Search Results - "Tonkin, Louise M."

The Shwachman-Bodian-Diamond syndrome protein mediates translational activation of ribosomes in yeast by Tonkin, Louise M, Brost, Renée L, Menne, Tobias F, Warren, Alan J, Ancliff, Philip J, Costanzo, Michael, Sánchez-Puig, Nuria, Goyenechea, Beatriz, Boone, Charles, Wong, Chi C

“…The autosomal recessive disorder Shwachman-Diamond syndrome, characterized by bone marrow failure and leukemia predisposition, is caused by deficiency of the…”
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Mycobacterial Ku and Ligase Proteins Constitute a Two-Component NHEJ Repair Machine by Della, Marina, Palmbos, Phillip L., Tseng, Hui-Min, Tonkin, Louise M., Daley, James M., Topper, Leana M., Pitcher, Robert S., Tomkinson, Alan E., Wilson, Thomas E., Doherty, Aidan J.

“…In mammalian cells, repair of DNA double-strand breaks (DSBs) by nonhomologous end-joining (NHEJ) is critical for genome stability. Although the end-bridging…”
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Identification of a DNA Nonhomologous End-Joining Complex in Bacteria by Weller, Geoffrey R., Kysela, Boris, Roy, Rajat, Tonkin, Louise M., Scanlan, Elizabeth, Della, Marina, Devine, Susanne Krogh, Day, Jonathan P., Wilkinson, Adam, Fabrizio d'Adda di Fagagna, Devine, Kevin M., Bowater, Richard P., Jeggo, Penny A., Jackson, Stephen P., Doherty, Aidan J.

“…In eukaryotic cells, double-strand breaks (DSBs) in DNA are generally repaired by the pathway of homologous recombination or by DNA nonhomologous end joining…”
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Molecular basis of USP7 inhibition by selective small-molecule inhibitors by Turnbull, Andrew P., Ioannidis, Stephanos, Krajewski, Wojciech W., Pinto-Fernandez, Adan, Heride, Claire, Martin, Agnes C. L., Tonkin, Louise M., Townsend, Elizabeth C., Buker, Shane M., Lancia, David R., Caravella, Justin A., Toms, Angela V., Charlton, Thomas M., Lahdenranta, Johanna, Wilker, Erik, Follows, Bruce C., Evans, Nicola J., Stead, Lucy, Alli, Cristina, Zarayskiy, Vladislav V., Talbot, Adam C., Buckmelter, Alexandre J., Wang, Minghua, McKinnon, Crystal L., Saab, Fabienne, McGouran, Joanna F., Century, Hannah, Gersch, Malte, Pittman, Marc S., Marshall, C. Gary, Raynham, Tony M., Simcox, Mary, Stewart, Lorna M. D., McLoughlin, Sheila B., Escobedo, Jaime A., Bair, Kenneth W., Dinsmore, Christopher J., Hammonds, Tim R., Kim, Sunkyu, Urbé, Sylvie, Clague, Michael J., Kessler, Benedikt M., Komander, David

“…Ubiquitination controls the stability of most cellular proteins, and its deregulation contributes to human diseases including cancer. Deubiquitinases remove…”
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Solution structure of the nonmethyl-CpG-binding CXXC domain of the leukaemia-associated MLL histone methyltransferase by Allen, Mark D, Grummitt, Charles G, Hilcenko, Christine, Min, Sandra Young, Tonkin, Louise M, Johnson, Christopher M, Freund, Stefan M, Bycroft, Mark, Warren, Alan J

“…Methylation of CpG dinucleotides is the major epigenetic modification of mammalian genomes, critical for regulating chromatin structure and gene activity. The…”
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Domain Structure of a NHEJ DNA Repair Ligase from Mycobacterium tuberculosis by Pitcher, Robert S., Tonkin, Louise M., Green, Andrew J., Doherty, Aidan J.

“…A prokaryotic non-homologous end-joining (NHEJ) system for the repair of DNA double-strand breaks (DSBs), composed of a Ku homodimer (Mt-Ku) and a multidomain…”
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Mycobacteriophage Exploit NHEJ to Facilitate Genome Circularization by Pitcher, Robert S., Tonkin, Louise M., Daley, James M., Palmbos, Phillip L., Green, Andrew J., Velting, Tricia L., Brzostek, Anna, Korycka-Machala, Malgorzata, Cresawn, Steve, Dziadek, Jaroslaw, Hatfull, Graham F., Wilson, Thomas E., Doherty, Aidan J.

“…Ku-dependent nonhomologous end joining (NHEJ) is a double-strand break repair process conserved in all branches of cellular life but has not previously been…”
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