Search Results - "Tonge, D W"

Rapid induction of IGF-IR signaling in normal and tumor tissue following intravenous injection of IGF-I in mice by Lee, A V, Taylor, S T, Greenall, J, Mills, J D, Tonge, D W, Zhang, P, George, J, Fiorotto, M L, Hadsell, D L

“…The detection of IGF-IR signaling in animal models has important implications for determining the role of this receptor in normal physiology and tumor growth…”
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Recombinant single‐chain and disulfide‐stabilized Fv‐immunotoxins that cause complete regression of a human colon cancer xenograft in nude mice by Reiter, Yoram, Wright, Andrew F., Tonge, David W., Pastan, Ira

“…Monoclonal antibody (MAb) 55.1 specifically recognizes an antigen on the surface of human colon adenocarcinoma cells. We constructed recombinant immunotoxins…”
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Cloning and characterization of 1116NS19.9 heavy and light chain cDNAs and expression of antibody fragments in Escherichia coli by Tonge, D W, Hennam, J F, Greene, A R, Lee, I D, Edge, M D

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Purification and Characterization of Active and Stable Recombinant Plasminogen‐Activator Inhibitor Accumulated at High Levels in Escherichia coli by Sancho, Elena, Tonge, David W., Hockney, Robert C., Booth, Nuala A.

“…Plasminogen‐activator inhibitor type 1 (PAI‐l), the primary physiological inhibitor of tissue‐type plasminogen activator, is an unusual member of the serine…”
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