Search Results - "Toni, N"

The mechanisms of sorafenib resistance in hepatocellular carcinoma: theoretical basis and therapeutic aspects by Tang, Weiwei, Chen, Ziyi, Zhang, Wenling, Cheng, Ye, Zhang, Betty, Wu, Fan, Wang, Qian, Wang, Shouju, Rong, Dawei, Reiter, F. P., De Toni, E. N., Wang, Xuehao

“…Sorafenib is a multikinase inhibitor capable of facilitating apoptosis, mitigating angiogenesis and suppressing tumor cell proliferation. In late-stage…”
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Impact of combined selective internal radiation therapy and sorafenib on survival in advanced hepatocellular carcinoma by Ricke, Jens, Klümpen, Heinz Josef, Amthauer, Holger, Bargellini, Irene, Bartenstein, Peter, de Toni, Enrico N., Gasbarrini, Antonio, Pech, Maciej, Peck-Radosavljevic, Markus, Popovič, Peter, Rosmorduc, Olivier, Schott, Eckart, Seidensticker, Max, Verslype, Chris, Sangro, Bruno, Malfertheiner, Peter

“…[Display omitted] •Sorafenib given orally is the recommended treatment for patients with advanced hepatocellular carcinoma.•Addition of selective internal…”
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Synthesis and Fluorescent Properties of Alkynyl- and Alkenyl-Fused Benzotriazole-Derived α‑Amino Acids by Riley, Leanne M., Mclay, Toni N., Sutherland, Andrew

“…Fluorescent unnatural α-amino acids are widely used as probes in chemical biology and medicinal chemistry. While a variety of structural classes have been…”
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Click-to-Capture: A method for enriching viable Staphylococcus aureus using bio-orthogonal labeling of surface proteins by Shalizi, Aryaman, Wiegers, Toni N, Maamar, Hédia

“…Staphylococcus aureus is one of the principal causative agents of bacteremia which can progress to sepsis. Rapid diagnostic tests for identification and…”
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Use of checkpoint inhibitors in liver transplant recipients by Munker, Stefan, De Toni, Enrico N

“…In spite of their major impact in cancer therapy, immune checkpoint inhibitors are considered to be contraindicated in liver transplant recipients due to fear…”
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Human Adult Neurogenesis: Evidence and Remaining Questions by Kempermann, Gerd, Gage, Fred H., Aigner, Ludwig, Song, Hongjun, Curtis, Maurice A., Thuret, Sandrine, Kuhn, H. Georg, Jessberger, Sebastian, Frankland, Paul W., Cameron, Heather A., Gould, Elizabeth, Hen, Rene, Abrous, D. Nora, Toni, Nicolas, Schinder, Alejandro F., Zhao, Xinyu, Lucassen, Paul J., Frisén, Jonas

“…Renewed discussion about whether or not adult neurogenesis exists in the human hippocampus, and the nature and strength of the supporting evidence, has been…”
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Steroid hormone control of myometrial contractility and parturition by Mesiano, Sam, Welsh, Toni N.

“…The precise temporal control of uterine contractility is essential for the success of pregnancy. For most of pregnancy, progesterone acting through genomic and…”
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The role of the novel Th17 cytokine IL-26 in intestinal inflammation by Dambacher, J, Beigel, F, Zitzmann, K, De Toni, E N, Göke, B, Diepolder, H M, Auernhammer, C J, Brand, S

“…Interleukin 26 (IL-26), a novel IL-10-like cytokine without a murine homologue, is expressed in T helper 1 (Th1) and Th17 cells. Currently, its function in…”
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IL12/23 Blockade for Refractory Immune-Mediated Colitis: 2-Center Experience by Shirwaikar Thomas, Anusha, Lee, Seung Eun, Shatila, Malek, De Toni, Enrico N., Török, Helga-Paula, Ben Khaled, Najib, Powell, Nicholas, Weight, Ryan, Faleck, David M., Wang, Yinghong

“…Immune checkpoint inhibitor-mediated colitis (IMC) is commonly managed with steroids and biologics. We evaluated the efficacy of ustekinumab (UST) in treating…”
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Circadian glucocorticoid oscillations preserve a population of adult hippocampal neural stem cells in the aging brain by Schouten, M., Bielefeld, P., Garcia-Corzo, L., Passchier, E. M. J., Gradari, S., Jungenitz, T., Pons-Espinal, M., Gebara, E., Martín-Suárez, S., Lucassen, P. J., De Vries, H. E., Trejo, J. L., Schwarzacher, S. W., De Pietri Tonelli, D., Toni, N., Mira, H., Encinas, J. M., Fitzsimons, C. P.

“…A decrease in adult hippocampal neurogenesis has been linked to age-related cognitive impairment. However, the mechanisms involved in this age-related…”
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Development and characterization of a human embryonic stem cell-derived 3D neural tissue model for neurotoxicity testing by Sandström, J, Eggermann, E, Charvet, I, Roux, A, Toni, N, Greggio, C, Broyer, A, Monnet-Tschudi, F, Stoppini, L

“…Alternative models for more rapid compound safety testing are of increasing demand. With emerging techniques using human pluripotent stem cells, the…”
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Testosterone-associated blood pressure dysregulation in women with androgen excess polycystic ovary syndrome by Stone, Tori, Yanes Cardozo, Licy L, Oluwatade, Toni N, Leone, Cheryl A, Burgos, Melanie, Okifo, Faith, Pal, Lubna, Reckelhoff, Jane F, Stachenfeld, Nina S

“…We tested the hypothesis that hyperandrogenemia in androgen excess polycystic ovary syndrome (AE-PCOS) is a primary driver in blood pressure (BP) dysregulation…”
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Progesterone receptor expression declines in the guinea pig uterus during functional progesterone withdrawal and in response to prostaglandins by Welsh, Toni N, Hirst, Jonathan J, Palliser, Hannah, Zakar, Tamas

“…Progesterone withdrawal is essential for parturition, but the mechanism of this pivotal hormonal change is unclear in women and other mammals that give birth…”
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Radiofrequency ablation via catheter and transpapillary access in patients with cholangiocarcinoma (ACTICCA-2 trial) - a multicenter, randomized, controlled, open-label investigator-initiated trial by Schmidt, Constantin, Zapf, Antonia, Ozga, Ann-Kathrin, Canbay, Ali, Denzer, Ulrike, De Toni, Enrico N, Lohse, Ansgar W, Schulze, Kornelius, Rösch, Thomas, Stein, Alexander, Wege, Henning, von Felden, Johann

“…Despite the recent advances in cancer treatment, the therapeutic options for patients with biliary tract cancer are still very limited and the prognosis very…”
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Dynamics of SARS-CoV-2 shedding in the respiratory tract depends on the severity of disease in COVID-19 patients by Munker, Dieter, Osterman, Andreas, Stubbe, Hans, Muenchhoff, Maximilian, Veit, Tobias, Weinberger, Tobias, Barnikel, Michaela, Mumm, Jan-Niclas, Milger, Katrin, Khatamzas, Elham, Klauss, Sarah, Scherer, Clemens, Hellmuth, Johannes C, Giessen-Jung, Clemens, Zoller, Michael, Herold, Tobias, Stecher, Stephanie, de Toni, Enrico N, Schulz, Christian, Kneidinger, Nikolaus, Keppler, Oliver T, Behr, Jürgen, Mayerle, Julia, Munker, Stefan

“…A fraction of COVID-19 patients progress to a severe disease manifestation with respiratory failure and the necessity of mechanical ventilation. Identifying…”
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Neuronal metabolic rewiring promotes resilience to neurodegeneration caused by mitochondrial dysfunction by Motori, E, Atanassov, I, Kochan, S M V, Folz-Donahue, K, Sakthivelu, V, Giavalisco, P, Toni, N, Puyal, J, Larsson, N-G

“…Neurodegeneration in mitochondrial disorders is considered irreversible because of limited metabolic plasticity in neurons, yet the cell-autonomous…”
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Durable Complete Response of Brain Metastasis From Hepatocellular Carcinoma On Treatment With Nivolumab and Radiation Treatment by Ye, Liangtao, Zhang, Changhua, Seidensticker, Max, Mayerle, Julia, Reiter, Florian P., De Toni, Enrico N.

“…A 52-year-old male patient with active chronic hepatitis C virus infection and liver cirrhosis (he reported having undergone an unsuccessful treatment cycle of…”
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GSK-3β orchestrates the inhibitory innervation of adult-born dentate granule cells in vivo by Moreno-Jiménez, E. P., Flor-García, M., Hernández-Vivanco, A., Terreros-Roncal, J., Rodríguez-Moreno, C. B., Toni, N., Méndez, P., Llorens-Martín, María

“…Adult hippocampal neurogenesis enhances brain plasticity and contributes to the cognitive reserve during aging. Adult hippocampal neurogenesis is impaired in…”
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Nuclear Progesterone Receptors in the Human Pregnancy Myometrium: Evidence that Parturition Involves Functional Progesterone Withdrawal Mediated by Increased Expression of Progesterone Receptor-A by Merlino, Amy A., Welsh, Toni N., Tan, Huiqing, Yi, Li Juan, Cannon, Vernon, Mercer, Brian M., Mesiano, Sam

“…Context: We examined whether human parturition involves functional progesterone withdrawal mediated by changes in myometrial expression of progesterone…”
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Follistatin‐controlled activin‐HNF4α‐coagulation factor axis in liver progenitor cells determines outcome of acute liver failure by Lin, Tao, Wang, Shanshan, Munker, Stefan, Jung, Kyounghwa, Macías‐Rodríguez, Ricardo U., Ruiz‐Margáin, Astrid, Schierwagen, Robert, Liu, Hui, Shao, Chen, Fan, Chunlei, Feng, Rilu, Yuan, Xiaodong, Wang, Sai, Wandrer, Franziska, Meyer, Christoph, Wimmer, Ralf, Liebe, Roman, Kroll, Jens, Zhang, Long, Schiergens, Tobias, ten Dijke, Peter, Teufel, Andreas, Marx, Alexander, Mertens, Peter R., Wang, Hua, Ebert, Matthias P.A., Bantel, Heike, De Toni, Enrico, Trebicka, Jonel, Dooley, Steven, Shin, Donghun, Ding, Huiguo, Weng, Hong‐Lei

“…Background and Aims In patients with acute liver failure (ALF) who suffer from massive hepatocyte loss, liver progenitor cells (LPCs) take over key hepatocyte…”
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