Search Results - "Topel, Hande"

lncRNA HOTAIR overexpression induced downregulation of c-Met signaling promotes hybrid epithelial/mesenchymal phenotype in hepatocellular carcinoma cells by Topel, Hande, Bagirsakci, Ezgi, Comez, Dehan, Bagci, Gulsun, Cakan-Akdogan, Gulcin, Atabey, Nese

“…Epithelial-to-mesenchymal transition (EMT) and mesenchymal-to-epithelial transition (MET) are both reversible processes, and regulation of phenotypical…”
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High glucose induced c-Met activation promotes aggressive phenotype and regulates expression of glucose metabolism genes in HCC cells by Topel, Hande, Bağırsakçı, Ezgi, Yılmaz, Yeliz, Güneş, Ayşim, Bağcı, Gülsün, Çömez, Dehan, Kahraman, Erkan, Korhan, Peyda, Atabey, Neşe

“…Hepatocellular carcinoma (HCC) is strongly associated with metabolic dysregulations/deregulations and hyperglycemia is a common metabolic disturbance in…”
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A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism by Pradas-Juni, Marta, Hansmeier, Nils R., Link, Jenny C., Schmidt, Elena, Larsen, Bjørk Ditlev, Klemm, Paul, Meola, Nicola, Topel, Hande, Loureiro, Rute, Dhaouadi, Ines, Kiefer, Christoph A., Schwarzer, Robin, Khani, Sajjad, Oliverio, Matteo, Awazawa, Motoharu, Frommolt, Peter, Heeren, Joerg, Scheja, Ludger, Heine, Markus, Dieterich, Christoph, Büning, Hildegard, Yang, Ling, Cao, Haiming, Jesus, Dario F. De, Kulkarni, Rohit N., Zevnik, Branko, Tröder, Simon E., Knippschild, Uwe, Edwards, Peter A., Lee, Richard G., Yamamoto, Masayuki, Ulitsky, Igor, Fernandez-Rebollo, Eduardo, Vallim, Thomas Q. de Aguiar, Kornfeld, Jan-Wilhelm

“…Obesity and type 2 diabetes mellitus are global emergencies and long noncoding RNAs (lncRNAs) are regulatory transcripts with elusive functions in metabolism…”
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Mouse vascularized adipose spheroids: an organotypic model for thermogenic adipocytes by Davidsen, Laura Ingeborg, Hagberg, Carolina E, Goitea, Victor, Lundby, Stine Meinild, Larsen, Steen, Ebbesen, Morten Frendø, Stanic, Natasha, Topel, Hande, Kornfeld, Jan-Wilhelm

“…Adipose tissues, particularly beige and brown adipose tissue, play crucial roles in energy metabolism. Brown adipose tissues' thermogenic capacity and the…”
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Pleiotropic Effects of Heparins: From Clinical Applications to Molecular Mechanisms in Hepatocellular Carcinoma by Atabey, Neşe, Topel, Hande, Güneş, Ayşim, Bağırsakçı, Ezgi, Yılmaz, Yeliz, Korhan, Peyda, Carr, Brian I.

“…Hepatocellular carcinoma (HCC) is a major health problem worldwide and most cases are incurable because of late presentation. It is the most common primary…”
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c-Met activation promotes extravasation of hepatocellular carcinoma cells into 3D-cultured hepatocyte cells in lab-on-a-chip device by Bagci, Gulsun, Comez, Dehan, Topel, Hande, Yilmaz, Yeliz, Bagirsakci, Ezgi, Gunes, Aysim, Batı Ayaz, Gizem, Tahmaz, Ismail, Bilgen, Muge, Solmaz, Gulhas, Pesen Okvur, Devrim, Atabey, Nese

“…Activation of c-Met signaling is associated with an aggressive phenotype and poor prognosis in hepatocellular carcinoma (HCC); however, its contribution to…”
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Genetics and epigenetics of liver cancer by Ozen, Cigdem, Yildiz, Gokhan, Dagcan, Alper Tunga, Cevik, Dilek, Ors, Aysegul, Keles, Umur, Topel, Hande, Ozturk, Mehmet

“…Hepatocellular carcinoma (HCC) represents a major form of primary liver cancer in adults. Chronic infections with hepatitis B (HBV) and C (HCV) viruses and…”
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Heparin treatment increases thioredoxin interacting protein expression in hepatocellular carcinoma cells by Gunes, Aysim, Iscan, Evin, Topel, Hande, Avci, Sanem Tercan, Gumustekin, Mukaddes, Erdal, Esra, Atabey, Nese

“…•Heparin increases TXNIP expression in HCC cells through: ChoRE-b on TXNIP promoter, nuclear accumulation of ChREBP/MondoA-Mlx, regulation of histon…”
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Signaling Pathways as Potential Therapeutic Targets in Hepatocarcinogenesis by Yılmaz, Yeliz, Güneş, Ayşim, Topel, Hande, Atabey, Neşe

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Cold-induced expression of a truncated adenylyl cyclase 3 acts as rheostat to brown fat function by Khani, Sajjad, Topel, Hande, Kardinal, Ronja, Tavanez, Ana Rita, Josephrajan, Ajeetha, Larsen, Bjørk Ditlev Marcher, Gaudry, Michael James, Leyendecker, Philipp, Egedal, Nadia Meincke, Güller, Aylin Seren, Stanic, Natasa, Ruppert, Phillip M. M., Gaziano, Isabella, Hansmeier, Nils Rouven, Schmidt, Elena, Klemm, Paul, Vagliano, Lara-Marie, Stahl, Rainer, Duthie, Fraser, Krause, Jens-Henning, Bici, Ana, Engelhard, Christoph Andreas, Gohlke, Sabrina, Frommolt, Peter, Gnad, Thorsten, Rada-Iglesias, Alvaro, Pradas-Juni, Marta, Schulz, Tim Julius, Wunderlich, Frank Thomas, Pfeifer, Alexander, Bartelt, Alexander, Jastroch, Martin, Wachten, Dagmar, Kornfeld, Jan-Wilhelm

“…Promoting brown adipose tissue (BAT) activity innovatively targets obesity and metabolic disease. While thermogenic activation of BAT is well understood, the…”
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Hepatosellüler Karsinomda Epitelial-Mezenkimal Transizyon Sürecinde C-Met Sinyalizasyonu ve Lncrna Hotair'ın Ilişkisinin Araştırılması by Topel, Hande

“…Amaç:Bu çalışmada hepatosellüler karsiomda (HCC) epitelial-mezenkimal transizyon (EMT) sürecinde c-Met tirozin kinaz reseptörü ile lncRNA HOTAIR’in olası…”
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Neuronal apoptosis in the neonates born to preeclamptic mothers by Cosar, Hese, Ozer, Erdener, Topel, Hande, Kahramaner, Zelal, Turkoglu, Ebru, Erdemir, Aydin, Sutcuoglu, Sumer, Bagriyanik, Alper, Ozer, Esra Arun

“…Abstract Objective: Preeclampsia may result in uteroplacental insufficiency and chronic intrauterine fetal distress. The aim of this study is to address this…”
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Kemoterapiye Maruz Kalmış Dişi Sıçanlarda Rosiglitazone'un Ovaryuma Etkisi by Topel, Hande

“…Amaç:Çalışmamızda kemoterapötik bir etken madde olan ve ovaryum üzerindeki etkileri geri dönüşümsüz olan siklofosfamidin yarattığı ovarial hasarda; PPARG…”
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