Search Results - "Toomes, Heikki"

Video-Assisted Mediastinoscopic Surgery: Clinical Feasibility and Accuracy of Mediastinal Lymph Node Staging by Witte, Biruta, Wolf, Michael, Huertgen, Martin, Toomes, Heikki

“…This study was conducted to assess indications, procedures, complications, and clinical feasibility of video-assisted mediastinoscopic surgery (VAMS). It also…”
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Who Gains Most? A 10-Year Experience With 611 Thoracoscopic Talc Pleurodeses by Steger, Volker, MD, Mika, Ute, Toomes, Heikki, MD, Walker, Tobias, MD, Engel, Corinna, Kyriss, Thomas, MD, Ziemer, Gerhard, MD, Friedel, Godehard, MD

“…Background Thoracoscopic talc pleurodesis is a therapeutic option for recurrent pleural effusion. Methods This retrospective study included 611 patients who…”
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Results of lung metastasectomy from breast cancer: prognostic criteria on the basis of 467 cases of the international registry of lung metastases by Friedel, Godehard, Pastorino, Ugo, Ginsberg, Robert J., Goldstraw, Peter, Johnston, Micheal, Pass, Harvey, Putnam, Joe B., Toomes, Heikki

“…Objective: Metastatic breast cancer is still defined as an incurable disease. Although the prognosis after resection of isolated metastases to the lung is much…”
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Radical video-assisted mediastinoscopic lymphadenectomy (VAMLA) – technique and first results by Hürtgen, Martin, Friedel, Godehard, Toomes, Heikki, Fritz, Peter

“…Exact pretherapeutic lymph node staging of lung cancer is of special importance for selecting patients for neoadjuvant therapy or for video-assisted…”
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The coin lesion of the lung. A review of 955 resected coin lesions by Toomes, H, Delphendahl, A, Manke, H G, Vogt-Moykopf, I

“…The retrospective study of 955 coin lesions of the lung showed 49% to be malignant. The proportion of malignant lesions increased with age. In patients older…”
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Prognosis in N2 NSCLC by Friedel, Godehard, Steger, Volker, Kyriss, Thomas, Zoller, Jutta, Toomes, Heikki

“…The prognosis of bronchogenic carcinoma in stage III N2 is poor. Five-year survival ranges between 0 and 5%. Lymph-node involvement itself still is the main…”
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General thoracic surgery as a monospeciality — a realistic vision? by Toomes, Heikki

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Treatment of lung cancer in the elderly. Part I: non-small cell lung cancer by Weinmann, Martin, Jeremic, Branislav, Toomes, Heikki, Friedel, Godehard, Bamberg, Michael

“…There is a general trend worldwide of an increasing incidence of elderly population. Age is the greatest risk factor for cancer; therefore, this demographic…”
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The development of General Thoracic Surgery by Toomes, Heikki, Swoboda, Lothar

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Dose optimization of a doxorubicin prodrug (HMR 1826) in isolated perfused human lungs: low tumor pH promotes prodrug activation by beta-glucuronidase by Mürdter, Thomas E, Friedel, Godehard, Backman, Janne T, McClellan, Monika, Schick, Monika, Gerken, Manfred, Bosslet, Klaus, Fritz, Peter, Toomes, Heikki, Kroemer, Heyo K, Sperker, Bernhard

“…HMR 1826 (N-[4-beta-Glucuronyl-3-nitrobenzyl-oxycarbonyl]doxorubicin) is a nontoxic glucuronide prodrug from which active doxorubicin is released by…”
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Resection of pulmonary metastases from renal cell carcinoma by Friedel, G, Hürtgen, M, Penzenstadler, M, Kyriss, T, Toomes, H

“…Between 1980 and 1995, 77 patients underwent complete resection of pulmonary metastases from a renal cell carcinoma after exclusion of a primary tumor…”
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Enhanced uptake of doxorubicin into bronchial carcinoma : β-glucuronidase mediates release of doxorubicin from a glucuronide prodrug (HMR 1826) at the tumor site by MÜRDTER, T. E, SPERKER, B, KROEMER, H. K, KIVISTÖ, K. T, MCCLELLAN, M, FRITZ, P, FRIEDEL, G, LINDER, A, BOSSLET, K, TOOMES, H, DIERKESMANN, R

“…Lack of tumor selectivity is a severe limitation of cancer chemotherapy. Consequently, reducing dose-limiting organ toxicities such as the cardiac toxicity of…”
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Systematic Video-Assisted Mediastinoscopic Lymphadenectomy (VAMLA) by Hürtgen, Martin, Friedel, Godehard, Witte, Biruta, Toomes, Heikki, Fritz, Peter

“…Accurate mediastinal lymph node dissection during thoracotomy is mandatory for staging and for adjuvant therapy in lung cancer. Pre-therapeutic staging for…”
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Long-term results after 110 tracheal resections by Friedel, Godehard, Kyriss, Thomas, Leitenberger, Andrea, Toomes, Heikki

“…Among the many therapeutic options for treating tracheal stenosis (e.g. bouginage, laser resection and stenting), segmental resection and reconstruction with…”
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Carcinoid lung tumors: long-term results from 111 resections by Kyriss, Thomas, Maier, Sibylle, Veit, Stefanie, Fritz, Peter, Toomes, Heikki, Friedel, Godehard

“…Carcinoids are rare neuroendocrine tumors of the bronchial system. Only recently, the histological classification was standardized, and there are varying…”
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Neoadjuvant chemoradiotherapy of stage III non-small-cell lung cancer by Friedel, Godehard, Hruska, Dagmar, Budach, Wilfried, Wolf, Martin, Kyriss, Thomas, Hürtgen, Martin, Eulenbruch, Hans-Paul, Dierkesmann, Rainer, Toomes, Heikki

“…Twenty to 30% of patients with non-small-cell lung cancer (NSCLC) in stage III are not resectable primarily with 5-year survival less than 10%. Since the…”
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Full-thickness chest wall resection for locally recurrent breast cancer by Friedel, Godehard, Kuipers, Thomas, Engel, Corinna, Schopf, Christine, Veit, Stefanie, Zoller, Jutta, Kyriss, Thomas, Greulich, Michael, Toomes, Heikki

“…In spite of available recommendations, therapeutic procedures of locally recurrent breast cancer are very different. In a retrospective study, the…”
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Variability of cyclophosphamide uptake into human bronchial carcinoma : consequences for local bioactivation by BOHNENSTENGEL, F, FRIEDEL, G, RITTER, C. A, MCCLELLAN, M, FRITZ, P, EICHELBAUM, M, LINDER, A, TOOMES, H, DIERKESMANN, R, KROEMER, H. K

“…The alkylating cytostatic prodrug cyclophosphamide is bioactivated by the human cytochrome P450 enzyme system. Since these enzymes are not only expressed in…”
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Ligands for Viscum album agglutinin and galectin-1 in human lung cancer: Is there any prognostic relevance? by Fritz, Peter, Seizer-Schmidt, Regine, Mürdter, Thomas E., Kroemer, Heyo K., Aulitzky, Walter, André, Sabine, Hans-Gabius, Joachim, Friedel, Godehard, Toomes, Heikki, Siegle, Isabel

“…Viscum album agglutinin (VAA) is an extract component of mistletoe. It belongs to the plant lectin family and exerts various biological effects such as…”
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Different growth rates of lung tumours in man and their xenografts in nude mice by Mattern, J, Wayss, K, Haag, D, Toomes, H, Volm, M

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