Search Results - "Tonn, J"

High-grade glioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up by Stupp, R, Brada, M, van den Bent, M J, Tonn, J-C, Pentheroudakis, G

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High-grade malignant glioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up by Stupp, R., Tonn, J.-C., Brada, M., Pentheroudakis, G.

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Perifocal Edema in Patients with Meningioma is Associated with Impaired Whole-Brain Connectivity as Detected by Resting-State fMRI by Stoecklein, V M, Wunderlich, S, Papazov, B, Thon, N, Schmutzer, M, Schinner, R, Zimmermann, H, Liebig, T, Ricke, J, Liu, H, Tonn, J-C, Schichor, C, Stoecklein, S

“…Meningiomas are intracranial tumors that usually carry a benign prognosis. Some meningiomas cause perifocal edema. Resting-state fMRI can be used to assess…”
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Gross total but not incomplete resection of glioblastoma prolongs survival in the era of radiochemotherapy by KRETH, F. -W, THON, N, TONN, J. -C, SIMON, M, WESTPHAL, M, SCHACKERT, G, NIKKHAH, G, HENTSCHEL, B, REIFENBERGER, G, PIETSCH, T, WELLER, M

“…This prospective multicenter study assessed the prognostic influence of the extent of resection when compared with biopsy only in a contemporary patient…”
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Association of pre-radiotherapy tumour burden and overall survival in newly diagnosed glioblastoma adjusted for MGMT promoter methylation status by Alafandi, A., van Garderen, K.A., Klein, S., van der Voort, S.R., Rizopoulos, D., Nabors, L., Stupp, R., Weller, M., Gorlia, T., Tonn, J.-C., Smits, M.

“…We retrospectively evaluated the association between postoperative pre-radiotherapy tumour burden and overall survival (OS) adjusted for the prognostic value…”
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Case report of a cervical myelomalacia caused by a thoracolumbar intradural disc herniation leading to intracranial hypotension by Ueberschaer, M., Patzig, M., Mueller, K., Schwarting, J., Trabold, R., Tonn, J.-C.

“…A 50-year-old patient was admitted with symptoms of intracranial hypotension. MRI revealed a cervical myelomalacia caused by engorged epidural veins leading to…”
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Leptomeningeal metastasis from solid tumours: EANO–ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up by Le Rhun, E., Weller, M., van den Bent, M., Brandsma, D., Furtner, J., Rudà, R., Schadendorf, D., Seoane, J., Tonn, J.-C., Wesseling, P., Wick, W., Minniti, G., Peters, S., Curigliano, G., Preusser, M.

“…•This Clinical Practice Guideline provides recommendations for managing leptomeningeal metastases from solid tumours.•The guideline covers clinical, imaging…”
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Enhancing predictability of IDH mutation status in glioma patients at initial diagnosis: a comparative analysis of radiomics from MRI, [18F]FET PET, and TSPO PET by Kaiser, Lena, Quach, S., Zounek, A. J., Wiestler, B., Zatcepin, A., Holzgreve, A., Bollenbacher, A., Bartos, L. M., Ruf, V. C., Böning, G., Thon, N., Herms, J., Riemenschneider, M. J., Stöcklein, S., Brendel, M., Rupprecht, R., Tonn, J. C., Bartenstein, P., von Baumgarten, L., Ziegler, S., Albert, N. L.

“…Purpose According to the World Health Organization classification for tumors of the central nervous system, mutation status of the isocitrate dehydrogenase (…”
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Mutational signature of extracranial meningioma metastases and their respective primary tumors by Biczok, A, Thorsteinsdottir, J, Karschnia, P, Ruf, V C, Tonn, J C, Herms, J, Schichor, C, Dorostkar, M M

“…Extracranial metastases of intracranial meningiomas are rare. Little is known about the mutational pattern of these tumors and their metastatic seeding. Here,…”
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DNA methylation, transcriptome and genetic copy number signatures of diffuse cerebral WHO grade II/III gliomas resolve cancer heterogeneity and development by Binder, H, Willscher, E, Loeffler-Wirth, H, Hopp, L, Jones, D T W, Pfister, S M, Kreuz, M, Gramatzki, D, Fortenbacher, E, Hentschel, B, Tatagiba, M, Herrlinger, U, Vatter, H, Matschke, J, Westphal, M, Krex, D, Schackert, G, Tonn, J C, Schlegel, U, Steiger, H-J, Wick, W, Weber, R G, Weller, M, Loeffler, M

“…Diffuse lower WHO grade II and III gliomas (LGG) are slowly progressing brain tumors, many of which eventually transform into a more aggressive type. LGG is…”
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Serial stereotactic biopsy of brainstem lesions in adults improves diagnostic accuracy compared with MRI only by Rachinger, W, Grau, S, Holtmannspötter, M, Herms, J, Tonn, J-C, Kreth, F W

“…Objective:The aim of the current prospective study was to analyse the validity of MRI based diagnosis of brainstem gliomas which was verified by stereotactic…”
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Patterns, predictors and prognostic relevance of high-grade hematotoxicity after temozolomide or temozolomide-lomustine in the CeTeG/NOA-09 trial by Weller, J., Schäfer, N., Schaub, C., Tzaridis, T., Zeyen, T., Schneider, M., Potthoff, A. L., Giordano, F. A., Steinbach, J. P., Zeiner, P. S., Kowalski, T., Sabel, M., Hau, P., Krex, D., Grauer, O., Goldbrunner, R., Schnell, O., Tabatabai, G., Ringel, F., Schmidt-Graf, F., Brehmer, S., Tonn, J. C., Bullinger, L., Vajkoczy, P., Glas, M., Vatter, H., Herrlinger, U., Seidel, C.

“…Purpose In the randomized phase III trial CeTeG/NOA-09, temozolomide (TMZ)/lomustine (CCNU) combination therapy was superior to TMZ in newly diagnosed MGMT…”
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Personalized surgical therapy by Tonn, J-C, Thon, N, Schnell, O, Kreth, F W

“…Gliomas are more or less diffuse tumours with the ability to infiltrate surrounding functional brain tissue. Thus, curative surgical treatment generally cannot…”
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Fourth update of the guidelines on determination of irreversible brain death. Procedural course and amendments by Tonn, J-C

“…In 2015 the fourth update of the directive for the determination of definitely irreversible loss of complete function of the cerebrum, cerebellum and brainstem…”
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Bevacizumab can induce reactivity to VEGF-C and -D in human brain and tumour derived endothelial cells by Grau, S., Thorsteinsdottir, J., von Baumgarten, L., Winkler, F., Tonn, J.-C., Schichor, C.

“…Though clinical trials demonstrated effectiveness of the anti-VEGF antibody bevacizumab (Avastin) in adjuvant therapies for some solid tumours, there are…”
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Multicentre phase II studies evaluating imatinib plus hydroxyurea in patients with progressive glioblastoma by Reardon, D A, Dresemann, G, Taillibert, S, Campone, M, van den Bent, M, Clement, P, Blomquist, E, Gordower, L, Schultz, H, Raizer, J, Hau, P, Easaw, J, Gil, M, Tonn, J, Gijtenbeek, A, Schlegel, U, Bergstrom, P, Green, S, Weir, A, Nikolova, Z

“…Background: We evaluated the efficacy of imatinib mesylate in addition to hydroxyurea in patients with recurrent glioblastoma (GBM) who were either on or not…”
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Deletions of AXIN1, a component of the WNT/wingless pathway, in sporadic medulloblastomas by DAHMEN, R. P, KOCH, A, DENKHAUS, D, TONN, J. C, SÖRENSEN, N, BERTHOLD, F, BEHRENS, J, BIRCHMEIER, W, WIESTLER, O. D, PIETSCH, T

“…Medulloblastoma (MB) represents the most frequent malignant brain tumor in children. Most MBs appear sporadically; however, their incidence is highly elevated…”
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TSPO PET, tumour grading and molecular genetics in histologically verified glioma: a correlative 18F-GE-180 PET study by Unterrainer, M., Fleischmann, D. F., Vettermann, F., Ruf, V., Kaiser, L., Nelwan, D., Lindner, S., Brendel, M., Wenter, V., Stöcklein, S., Herms, J., Milenkovic, V. M., Rupprecht, R., Tonn, J. C., Belka, C., Bartenstein, P., Niyazi, M., Albert, N. L.

“…Background The 18-kDa translocator protein (TSPO) is overexpressed in brain tumours and represents an interesting target for glioma imaging. 18 F-GE-180, a…”
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Sexual Activity, Function, and Satisfaction in Reproductive-Aged Females Living with Chronic Kidney Disease by Corbett, Kathryn S, Chang, Danica H, Riehl-Tonn, Victoria J, Ahmed, Sofia B, Rao, Neha, Kamar, Fareed, Dumanski, Sandra M

“…Up to 80% of women living with chronic kidney disease (CKD) experience sexual dysfunction, though its link with sexual activity and sexual satisfaction is not…”
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Value of O-(2-[18F]fluoroethyl)- L-tyrosine PET for the diagnosis of recurrent glioma by Pöpperl, Gabriele, Götz, Claudia, Rachinger, Walter, Gildehaus, Franz-Josef, Tonn, Jörg-Christian, Tatsch, Klaus

“…The prognosis of patients with recurrent gliomas depends on reliable and early diagnosis of tumour recurrence after initial therapy. In this context, magnetic…”
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