Search Results - "Tonussi, Carlos Rogério"

Antinociceptive and anti-inflammatory activities of the Jatropha isabellei dichloromethane fraction and isolation and quantitative determination of jatrophone by UFLC-DAD by Fröhlich, Janaina Kieling, Stein, Taciane, da Silva, Layzon Antônio, Biavatti, Maique Weber, Tonussi, Carlos Rogério, Lemos-Senna, Elenara

“…Context: Jatropha isabellei Müll. Arg. (Euphorbiaceae) has been used in the traditional medicine to treat arthritis. Objective: To evaluate the…”
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Detection of blood flow perfusion and post - occlusive reactive hyperemia in the skeletal muscle of rats by Souza-Silva, Eduardo, Ascenso, Ruy, Tonussi, Carlos Rogério, da Silva-Santos, José Eduardo

“…Post-occlusive reactive hyperemia (PORH) remains poorly understood in the skeletal muscle system. This study was designed to validate an alternative strategy…”
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Intra-articular injection of 2-pyridylethylamine produces spinal NPY-mediated antinociception in the formalin-induced rat knee-joint pain model by Souza-Silva, Eduardo, Stein, Taciane, Mascarin, Lucas Zanon, Dornelles, Fabiana Noronha, Bicca, Maíra Assunção, Tonussi, Carlos Rogério

“…•The antinociceptive effect of 2-PEA (H1R-agonist) is due to activation of histamine-sensitive deep articular afferent fiber.•Intrathecal Y1R antagonist…”
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Histaminergic Pharmacology Modulates the Analgesic and Antiedematogenic Effects of Spinally Injected Morphine by Stein, Taciane, Souza-Silva, Eduardo, Mascarin, Lucas, Eto, Carolina, Fin, Franci Ellen, Tonussi, Carlos Rogério

“…Histamine receptors are known to participate in spinal cord nociceptive transmission, and previous studies have suggested that histaminergic receptors are…”
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Analgesic and anti-edematogenic effects of oral trypsin were abolished after subdiaphragmatic vagotomy and spinal monoaminergic inhibition in rats by Lucena, Flora, Foletto, Vanessa, Mascarin, Lucas Zanon, Tonussi, Carlos Rogério

“…Rheumatoid arthritis brings great burdens to the patients. In addition to the highly expensive treatment, they are commonly associated with severe side…”
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Development and in vivo evaluation of lipid-based nanocarriers containing Jatropha isabellei dry extract from the dichloromethane fraction intended for oral treatment of arthritic diseases by Fröhlich, Janaina Kieling, Meyer, Priscila Aguiar, Stein, Taciane, Tonussi, Carlos Rogério, Lemos-Senna, Elenara

“…Abstract In this study, a dichloromethane fraction dry extract from the underground parts of Jatropha isabellei (DFJi) was used to prepare lipid nanocarriers…”
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Evidence that LPS-reactive arthritis in rats depends on the glial activity and the fractalkine–TNF-α signaling in the spinal cord by Bressan, Elisângela, Peres, Kaite Cristiane, Tonussi, Carlos Rogério

“…It is known that primary afferent central terminal sensitization can influence peripheral inflammation, however, it remains to be understood whether spinal…”
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LPS-induced knee-joint reactive arthritis and spinal cord glial activation were reduced after intrathecal thalidomide injection in rats by Bressan, Elisângela, Mitkovski, Mišo, Tonussi, Carlos Rogério

“…Thalidomide is thought to prevent TNF-α production, and such mechanism could be useful in a spinally delivered drug approach for the control of peripheral…”
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Histamine produces opposing effects to serotonin in the knee joint of rats by Souza-Silva, Eduardo, de Oliveira, Daniel Teixeira, Eto, Carolina, Stein, Taciane, Tonussi, Carlos Rogério

“…Formalin injected in the knee joint of rats produces concentration-dependent nociception, edema, and plasma leakage (PL). Herein, we investigated the effect of…”
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Intrathecally Injected Morphine Inhibits Inflammatory Paw Edema: The Involvement of Nitric Oxide and Cyclic-Guanosine Monophosphate by Brock, Sara Comelli, Tonussi, Carlos Rogério

“…Morphine can inhibit inflammatory edema in experimental animals. The mechanisms and sites by which opioids exert this effect are still under debate. Since the…”
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Standardization of an experimental model suitable for studies on the effect of exercise on arthritis by Gomes, Raquel Pinheiro, Bressan, Elisangela, Silva, Tatiane Morgana da, Gevaerd, Monique da Silva, Tonussi, Carlos Rogério, Domenech, Susana Cristina

“…To standardize an experimental model of chronic monoarthritis induced by complete Freund's adjuvant appropriate for the analysis of the effect of walking on…”
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Contribution of TNFα, IL-1β and CINC-1 for articular incapacitation, edema and cell migration in a model of LPS-induced reactive arthritis by Bressan, Elisângela, De Queiroz Cunha, Fernando, Tonussi, Carlos Rogério

“…The protective effect of anti-CINC-1, -TNFα and -IL-1β antisera on articular inflammatory incapacitation, articular diameter and synovial fluid cell content,…”
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Evaluation of the pro-inflammatory potential of nanostructured drug carriers in knee-joints of rats: effect on nociception, edema, and cell migration by de Faria, Tatiany Jovita, Souza-Silva, Eduardo, de Oliveira, Daniel Teixeira, Senna, Elenara Lemos, Tonussi, Carlos Rogério

“…Nanocarriers have been developed aiming at drug delivery; however, the irritating effects of these nanoparticles on naïve or inflamed articular tissues are not…”
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Articular nociception induced by endothelin-1, carrageenan and LPS in naive and previously inflamed knee-joints in the rat: inhibition by endothelin receptor antagonists by De-Melo, Josélia Daher, Tonussi, Carlos Rogério, D'Orléans-Juste, Pedro, Rae, Giles Alexander

“…Endothelin-1, unlike the selective endothelin ETB receptor agonist sarafotoxin S6c, causes nociception in the rat when injected intraarticularly into the naive…”
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Padronização de modelo experimental adequado a estudos do efeito do exercício na artrite by Gomes, Raquel Pinheiro, Bressan, Elisangela, Silva, Tatiane Morgana da, Gevaerd, Monique da Silva, Tonussi, Carlos Rogério, Domenech, Susana Cristina

“…OBJETIVO: Padronizar um modelo experimental de monoartrite crônica induzida por adjuvante completo de Freund apropriado à análise do efeito da deambulação na…”
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Effects of one minute and ten minutes of walking activity in rats with arthritis induced by complete Freund's adjuvant on pain and edema symptoms by Gomes, Raquel Pinheiro, Bressan, Elisângela, Silva, Tatiane Morgana da, Gevaerd, Monique da Silva, Tonussi, Carlos Rogério, Domenech, Susana Cristina

“…This study evaluated the effects of two protocols of exercise on nociception, edema and cell migration in rats with CFA-induced arthritis. Female Wistar rats…”
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A spinal mechanism for the peripheral anti-inflammatory action of indomethacin by Daher, Josélia Borba, Tonussi, Carlos Rogério

“…In the present study, we evaluated the consequences of prostaglandin E 2 (PGE 2) or indomethacin injection into the spinal cord, on a model of peripheral…”
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Efeitos de um minuto e dez minutos de deambulação em ratos com artrite induzida por adjuvante completo de Freund sobre os sintomas de dor e edema by Gomes, Raquel Pinheiro, Bressan, Elisângela, Silva, Tatiane Morgana da, Gevaerd, Monique da Silva, Tonussi, Carlos Rogério, Domenech, Susana Cristina

“…Este estudo avaliou o efeito de dois protocolos de exercício na nocicepção, edema e migração celular em ratos com artrite induzida por CFA. Ratos Wistar fêmeas…”
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Evidências de que um protocolo de atividade física pode reduzir a contagem de leucócitos sinoviais de ratos artríticos by Gomes, Raquel Pinheiro, Bressan, Elisângela, Silva, Tatiane Morgana da, Domenech, Susana Cristina, Tonussi, Carlos Rogério

“…INTRODUÇÃO: O exercício físico apresenta potenciais benefícios na artrite, retardando a incapacidade funcional e melhorando a função das articulações. Estudos…”
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Contribution of TNFalpha, IL-1beta and CINC-1 for articular incapacitation, edema and cell migration in a model of LPS-induced reactive arthritis by Bressan, Elisângela, Cunha, Fernando De Queiroz, Tonussi, Carlos Rogério

“…The protective effect of anti-CINC-1, -TNFalpha and -IL-1beta antisera on articular inflammatory incapacitation, articular diameter and synovial fluid cell…”
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