Search Results - "Toosy, A T"

Structural cortical network reorganization associated with early conversion to multiple sclerosis by Tur, C., Eshaghi, A., Altmann, D. R., Jenkins, T. M., Prados, F., Grussu, F., Charalambous, T., Schmidt, A., Ourselin, S., Clayden, J. D., Wheeler-Kingshott, C. A. M. G., Thompson, A. J., Ciccarelli, O., Toosy, A. T.

“…Brain structural covariance networks (SCNs) based on pairwise statistical associations of cortical thickness data across brain areas reflect underlying…”
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Diffusion tensor imaging detects corticospinal tract involvement at multiple levels in amyotrophic lateral sclerosis by Toosy, A T, Werring, D J, Orrell, R W, Howard, R S, King, M D, Barker, G J, Miller, D H, Thompson, A J

“…Background: Histopathological studies of amyotrophic lateral sclerosis (ALS) are of end stage disease. Diffusion tensor imaging (DTI) provides the opportunity…”
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Identifying brain regions for integrative sensorimotor processing with ankle movements by CICCARELLI, O, TOOSY, A. T, MARSDEN, J. F, WHEELER-KINGSHOTT, C. M, SAHYOUN, C, MATTHEWS, P. M, MILLER, D. H, THOMPSON, A. J

“…The objective of this study was to define cortical and subcortical structures activated during both active and passive movements of the ankle, which have a…”
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Abnormalities of cerebral perfusion in multiple sclerosis by Rashid, W, Parkes, L M, Ingle, G T, Chard, D T, Toosy, A T, Altmann, D R, Symms, M R, Tofts, P S, Thompson, A J, Miller, D H

“…Background: Measuring perfusion provides a potential indication of metabolic activity in brain tissue. Studies in multiple sclerosis (MS) have identified areas…”
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Early pericalcarine atrophy in acute optic neuritis is associated with conversion to multiple sclerosis by Jenkins, T M, Ciccarelli, O, Atzori, M, Wheeler-Kingshott, C A M, Miller, D H, Thompson, A J, Toosy, A T

“…BackgroundPrevious work showed that pericalcarine cortical volume loss is evident early after presentation with acute clinically isolated optic neuritis (ON)…”
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Serial magnetization transfer imaging in acute optic neuritis by Hickman, S. J., Toosy, A. T., Jones, S. J., Altmann, D. R., Miszkiel, K. A., MacManus, D. G., Barker, G. J., Plant, G. T., Thompson, A. J., Miller, D. H.

“…In serial studies of multiple sclerosis lesions, reductions in magnetization transfer ratio (MTR) are thought to be due to demyelination and axonal loss, with…”
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From diffusion tractography to quantitative white matter tract measures: a reproducibility study by Ciccarelli, O., Parker, G.J.M., Toosy, A.T., Wheeler-Kingshott, C.A.M., Barker, G.J., Boulby, P.A., Miller, D.H., Thompson, A.J.

“…The aim of this study is to propose methods for assessing the reproducibility of diffusion tractography algorithms in future clinical studies and to show their…”
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Diffusion tensor imaging can detect and quantify corticospinal tract degeneration after stroke by Werring, David J, Toosy, Ahmed T, Clark, Christopher A, Parker, Geoffrey JM, Barker, Gareth J, Miller, David H, Thompson, Alan J

“…Diffusion tensor imaging (DTI) fully characterises water molecule mobility in vivo, allowing an exploration of fibre tract integrity and orientation in the…”
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Diffusion tractography based group mapping of major white-matter pathways in the human brain by Ciccarelli, O, Toosy, A.T, Parker, G.J.M, Wheeler-Kingshott, C.A.M, Barker, G.J, Miller, D.H, Thompson, A.J

“…Tractography uses diffusion tensor imaging data to trace white matter pathways in vivo within the brain. We have constructed group maps that represent three…”
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Functional magnetic resonance imaging of the cortical response to photic stimulation in humans following optic neuritis recovery by Toosy, A.T, Werring, D.J, Bullmore, E.T, Plant, G.T, Barker, G.J, Miller, D.H, Thompson, A.J

“…Recovery from optic neuritis has been shown to be associated with an abnormal functional MRI (fMRI) response following exposure of the eye to an epoch based…”
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Recovery from optic neuritis is associated with a change in the distribution of cerebral response to visual stimulation: a functional magnetic resonance imaging study by Werring, David J, Bullmore, Edward T, Toosy, Ahmed T, Miller, David H, Barker, Gareth J, MacManus, David G, Brammer, Michael J, Giampietro, Vincent P, Brusa, Adriana, Brex, Peter A, Moseley, Ivan F, Plant, Gordon T, McDonald, W Ian, Thompson, Alan J

“…OBJECTIVES Recovery to normal or near normal visual acuity is usual after acute demyelinating optic neuritis, despite the frequent persistence of conduction…”
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Asymmetrical Activation of Human Visual Cortex Demonstrated by Functional MRI with Monocular Stimulation by Toosy, A.T., Werring, D.J., Plant, G.T., Bullmore, E.T., Miller, D.H., Thompson, A.J.

“…We have demonstrated asymmetric activation patterns in the visual cortices of normal humans who have undergone functional MRI with monocular photic…”
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Functional imaging correlates of fronto-temporal dysfunction in Morvan’s syndrome by Toosy, A T, Burbridge, S E, Pitkanen, M, Loyal, A S, Akanuma, N, Laing, H, Kopelman, M D, Andrews, T C

“…The following blood tests were abnormal: serum sodium 128-132 mmol/l (normal levels, 135-145 mmol/l), creatine phosphokinase 393 IU/l (0-250 IU/l), thyroid…”
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Parinaud's syndrome – A rare presentation of clinically isolated syndrome by Gnanapavan, S, Sillery, E, Acheson, J.F, Toosy, A.T

“…Abstract We present a 26 year old Pakistani lady with first presentation of a demyelinating event, presenting as Parinaud's syndrome. The video demonstrates a…”
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Functional response to active and passive ankle movements with clinical correlations in patients with primary progressive multiple sclerosis by CICCARELLI, Olga, TOOSY, Ahmed T, MARSDEN, Jonathan F, WHEELER-KINGSHOTT, Claudia M, MILLER, David H, MATTHEWS, Paul M, THOMPSON, Alan J

“…Patients with multiple sclerosis (MS) activate a more diffuse cortical network than do healthy subjects when they perform motor tasks. This brain functional…”
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The 412 retrotransposon and the development of gonadal mesoderm in Drosophila by BROOKMAN, J. J, TOOSY, A. T, SHASHIDHARA, L. S, WHITE, R. A. H

“…We have shown that the expression of the 412 retrotransposon provides a useful early marker for the development of the gonadal mesoderm in Drosophila embryos…”
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Visual recovery following acute optic neuritis: A clinical, electrophysiological and magnetic resonance imaging study by HICKMAN, Simon J, TOOSY, Ahmed T, MISZKIEL, Katherine A, JONES, Stephen J, ALTMANN, Daniel R, MACMANUS, David G, PLANT, Gordon T, THOMPSON, Alan J, MILLER, David H

“…This study reports the prospective follow-up of a cohort of patients with acute optic neuritis examined with serial visual tests, visual evoked potentials…”
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Monocular complex visual hallucinations and their suppression by eye closure by Toosy, A T, Roberton, B J, Jayaram, H, Plant, G T

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Characterizing function–structure relationships in the human visual system with functional MRI and diffusion tensor imaging by Toosy, Ahmed T, Ciccarelli, Olga, Parker, Geoff J.M, Wheeler-Kingshott, Claudia A.M, Miller, David H, Thompson, Alan J

“…A key objective in neuroscience is to improve our understanding of the relationship between brain function and structure. We investigated this in the posterior…”
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Optic radiation changes after optic neuritis detected by tractography-based group mapping by Ciccarelli, Olga, Toosy, Ahmed T., Hickman, Simon J., Parker, Geoff J.M., Wheeler-Kingshott, Claudia A.M., Miller, David H., Thompson, Alan J.

“…Postmortem data suggest that trans‐synaptic degeneration occurs in the lateral geniculate nucleus after optic nerve injury. This study investigated in vivo the…”
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