Search Results - "Toninello, A"

Early effects of the antineoplastic agent salinomycin on mitochondrial function by Managò, A, Leanza, L, Carraretto, L, Sassi, N, Grancara, S, Quintana-Cabrera, R, Trimarco, V, Toninello, A, Scorrano, L, Trentin, L, Semenzato, G, Gulbins, E, Zoratti, M, Szabò, I

“…Salinomycin, isolated from Streptomyces albus , displays antimicrobial activity. Recently, a large-scale screening approach identified salinomycin and…”
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Polyamines: fundamental characters in chemistry and biology by Agostinelli, E., Marques, M. P. M., Calheiros, R., Gil, F. P. S. C., Tempera, G., Viceconte, N., Battaglia, V., Grancara, S., Toninello, A.

“…Polyamines are small cationic molecules required for cellular proliferation and are detected at higher concentrations in most tumour tissues, compared to…”
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Potential anticancer application of polyamine oxidation products formed by amine oxidase: a new therapeutic approach by Agostinelli, E, Tempera, G, Viceconte, N, Saccoccio, S, Battaglia, V, Grancara, S, Toninello, A, Stevanato, R

“…The polyamines spermine, spermidine and putrescine are ubiquitous cell components. These molecules are substrates of a class of enzymes that includes monoamine…”
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Interaction of biologically active amines with mitochondria and their role in the mitochondrial-mediated pathway of apoptosis by Toninello, A, Salvi, M, Mondovì, B

“…The natural polyamines spermine, spermidine and putrescine, polycationic molecules at physiological pH, interact with mitochondrial membranes at two specific…”
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Agmatine prevents the Ca(2+)-dependent induction of permeability transition in rat brain mitochondria by Battaglia, V, Grancara, S, Satriano, J, Saccoccio, S, Agostinelli, E, Toninello, A

“…The arginine metabolite agmatine is able to protect brain mitochondria against the drop in energy capacity by the Ca(2+)-dependent induction of permeability…”
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Anti-inflammatory and antiproliferative evaluation of 4β-cinnamoyloxy,1β,3α-dihydroxyeudesm-7,8-ene from Verbesina persicifolia and derivatives by Dalla Via, L., Mejia, M., García-Argáez, A.N., Braga, A., Toninello, A., Martínez-Vázquez, M.

“…[Display omitted] The anti-inflammatory and antiproliferative activities of 4β-cinnamoyloxy,1β,3α-dihydroxyeudesm-7,8-ene (1) and of three derivatives, namely…”
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Agmatine prevents the Ca²⁺-dependent induction of permeability transition in rat brain mitochondria by Battaglia, V, Grancara, S, Satriano, J, Saccoccio, S, Agostinelli, E, Toninello, A

“…The arginine metabolite agmatine is able to protect brain mitochondria against the drop in energy capacity by the Ca²⁺-dependent induction of permeability…”
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Design and Synthesis of New Bifunctional Sigma‑1 Selective Ligands with Antioxidant Activity by Prezzavento, O, Arena, E, Parenti, C, Pasquinucci, L, Aricò, G, Scoto, G. M, Grancara, S, Toninello, A, Ronsisvalle, S

“…Herein we report the synthesis of new bifunctional sigma-1 (σ1)-selective ligands with antioxidant activity. To achieve this goal, we combined the structure of…”
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The biological functions of polyamine oxidation products by amine oxidases: perspectives of clinical applications by Agostinelli, E, Arancia, G, Vedova, L Dalla, Belli, F, Marra, M, Salvi, M, Toninello, A

“…The polyamines spermine, spermidine and putrescine are ubiquitous cell components. If they accumulate excessively within the cells, due either to very high…”
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Polyamines: fundamental characters in chemistry and biology by Agostinelli, E., Marques, M. P. M., Calheiros, R., Gil, F. P. S. C., Tempera, G., Viceconte, N., Battaglia, V., Grancara, S., Toninello, A.

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Interactions of melatonin with mammalian mitochondria. Reducer of energy capacity and amplifier of permeability transition by Martinis, P., Zago, L., Maritati, M., Battaglia, V., Grancara, S., Rizzoli, V., Agostinelli, E., Bragadin, M., Toninello, A.

“…Melatonin, a metabolic product of the amino acid tryptophan, induces a dose-dependent energy drop correlated with a decrease in the oxidative phosphorylation…”
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Different behavior of agmatine in liver mitochondria: Inducer of oxidative stress or scavenger of reactive oxygen species? by Battaglia, V., Rossi, C.A., Colombatto, S., Grillo, M.A., Toninello, A.

“…Agmatine, at concentrations of 10 μM or 100 μM, is able to induce oxidative stress in rat liver mitochondria (RLM), as evidenced by increased oxygen uptake, H…”
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Tyrosine phosphatase activity in mitochondria: presence of Shp-2 phosphatase in mitochondria by Salvi, M, Stringaro, A, Brunati, A M, Agostinelli, E, Arancia, G, Clari, G, Toninello, A

“…Tyrosine phosphorylation by unidentified enzymes has been observed in mitochondria, with recent evidence indicating that non-receptorial tyrosine kinases…”
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physiological role of biogenic amines redox reactions in mitochondria. New perspectives in cancer therapy by Agostinelli, E, Tempera, G, Molinari, A, Salvi, M, Battaglia, V, Toninello, A, Arancia, G

“…In tumours, polyamines and amine oxidases increase as compared to normal tissues. Cytotoxicity induced by bovine serum amine oxidase (BSAO) and spermine is…”
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Synthesis and biological activity of 1,4-dihydrobenzothiopyrano[4,3- c]pyrazole derivatives, novel pro-apoptotic mitochondrial targeted agents by Dalla Via, L., Marini, A.M., Salerno, S., La Motta, C., Condello, M., Arancia, G., Agostinelli, E., Toninello, A.

“…A series of new 1,4-dihydrobenzothiopyrano[4,3- c]pyrazole derivatives were synthesized. Compound 3c shows the higher antiproliferative effect on tumor cell…”
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Ca-independent effects of spermine on pyruvate dehydrogenase complex activity in energized rat liver mitochondria incubated in the absence of exogenous Ca and Mg by Pezzato, E, Battaglia, V, Brunati, A M, Agostinelli, E, Toninello, A

“…In the absence of exogenous Ca and Mg and in the presence of EGTA, which favours the release of endogenous Ca, the polyamine spermine is able to stimulate the…”
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Biogenic amines and apoptosis: minireview article by Toninello, A, Salvi, M, Pietrangeli, P, Mondovì, B

“…The programmed cell death is a very complex mechanism involving many factors, among them the intracellular concentration of biogenic amines (BA) appears to be…”
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Agmatine transport in brain mitochondria: a different mechanism from that in liver mitochondria by Battaglia, V, Grancara, S, Mancon, M, Cravanzola, C, Colombatto, S, Grillo, M. A, Tempera, G, Agostinelli, E, Toninello, A

“…The diamine agmatine (AGM), exhibiting two positive charges at physiological pH, is transported into rat brain mitochondria (RBM) by an electrophoretic…”
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Protective effect of N-(2-propynyl)-2-(5-benzyloxy-indolyl) methylamine (PF9601N) on mitochondrial permeability transition by Battaglia, V, Sanz, E, Salvi, M, Unzeta, M, Toninello, A

“…PF9601N, N-(2-propynyl)-2-(5-benzyloxy-indolyl) methylamine, an monoamine oxidase (MAO) B inhibitor, has shown neuroprotective properties against dopaminergic…”
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842 ACTIVATED SRC FAMILY KINASE LYN AS SIGNALING MOLECULE FOR MITOCHONDRIA IN EARLY LIVER REGENERATION by Gringeri, E, Carraro, A, Tibladi, E, D'Amico, F.E, Mancon, M, Toninello, A, Pagano, M, Brunati, A.M, Cillo, U

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