Search Results - "Topçu,Atilla"

Bee pollen increases hippocampal brain-derived neurotrophic factor and suppresses neuroinflammation in adult rats with chronic immobilization stress by Saral, Özlem, Şahin, Hüseyin, Saral, Sinan, Alkanat, Mehmet, Akyıldız, Kerimali, Topçu, Atilla, Yılmaz, Adnan

“…•Immobilization stress affects hippocampal inflammation and the antioxidant system.•Immobilization stress reduces hippocampal brain-derived neurotrophic factor…”
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Apelin-13 activates the hippocampal BDNF/TrkB signaling pathway and suppresses neuroinflammation in male rats with cisplatin-induced cognitive dysfunction by Saral, Sinan, Topçu, Atilla, Alkanat, Mehmet, Mercantepe, Tolga, Akyıldız, Kerimali, Yıldız, Lamiye, Tümkaya, Levent, Yazıcı, Zihni Açar, Yılmaz, Adnan

“…It has been established that cisplatin causes neuronal damage and cognitive impairment. However, the mechanism is not sufficiently clear. Apelin-13 is an…”
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Agomelatine attenuates cisplatin-induced cognitive impairment via modulation of BDNF/TrkB signaling in rat hippocampus by Saral, Sinan, Topçu, Atilla, Alkanat, Mehmet, Mercantepe, Tolga, Şahin, Zafer, Akyıldız, Kerimali, Karataş, Kader Semra, Yıldız, Lamiye, Tümkaya, Levent, Yazıcı, Zihni Açar

“…Cisplatin is a drug used effectively in the treatment of malignant tumors. However, cisplatin has many side effects, including cognitive impairment…”
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Can Dexmedetomidine Be Effective in the Protection of Radiotherapy-Induced Brain Damage in the Rat? by Çınar, Seda, Tümkaya, Levent, Mercantepe, Tolga, Saral, Sinan, Rakıcı, Sema, Yılmaz, Adnan, Topçu, Atilla, Şen, Ahmet, Karakaş, Sibel

“…Approximately 7 million people are reported to be undergoing radiotherapy (RT) at any one time in the world. However, it is still not possible to prevent…”
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Towards a comprehensive tobacco-cessation approach: A pilot-training using simulation based-learning among medical students in Türkiye by Karadoğan, Dilek, Ardıç, Cüneyt, Telatar, Tahsin Gökhan, Kanbay, Yalçın, Kayaalp, Ekrem, Dedecan, Muhammet Ali, Puşuroğlu, Meltem, Özyurt, Songül, Özçelik, Neslihan, Yılmaz Kara, Bilge, Emlek, Nadir, Topçu, Atilla, Saral, Sinan, Uzun, Kerem, Konyalıhatipoğlu, Esin Bilgin, Karahacıoğlu Madran, Elvin, Kavak, İsmail, Göksun, Hasan, Şahin, Ünal, Belo Ravara, Sofia

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Dose Dependent Effects of Lithium Carbonate on Rat Thyroid Hormones, Parathormon and Calcium Levels with Thyroid Tissue by Topçu, Atilla

“…Objective: The aim of this research was to investigate the effects of subacute use of lithium carbonate (Li2CO3), on serum T3, T4, thyroid stimulating hormone…”
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Positive effects of white tea on breast cancer: N-methyl-N-nitrozourea intraductal induced breast carcinoma model by Mataraci Karakas, Sibel, Yilmaz, Adnan, Mercantepe, Tolga, Topcu, Atilla, Pinarbas, Esra

“…•Induction of intraductal breast carcinoma by N-methyl-N-nitrozourea (MNU).•White tea exhibits chemopreventive effect in breast cancer.•White tea prevents DNA…”
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Protective effects of nebivolol on ovarian ischemia–reperfusion injury in rat by Colak, Sabri, Gurlek, Beril, Topcu, Atilla, Tumkaya, Levent, Mercantepe, Tolga, Yilmaz, Adnan

“…Aim Ovarian torsion is a common gynecological emergency of reproductive ages, occurring at rates of 2.7–7.4%. This study aimed to evaluate the antioxidant…”
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The Nephroprotective Effect of Punica granatum Peel Extract on LPS-Induced Acute Kidney Injury by Sahin Aktura, Sena, Sahin, Kazim, Tumkaya, Levent, Mercantepe, Tolga, Topcu, Atilla, Pinarbas, Esra, Yazici, Zihni Acar

“…Sepsis is an exaggerated immune response resulting from systemic inflammation, which can damage tissues and organs. Acute kidney injury has been detected in at…”
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Protective effects of amifostine, curcumin, and melatonin against cisplatin-induced acute kidney injury by Mercantepe, Filiz, Mercantepe, Tolga, Topcu, Atilla, Yılmaz, Adnan, Tumkaya, Levent

“…Despite the enormous advances made in the field of oncology, no solution to the side effect of nephrotoxicity caused by cisplatin used as an antineoplastic…”
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The effects of N-acetylcysteine on radiotherapy-induced small intestinal damage in rats by Mercantepe, Filiz, Topcu, Atilla, Rakici, Sema, Tumkaya, Levent, Yilmaz, Adnan

“…Six million cancer patients worldwide receive radiotherapy, either alone or in combination with other cancer treatments annually. The purpose of this study was…”
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The protective effects of angiotensin-converting enzyme inhibitor against cecal ligation and puncture-induced sepsis via oxidative stress and inflammation by Kostakoglu, Ugur, Topcu, Atilla, Atak, Mehtap, Tumkaya, Levent, Mercantepe, Tolga, Uydu, Huseyin Avni

“…Sepsis is a severe public health problem affecting millions of individuals, with global mortality rates caused by lower respiratory tract infections are…”
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An investigation of the effects of metformin on ovarian ischemia-reperfusion injury in rats by Topcu, Atilla, Balik, Gulsah, Atak, Mehtap, Mercantepe, Tolga, Uydu, Huseyin Avni, Tumkaya, Levent

“…Damage to the ovaries or tissue torsion can significantly reduce the ovarian reserve and thus cause severe gynecological and hormonal deficiencies. The…”
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Agomelatine on cisplatin-induced nephrotoxicity via oxidative stress and apoptosis by Dil, Eyup, Topcu, Atilla, Mercantepe, Tolga, Tumkaya, Levent, Akyildiz, Kerimali, Saral, Sinan, Yilmaz, Adnan

“…Drug-induced nephrotoxicity is the greatest deterrent to the use of cisplatin, which is a frequently used chemotherapeutic with proven effectiveness in cancer…”
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The effect of the calcium channel blocker nimodipine on hippocampal BDNF/Ach levels in rats with experimental cognitive impairment by Topcu, Atilla, Saral, Sinan, Ozturk, Aykut, Saral, Ozlem, Kaya, Ali Koray

“…Alzheimer's disease (AD) occurs in approximately 10% to 30% of individuals aged 65 or older worldwide. Novel therapeutic agents therefore need to be discovered…”
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The protective role of fosfomycin in lung injury due to oxidative stress and inflammation caused by sepsis by Yildiz, Ilknur Esen, Topcu, Atilla, Bahceci, Ilkay, Arpa, Medeni, Tumkaya, Levent, Mercantepe, Tolga, Batcik, Sule, Yildiz, Yasin

“…Early and prompt treatment of sepsis by effective antibiotics against susceptible organisms may be lifesaving. However, increased antibiotic resistance and…”
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The effects of vitamin B12 on the TLR-4/NF-κB signaling pathway in ovarian ischemia-reperfusion injury-related inflammation by Deniz, Esra, Topcu, Atilla, Ozturk, Aykut, Ozturk, Seda Duman, Arpa, Medeni, Atak, Mehtap

“…[Display omitted] •Vitamin B12 reduced ovarian damage caused by ischemia/reperfusion.•Vitamin B12 decreased oxidative stress/inflammation damage by TLR-4/NF-κB…”
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An investigation of the effects of N-acetylcysteine on radiotherapy-induced testicular injury in rats by Topcu, Atilla, Mercantepe, Filiz, Rakici, Sema, Tumkaya, Levent, Uydu, Huseyin Avni, Mercantepe, Tolga

“…According to data issued by the International Agency for Research on Cancer in 2012, the estimated number of new cases of all types of cancer worldwide was…”
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The effects of boron nitride/hydroxyapatite compounds on bone defects in osteoporotic rats by Topcu, Atilla, Halici, Zekai, Cadirci, Elif, Karakus, Emre, Dogan, Aysegul, Bakan, Feray, Goncu, Yapıncak, Ay, Nuran, Sahin, Fikrettin

“…•Osteoporotic defect will reach 316 million by 2040.•Osteoporotic model is frequently used in studies on the subject.•BN/HA compound may represent a potent…”
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Long-term protective effects of lamotrigine in a rat ovarian ischemia-reperfusion model by Aktepe, Riza, Ucuncu, Yilmaz, Tumkaya, Levent, Mercantepe, Tolga, Topcu, Atilla, Uydu, Huseyin Avni, Atak, Mehtap

“…Ovarium torsion is a gynecological emergency that is common in women of reproductive age and requires early diagnosis and intervention. In this study, we aimed…”
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