Search Results - "Tonjes, Martje"

Frequent ATRX mutations and loss of expression in adult diffuse astrocytic tumors carrying IDH1/IDH2 and TP53 mutations by Liu, Xiao-Yang, Gerges, Noha, Korshunov, Andrey, Sabha, Nesrin, Khuong-Quang, Dong-Anh, Fontebasso, Adam M., Fleming, Adam, Hadjadj, Djihad, Schwartzentruber, Jeremy, Majewski, Jacek, Dong, Zhifeng, Siegel, Peter, Albrecht, Steffen, Croul, Sidney, Jones, David TW, Kool, Marcel, Tonjes, Martje, Reifenberger, Guido, Faury, Damien, Zadeh, Gelareh, Pfister, Stefan, Jabado, Nada

“…Gliomas are the most common primary brain tumors in children and adults. We recently identified frequent alterations in chromatin remodelling pathways…”
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The cardiac transcription network modulated by Gata4, Mef2a, Nkx2.5, Srf, histone modifications, and microRNAs by Schlesinger, Jenny, Schueler, Markus, Grunert, Marcel, Fischer, Jenny J, Zhang, Qin, Krueger, Tammo, Lange, Martin, Tönjes, Martje, Dunkel, Ilona, Sperling, Silke R

“…The transcriptome, as the pool of all transcribed elements in a given cell, is regulated by the interaction between different molecular levels, involving…”
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Phosphorylation of the chromatin remodeling factor DPF3a induces cardiac hypertrophy through releasing HEY repressors from DNA by Cui, Huanhuan, Schlesinger, Jenny, Schoenhals, Sophia, Tönjes, Martje, Dunkel, Ilona, Meierhofer, David, Cano, Elena, Schulz, Kerstin, Berger, Michael F, Haack, Timm, Abdelilah-Seyfried, Salim, Bulyk, Martha L, Sauer, Sascha, Sperling, Silke R

“…DPF3 (BAF45c) is a member of the BAF chromatin remodeling complex. Two isoforms have been described, namely DPF3a and DPF3b. The latter binds to acetylated and…”
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Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex by Lange, Martin, Kaynak, Bogac, Forster, Ulrike B, Tönjes, Martje, Fischer, Jenny J, Grimm, Christina, Schlesinger, Jenny, Just, Steffen, Dunkel, Ilona, Krueger, Tammo, Mebus, Siegrun, Lehrach, Hans, Lurz, Rudi, Gobom, Johan, Rottbauer, Wolfgang, Abdelilah-Seyfried, Salim, Sperling, Silke

“…Chromatin remodeling and histone modifications facilitate access of transcription factors to DNA by promoting the unwinding and destabilization of histone-DNA…”
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BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation by Raffel, Simon, Falcone, Mattia, Kneisel, Niclas, Hansson, Jenny, Wang, Wei, Lutz, Christoph, Bullinger, Lars, Poschet, Gernot, Nonnenmacher, Yannic, Barnert, Andrea, Bahr, Carsten, Zeisberger, Petra, Przybylla, Adriana, Sohn, Markus, Tönjes, Martje, Erez, Ayelet, Adler, Lital, Jensen, Patrizia, Scholl, Claudia, Fröhling, Stefan, Cocciardi, Sibylle, Wuchter, Patrick, Thiede, Christian, Flörcken, Anne, Westermann, Jörg, Ehninger, Gerhard, Lichter, Peter, Hiller, Karsten, Hell, Rüdiger, Herrmann, Carl, Ho, Anthony D., Krijgsveld, Jeroen, Radlwimmer, Bernhard, Trumpp, Andreas

“…The mechanistic basis for the role of the metabolic enzyme BCAA transaminase 1 (BCAT1) in acute myeloid leukaemias. BCAT1 behind DNA hypermethylation…”
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Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma by Sturm, Dominik, Witt, Hendrik, Hovestadt, Volker, Khuong-Quang, Dong-Anh, Jones, David T.W., Konermann, Carolin, Pfaff, Elke, Tönjes, Martje, Sill, Martin, Bender, Sebastian, Kool, Marcel, Zapatka, Marc, Becker, Natalia, Zucknick, Manuela, Hielscher, Thomas, Liu, Xiao-Yang, Fontebasso, Adam M., Ryzhova, Marina, Albrecht, Steffen, Jacob, Karine, Wolter, Marietta, Ebinger, Martin, Schuhmann, Martin U., van Meter, Timothy, Frühwald, Michael C., Hauch, Holger, Pekrun, Arnulf, Radlwimmer, Bernhard, Niehues, Tim, von Komorowski, Gregor, Dürken, Matthias, Kulozik, Andreas E., Madden, Jenny, Donson, Andrew, Foreman, Nicholas K., Drissi, Rachid, Fouladi, Maryam, Scheurlen, Wolfram, von Deimling, Andreas, Monoranu, Camelia, Roggendorf, Wolfgang, Herold-Mende, Christel, Unterberg, Andreas, Kramm, Christof M., Felsberg, Jörg, Hartmann, Christian, Wiestler, Benedikt, Wick, Wolfgang, Milde, Till, Witt, Olaf, Lindroth, Anders M., Schwartzentruber, Jeremy, Faury, Damien, Fleming, Adam, Zakrzewska, Magdalena, Liberski, Pawel P., Zakrzewski, Krzysztof, Hauser, Peter, Garami, Miklos, Klekner, Almos, Bognar, Laszlo, Morrissy, Sorana, Cavalli, Florence, Taylor, Michael D., van Sluis, Peter, Koster, Jan, Versteeg, Rogier, Volckmann, Richard, Mikkelsen, Tom, Aldape, Kenneth, Reifenberger, Guido, Collins, V. Peter, Majewski, Jacek, Korshunov, Andrey, Lichter, Peter, Plass, Christoph, Jabado, Nada, Pfister, Stefan M.

“…Glioblastoma (GBM) is a brain tumor that carries a dismal prognosis and displays considerable heterogeneity. We have recently identified recurrent H3F3A…”
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Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma by Schwartzentruber, Jeremy, Korshunov, Andrey, Liu, Xiao-Yang, Jones, David T. W., Pfaff, Elke, Jacob, Karine, Sturm, Dominik, Fontebasso, Adam M., Quang, Dong-Anh Khuong, Tönjes, Martje, Hovestadt, Volker, Albrecht, Steffen, Kool, Marcel, Nantel, Andre, Konermann, Carolin, Lindroth, Anders, Jäger, Natalie, Rausch, Tobias, Ryzhova, Marina, Korbel, Jan O., Hielscher, Thomas, Hauser, Peter, Garami, Miklos, Klekner, Almos, Bognar, Laszlo, Ebinger, Martin, Schuhmann, Martin U., Scheurlen, Wolfram, Pekrun, Arnulf, Frühwald, Michael C., Roggendorf, Wolfgang, Kramm, Christoph, Dürken, Matthias, Atkinson, Jeffrey, Lepage, Pierre, Montpetit, Alexandre, Zakrzewska, Magdalena, Zakrzewski, Krzystof, Liberski, Pawel P., Dong, Zhifeng, Siegel, Peter, Kulozik, Andreas E., Zapatka, Marc, Guha, Abhijit, Malkin, David, Felsberg, Jörg, Reifenberger, Guido, von Deimling, Andreas, Ichimura, Koichi, Collins, V. Peter, Witt, Hendrik, Milde, Till, Witt, Olaf, Zhang, Cindy, Castelo-Branco, Pedro, Lichter, Peter, Faury, Damien, Tabori, Uri, Plass, Christoph, Majewski, Jacek, Pfister, Stefan M., Jabado, Nada

“…Recurrent histone mutations are linked to paediatric glioblastoma multiforme, an aggressive type of brain tumour. Drug targets in glioblastoma Exome sequencing…”
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BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1 by Tönjes, Martje, Barbus, Sebastian, Park, Yoon Jung, Wang, Wei, Schlotter, Magdalena, Lindroth, Anders M, Pleier, Sabrina V, Bai, Alfa H C, Karra, Daniela, Piro, Rosario M, Felsberg, Jörg, Addington, Adele, Lemke, Dieter, Weibrecht, Irene, Hovestadt, Volker, Rolli, Claudio G, Campos, Benito, Turcan, Sevin, Sturm, Dominik, Witt, Hendrik, Chan, Timothy A, Herold-Mende, Christel, Kemkemer, Ralf, König, Rainer, Schmidt, Kathrin, Hull, William-Edmund, Pfister, Stefan M, Jugold, Manfred, Hutson, Susan M, Plass, Christoph, Okun, Jürgen G, Reifenberger, Guido, Lichter, Peter, Radlwimmer, Bernhard

“…Branched-chain amino acid transaminase 1, the enzyme that initiates the catabolism of branched-chain amino acids, is involved in glioma pathogenesis, making it…”
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Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma by Schwartzentruber, Jeremy, Korshunov, Andrey, Liu, Xiao-Yang, Jones, David T.W, Pfaff, Elke, Jacob, Karine, Sturm, Dominik, Fontebasso, Adam M, Quang, Dong-Anh Khuong, Tonjes, Martje, Hovestadt, Volker, Albrecht, Steffen, Kool, Marcel, Nantel, Andre, Konermann, Carolin, Lindroth, Anders, Jager, Natalie, Rausch, Tobias, Ryzhova, Marina, Korbel, Jan O, Hielscher, Thomas, Hauser, Peter, Garami, Miklos, Klekner, Almos, Bognar, Laszlo, Ebinger, Martin, Schuhmann, Martin U, Scheurlen, Wolfram, Pekrun, Arnulf, Fruhwald, Michael C, Roggendorf, Wolfgang, Kramm, Christoph, Durken, Matthias, Atkinson, Jeffrey, Lepage, Pierre, Montpetit, Alexandre, Zakrzewska, Magdalena, Zakrzewski, Krzystof, Liberski, Pawel P, Dong, Zhifeng, Siegel, Peter, Kulozik, Andreas E, Zapatka, Marc, Guha, Abhijit, Malkin, David, Felsberg, Jorg, Reifenberger, Guido, von Deimling, Andreas, Ichimura, Koichi, Collins, V. Peter, Witt, Hendrik, Milde, Till, Witt, Olaf, Zhang, Cindy, Castelo-Branco, Pedro, Lichter, Peter, Faury, Damien, Tabori, Uri, Plass, Christoph, Majewski, Jacek, Pfister, Stefan M, Jabado, Nada

“…Glioblastoma multiforme (GBM) is a lethal brain tumour in adults and children. However, DNA copy number and gene expression signatures indicate differences…”
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Author Correction: BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation by Raffel, Simon, Falcone, Mattia, Kneisel, Niclas, Hansson, Jenny, Wang, Wei, Lutz, Christoph, Bullinger, Lars, Poschet, Gernot, Nonnenmacher, Yannic, Barnert, Andrea, Bahr, Carsten, Zeisberger, Petra, Przybylla, Adriana, Sohn, Markus, Tönjes, Martje, Erez, Ayelet, Adler, Lital, Jensen, Patrizia, Scholl, Claudia, Fröhling, Stefan, Cocciardi, Sibylle, Wuchter, Patrick, Thiede, Christian, Flörcken, Anne, Westermann, Jörg, Ehninger, Gerhard, Lichter, Peter, Hiller, Karsten, Hell, Rüdiger, Herrmann, Carl, Ho, Anthony D., Krijgsveld, Jeroen, Radlwimmer, Bernhard, Trumpp, Andreas

“…In Extended Data Fig. 1a of this Letter, the flow cytometry plot depicting the surface phenotype of AML sample DD08 was a duplicate of the plot for AML sample…”
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BCAT1 restricts αKG levels in AML stem cells leading to IDH^sup mut^-like DNA hypermethylation by Raffel, Simon, Falcone, Mattia, Kneisel, Niclas, Hansson, Jenny, Wang, Wei, Lutz, Christoph, Bullinger, Lars, Poschet, Gernot, Nonnenmacher, Yannic, Barnert, Andrea, Bahr, Carsten, Zeisberger, Petra, Przybylla, Adriana, Sohn, Markus, Tönjes, Martje, Erez, Ayelet, Adler, Lital, Jensen, Patrizia, Scholl, Claudia, Fröhling, Stefan, Cocciardi, Sibylle, Wuchter, Patrick, Thiede, Christian, Flörcken, Anne, Westermann, Jörg, Ehninger, Gerhard, Lichter, Peter, Hiller, Karsten, Hell, Rüdiger, Herrmann, Carl, Ho, Anthony D, Krijgsveld, Jeroen, Radlwimmer, Bernhard, Trumpp, Andreas

“…The branched-chain amino acid (BCAA) pathway and high levels of BCAA transaminase 1 (BCAT1) have recently been associated with aggressiveness in several cancer…”
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Dynamics of Srf, p300 and histone modifications during cardiac maturation in mouse by Schueler, Markus, Zhang, Qin, Schlesinger, Jenny, Tönjes, Martje, Sperling, Silke R

“…The adaptation of the cellular network to functional changes, timing and patterning of gene expression is regulated by binding of transcription factors to gene…”
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Evaluation of the LightCycler® 1536 Instrument for high-throughput quantitative real-time PCR by Schlesinger, Jenny, Tönjes, Martje, Schueler, Markus, Zhang, Qin, Dunkel, Ilona, Sperling, Silke R.

“…Quantitative real-time PCR (qPCR) is a frequently used, sensitive and accurate method to study gene expression profiles. However, its throughput was so far…”
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The Cardiac Transcription Network Modulated by Gata4, Mef2a, Nkx2.5, Srf, Histone Modifications, and MicroRNAs: e1001313 by Schlesinger, Jenny, Schueler, Markus, Grunert, Marcel, Fischer, Jenny J, Zhang, Qin, Krueger, Tammo, Lange, Martin, Tönjes, Martje, Dunkel, Ilona, Sperling, Silke R

“…The transcriptome, as the pool of all transcribed elements in a given cell, is regulated by the interaction between different molecular levels, involving…”
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Author Correction: BCAT1 restricts αKG levels in AML stem cells leading to IDH mut -like DNA hypermethylation by Raffel, Simon, Falcone, Mattia, Kneisel, Niclas, Hansson, Jenny, Wang, Wei, Lutz, Christoph, Bullinger, Lars, Poschet, Gernot, Nonnenmacher, Yannic, Barnert, Andrea, Bahr, Carsten, Zeisberger, Petra, Przybylla, Adriana, Sohn, Markus, Tönjes, Martje, Erez, Ayelet, Adler, Lital, Jensen, Patrizia, Scholl, Claudia, Fröhling, Stefan, Cocciardi, Sibylle, Wuchter, Patrick, Thiede, Christian, Flörcken, Anne, Westermann, Jörg, Ehninger, Gerhard, Lichter, Peter, Hiller, Karsten, Hell, Rüdiger, Herrmann, Carl, Ho, Anthony D, Krijgsveld, Jeroen, Radlwimmer, Bernhard, Trumpp, Andreas

“…In Extended Data Fig. 1a of this Letter, the flow cytometry plot depicting the surface phenotype of AML sample DD08 was a duplicate of the plot for AML sample…”
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Correction: Corrigendum: Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma by Schwartzentruber, Jeremy, Korshunov, Andrey, Liu, Xiao-Yang, Jones, David T. W., Pfaff, Elke, Jacob, Karine, Sturm, Dominik, Fontebasso, Adam M., Quang, Dong-Anh Khuong, Tönjes, Martje, Hovestadt, Volker, Albrecht, Steffen, Kool, Marcel, Nantel, Andre, Konermann, Carolin, Lindroth, Anders, Jäger, Natalie, Rausch, Tobias, Ryzhova, Marina, Korbel, Jan O., Hielscher, Thomas, Hauser, Peter, Garami, Miklos, Klekner, Almos, Bognar, Laszlo, Ebinger, Martin, Schuhmann, Martin U., Scheurlen, Wolfram, Pekrun, Arnulf, Frühwald, Michael C., Roggendorf, Wolfgang, Kramm, Christoph, Dürken, Matthias, Atkinson, Jeffrey, Lepage, Pierre, Montpetit, Alexandre, Zakrzewska, Magdalena, Zakrzewski, Krzystof, Liberski, Pawel P., Dong, Zhifeng, Siegel, Peter, Kulozik, Andreas E., Zapatka, Marc, Guha, Abhijit, Malkin, David, Felsberg, Jörg, Reifenberger, Guido, von Deimling, Andreas, Ichimura, Koichi, Collins, V. Peter, Witt, Hendrik, Milde, Till, Witt, Olaf, Zhang, Cindy, Castelo-Branco, Pedro, Lichter, Peter, Faury, Damien, Tabori, Uri, Plass, Christoph, Majewski, Jacek, Pfister, Stefan M., Jabado, Nada

“…Nature 482, 226–231 (2012) Sequence reads for paediatric glioblastoma multiforme (GBM) samples have been deposited in the European Genome Archive under the…”
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Erratum: Corrigendum: Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma by Schwartzentruber, Jeremy, Korshunov, Andrey, Liu, Xiao-Yang, Jones, David T. W., Pfaff, Elke, Jacob, Karine, Sturm, Dominik, Fontebasso, Adam M., Quang, Dong-Anh Khuong, Tönjes, Martje, Hovestadt, Volker, Albrecht, Steffen, Kool, Marcel, Nantel, Andre, Konermann, Carolin, Lindroth, Anders, Jäger, Natalie, Rausch, Tobias, Ryzhova, Marina, Korbel, Jan O., Hielscher, Thomas, Hauser, Peter, Garami, Miklos, Klekner, Almos, Bognar, Laszlo, Ebinger, Martin, Schuhmann, Martin U., Scheurlen, Wolfram, Pekrun, Arnulf, Frühwald, Michael C., Roggendorf, Wolfgang, Kramm, Christoph, Dürken, Matthias, Atkinson, Jeffrey, Lepage, Pierre, Montpetit, Alexandre, Zakrzewska, Magdalena, Zakrzewski, Krzystof, Liberski, Pawel P., Dong, Zhifeng, Siegel, Peter, Kulozik, Andreas E., Zapatka, Marc, Guha, Abhijit, Malkin, David, Felsberg, Jörg, Reifenberger, Guido, von Deimling, Andreas, Ichimura, Koichi, Collins, V. Peter, Witt, Hendrik, Milde, Till, Witt, Olaf, Zhang, Cindy, Castelo-Branco, Pedro, Lichter, Peter, Faury, Damien, Tabori, Uri, Plass, Christoph, Majewski, Jacek, Pfister, Stefan M., Jabado, Nada

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Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma by SCHWARTZENTRUBER, Jeremy, KORSHUNOV, Andrey, HOVESTADT, Volker, ALBRECHT, Steffen, KOOL, Marcel, NANTEL, Andre, KONERMARM, Carolin, LINDROTH, Anders, JÄGER, Natalie, RAUSCH, Tobias, RYZHOVA, Marina, KORBEL, Jan O, LIU, Xiao-Yang, HIELSCHER, Thomas, HAUSER, Peter, GARAMI, Miklos, KLEKNER, Almos, BOGNAR, Laszlo, EBINGER, Martin, SCHUHMANN, Martin U, SCHEURLEN, Wolfram, PEKRUN, Arnulf, FRÜHWALD, Michael C, JONES, David T. W, ROGGENDORF, Wolfgang, KRAMM, Christoph, DÜRKEN, Matthias, ATKINSON, Jeffrey, LEPAGE, Pierre, MONTPETIT, Alexandre, ZAKRZEWSKA, Magdalena, ZAKRZEWSKI, Krzystof, LIBERSKI, Pawel P, ZHIFENG DONG, PFAFF, Elke, SIEGEL, Peter, KULOZIK, Andreas E, ZAPATKA, Marc, GUHA, Abhijit, MALKIN, David, FELSBERG, Jörg, REIFENBERGER, Guido, VON DEIMLING, Andreas, ICHIMURA, Koichi, COLLINS, V. Peter, JACOB, Karine, WITT, Hendrik, MILDE, Till, WITT, Olaf, ZHANG, Cindy, CASTELO-BRANCO, Pedro, LICHTER, Peter, FAURY, Damien, TABORI, Uri, PLASS, Christoph, MAJEWSKI, Jacek, STURM, Dominik, FONTEBASSO, Adam M, KHUONG QUANG, Dong-Anh, TÖNJES, Martje

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