reveals Dynamic Regulation of Myocardial Noncoding RNAs in Failing Human Heart and Remodeling With Mechanical Circulatory Support by Yang, Kai-Chien, Yamada, Kathryn A, Patel, Akshar Y, Topkara, Veli K, George, Isaac, Cheema, Faisal H, Ewald, Gregory A, Mann, Douglas L, Nerbonne, Jeanne M

“…BACKGROUND—Microarrays have been used extensively to profile transcriptome remodeling in failing human heart, although the genomic coverage provided is limited…”
Get full text

Clinical and hemodynamic effects of intra-aortic balloon pump therapy in chronic heart failure patients with cardiogenic shock by Fried, Justin A., Nair, Abhinav, Takeda, Koji, Clerkin, Kevin, Topkara, Veli K., Masoumi, Amirali, Yuzefpolskaya, Melana, Takayama, Hiroo, Naka, Yoshifumi, Burkhoff, Daniel, Kirtane, Ajay, Karmpaliotis, Dimitrios, Moses, Jeffrey, Colombo, Paolo C., Garan, A. Reshad

“…The role of the intra-aortic balloon pump (IABP) in acute decompensated heart failure (HF) with cardiogenic shock (CS) is largely undefined. In this study we…”
Get full text

Impact of Bridge to Transplantation With Continuous-Flow Left Ventricular Assist Devices on Posttransplantation Mortality: A Propensity-Matched Analysis of the United Network of Organ Sharing Database by Truby, Lauren K, Farr, Maryjane A, Garan, A Reshad, Givens, Raymond, Restaino, Susan W, Latif, Farhana, Takayama, Hiroo, Naka, Yoshifumi, Takeda, Koji, Topkara, Veli K

“…BACKGROUND:Bridge to transplantation (BTT) with left ventricular assist devices (LVADs) is a mainstay of therapy for heart failure in patients awaiting heart…”
Get full text

Machine Learning-Based Prediction of Myocardial Recovery in Patients With Left Ventricular Assist Device Support by Topkara, Veli K., Elias, Pierre, Jain, Rashmi, Sayer, Gabriel, Burkhoff, Daniel, Uriel, Nir

“…Prospective studies demonstrate that aggressive pharmacological therapy combined with pump speed optimization may result in myocardial recovery in larger…”
Get full text

Cardiac recovery via extended cell-free delivery of extracellular vesicles secreted by cardiomyocytes derived from induced pluripotent stem cells by Liu, Bohao, Lee, Benjamin W., Nakanishi, Koki, Villasante, Aranzazu, Williamson, Rebecca, Metz, Jordan, Kim, Jinho, Kanai, Mariko, Bi, Lynn, Brown, Kristy, Di Paolo, Gilbert, Homma, Shunichi, Sims, Peter A., Topkara, Veli K., Vunjak-Novakovic, Gordana

“…The ability of extracellular vesicles (EVs) to regulate a broad range of cellular processes has recently been exploited for the treatment of diseases. For…”
Get full text

Infectious Complications in Patients With Left Ventricular Assist Device: Etiology and Outcomes in the Continuous-Flow Era by Topkara, Veli K., MD, Kondareddy, Sreekanth, MD, Malik, Fardina, MD, Wang, I.-Wen, MD, PhD, Mann, Douglas L., MD, Ewald, Gregory A., MD, Moazami, Nader, MD

“…Background Continuous-flow left ventricular assist devices (LVAD) are increasingly being used in patients with end-stage heart failure and have largely…”
Get full text

Outcomes After Stroke Complicating Left Ventricular Assist Device by Willey, Joshua Z., MD, MS, Gavalas, Michael V., MD, Trinh, Pauline N., MPH, Yuzefpolskaya, Melana, MD, Garan, A. Reshad, MD, Levin, Allison P, Takeda, Koji, MD, PhD, Takayama, Hiroo, MD, PhD, Fried, Justin, MD, Naka, Yoshifumi, MD, PhD, Topkara, Veli K., MD, Colombo, Paolo C., MD

“…Background Stroke is one of the leading complications during continuous flow-left ventricular assist device (CF-LVAD) support. Risk factors have been well…”
Get full text

Aortic Insufficiency During Contemporary Left Ventricular Assist Device Support: Analysis of the INTERMACS Registry by Truby, Lauren K, Garan, A Reshad, Givens, Raymond C, Wayda, Brian, Takeda, Koji, Yuzefpolskaya, Melana, Colombo, Paolo C, Naka, Yoshifumi, Takayama, Hiroo, Topkara, Veli K

“…This study sought to evaluate the impact of moderate to severe aortic insufficiency (AI) on outcomes in patients with continuous flow left ventricular assist…”
Get full text

Gut microbial diversity, inflammation, and oxidative stress are associated with tacrolimus dosing requirements early after heart transplantation by Jennings, Douglas L, Bohn, Bruno, Zuver, Amelia, Onat, Duygu, Gaine, Maureen, Royzman, Eugene, Hupf, Jonathan, Brunjes, Danielle, Latif, Farhana, Restaino, Susan, Garan, Arthur R, Topkara, Veli K, Takayama, Hiroo, Takeda, Koji, Naka, Yoshifumi, Farr, Maryjane, Nandakumar, Renu, Uhlemann, Anne-Catrin, Colombo, Paolo C, Demmer, Ryan T, Yuzefpolskaya, Melana

“…Effective tacrolimus (TAC) dosing is hampered by complex pharmacokinetics and significant patient variability. The gut microbiome, a key mediator of…”
Get full text

Role of MicroRNAs in Cardiac Remodeling and Heart Failure by Topkara, Veli K., Mann, Douglas L.

“…MicroRNAs (miRNAs) are endogenous, short (~22 nucleotide), evolutionarily conserved, non-coding RNAs that regulate gene expression at the post-transcriptional…”
Get full text

Critically appraising the 2018 United Network for Organ Sharing donor allocation policy: adding life boats or rearranging the deck chairs? by Truby, Lauren K., Farr, Maryjane, Topkara, Veli K.

“…Due to the growing mismatch between donor supply and demand as well as unacceptably high transplant waitlist mortality, the heart organ allocation system was…”
Get full text