Search Results - "Tonks, N. K."

Structural and Evolutionary Relationships among Protein Tyrosine Phosphatase Domains by Andersen, Jannik N., Mortensen, Ole H., Peters, Günther H., Drake, Paul G., Iversen, Lars F., Olsen, Ole H., Jansen, Peter G., Andersen, Henrik S., Tonks, Nicholas K., Møller, Niels Peter H.

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Protein Tyrosine Phosphatases: A Diverse Family of Intracellular and Transmembrane Enzymes by Fischer, E. H., Charbonneau, H., Tonks, N. K.

“…Protein tyrosine phosphatases (PTPs) represent a diverse family of enzymes that exist as integral membrane and nonreceptor forms. The PTPs, with specific…”
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Regulation of Distinct Stages of Skeletal Muscle Differentiation by Mitogen-Activated Protein Kinases by Bennett, Anton M., Tonks, Nicholas K.

“…The signal transduction pathway or pathways linking extracellular signals to myogenesis are poorly defined. Upon mitogen withdrawal from C2C12 myoblasts, the…”
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Structural Basis for Phosphotyrosine Peptide Recognition by Protein Tyrosine Phosphatase 1B by Jia, Zongchao, Barford, David, Flint, Andrew J., Tonks, Nicholas K.

“…The crystal structures of a cysteine-215 → serine mutant of protein tyrosine phosphatase 1B complexed with high-affinity peptide substrates corresponding to an…”
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MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo by Sun, H, Charles, C H, Lau, L F, Tonks, N K

“…Mitogenic stimulation of cells induces rapid and transient activation of MAP kinases. Here we report that a growth factor-inducible gene, 3CH134, encodes a…”
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Crystal Structure of Human Protein Tyrosine Phosphatase 1B by Barford, David, Flint, Andrew J., Tonks, Nicholas K.

“…Protein tyrosine phosphatases (PTPs) constitute a family of receptor-like and cytoplasmic signal transducing enzymes that catalyze the dephosphorylation of…”
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Identification of p130(cas) as a substrate for the cytosolic protein tyrosine phosphatase PTP-PEST by Garton, A J, Flint, A J, Tonks, N K

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Homophilic Binding of PTPμ, a Receptor-Type Protein Tyrosine Phosphatase, Can Mediate Cell-Cell Aggregation by Brady-Kalnay, Susann M., Flint, Andrew J., Tonks, Nicholas K.

“…The receptor-like protein tyrosine phosphatase, PTPμ, displays structural similarity to cell-cell adhesion molecules of the immunoglobulin superfamily. We have…”
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PTEN: Sometimes Taking It Off Can Be Better than Putting It On by Myers, Michael P., Tonks, Nicholas K.

“…One of the markers commonly used to identify tumor-suppressor genes is the frequent loss of heterozygosity (LOH) at a particular locus in tumor samples,…”
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Purification of the major protein-tyrosine-phosphatases of human placenta by Tonks, N K, Diltz, C D, Fischer, E H

“…This report describes the purification of the major protein-tyrosine-phosphatases from human placenta. Enzyme activity was followed with a novel artificial…”
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The Growth Factor-Inducible Immediate-Early Gene 3CH134 Encodes a Protein- Tyrosine-Phosphatase by Charles, Catherine H., Sun, Hong, Lau, Lester F., Tonks, Nicholas K.

“…Stimulation of fibroblasts with serum growth factors results in the rapid activation of a set of immediate-early genes, among them 3CH134. We have purified a…”
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Characterization of the major protein-tyrosine-phosphatases of human placenta by Tonks, N K, Diltz, C D, Fischer, E H

“…In the preceding article (Tonks, N. K., Diltz, C. D., and Fischer, E. H. (1988) J. Biol. Chem. 263, 6722-6730), the purification of the major…”
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Inhibition of Ras-Induced DNA Synthesis by Expression of the Phosphatase MKP-1 by Sun, Hong, Tonks, Nicholas K., Bar-Sagi, Dafna

“…Mitogen-activated protein kinases (MAP kinases) are common components of signaling pathways induced by diverse growth stimuli. Although the guanidine…”
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The Leukocyte Common Antigen (CD45): A Putative Receptor-Linked Protein Tyrosine Phosphatase by Charbonneau, Harry, Tonks, Nicholas K., Walsh, Kenneth A., Fischer, Edmond H.

“…A major protein tyrosine phosphatase (PTPase 1B) has been isolated in essentially homogeneous form from the soluble and particulate fractions of human…”
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Expression of DEP-1, A Receptor-Like Protein-Tyrosine-Phosphatase, is Enhanced with Increasing Cell Density by Östman, Arne, Yang, Qing, Tonks, Nicholas K.

“…cDNA encoding a receptor-like protein-tyrosine-phosphatase (PTP) termed DEP-1 was isolated from a HeLa cell library. The cDNA predicts an enzyme consisting of…”
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cDNA Isolated from a Human T-Cell Library Encodes a Member of the Protein-Tyrosine-Phosphatase Family by Cool, Deborah E., Tonks, Nicholas K., Charbonneau, Harry, Walsh, Kenneth A., Fischer, Edmond H., Krebs, Edwin G.

“…A human peripheral T-cell cDNA library was screened with two labeled synthetic oligonucleotides encoding regions of a human placenta…”
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Differential activities of protein tyrosine phosphatases in intact cells by Lammers, R, Bossenmaier, B, Cool, D.E., Tonks, N.K., Schlessinger, J, Fischer, E.H., Ullrich, A

“…We have employed transient co-overexpression of protein tyrosine phosphatases (PTPs) with a panel of receptor tyrosine kinases (RTKs) to investigate molecular…”
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Constitutive MAP kinase phosphatase (MKP-1) expression blocks G1 specific gene transcription and S-phase entry in fibroblasts by Brondello, J M, McKenzie, F R, Sun, H, Tonks, N K, Pouysségur, J

“…MAP kinase (mitogen activated protein kinase) represents a ubiquitously expressed family of kinases whose long term activation via phosphorylation is essential…”
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The Caenorhabditis elegans SH2 domain-containing protein tyrosine phosphatase PTP-2 participates in signal transduction during oogenesis and vulval development by Gutch, M J, Flint, A J, Keller, J, Tonks, N K, Hengartner, M O

“…Src homology-2 (SH2) domain-containing protein tyrosine phosphatases (SHPs) have been identified as either positive or negative regulators of signaling events…”
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CD45 Regulates Signal Transduction and Lymphocyte Activation by Specific Association with Receptor Molecules on T or B Cells by Ledbetter, Jeffrey A., Tonks, Nicholas K., Fischer, Edmond H., Clark, Edward A.

“…Evidence is presented that the leukocyte common antigen CD45 can regulate both signal transduction by lymphocyte receptor molecules and T- and B-cell…”
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