Search Results - "Tong, Yuru"

Genome of Tripterygium wilfordii and identification of cytochrome P450 involved in triptolide biosynthesis by Tu, Lichan, Su, Ping, Zhang, Zhongren, Gao, Linhui, Wang, Jiadian, Hu, Tianyuan, Zhou, Jiawei, Zhang, Yifeng, Zhao, Yujun, Liu, Yuan, Song, Yadi, Tong, Yuru, Lu, Yun, Yang, Jian, Xu, Cao, Jia, Meirong, Peters, Reuben J., Huang, Luqi, Gao, Wei

“…Triptolide is a trace natural product of Tripterygium wilfordii . It has antitumor activities, particularly against pancreatic cancer cells. Identification of…”
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Morphology, rheology property, and crystallization behavior of PLLA/OMMT nanocomposites prepared by an innovative eccentric rotor extruder by Wu, Ting, Tong, Yuru, Qiu, Feng, Yuan, Ding, Zhang, Guizhen, Qu, Jinping

“…An innovative eccentric rotor extruder, which can generate continuous elongation flow, was used to fabricate the poly(L‐lactide) (PLLA)/organo‐modified…”
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Tandemly duplicated CYP82Ds catalyze 14-hydroxylation in triptolide biosynthesis and precursor production in Saccharomyces cerevisiae by Zhang, Yifeng, Gao, Jie, Ma, Lin, Tu, Lichan, Hu, Tianyuan, Wu, Xiaoyi, Su, Ping, Zhao, Yujun, Liu, Yuan, Li, Dan, Zhou, Jiawei, Yin, Yan, Tong, Yuru, Zhao, Huan, Lu, Yun, Wang, Jiadian, Gao, Wei, Huang, Luqi

“…Triptolide is a valuable multipotent antitumor diterpenoid in Tripterygium wilfordii , and its C-14 hydroxyl group is often selected for modification to…”
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Molecular Cloning and Characterization of DXS and DXR Genes in the Terpenoid Biosynthetic Pathway of Tripterygium wilfordii by Tong, Yuru, Su, Ping, Zhao, Yujun, Zhang, Meng, Wang, Xiujuan, Liu, Yujia, Zhang, Xianan, Gao, Wei, Huang, Luqi

“…1-Deoxy-d-xylulose-5-phosphate synthase (DXS) and 1-deoxy-d-xylulose-5-phosphate reductoisomerase (DXR) genes are the key enzyme genes of terpenoid…”
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The chromosome-level reference genome assembly for Panax notoginseng and insights into ginsenoside biosynthesis by Jiang, Zhouqian, Tu, Lichan, Yang, Weifei, Zhang, Yifeng, Hu, Tianyuan, Ma, Baowei, Lu, Yun, Cui, Xiuming, Gao, Jie, Wu, Xiaoyi, Tong, Yuru, Zhou, Jiawei, Song, Yadi, Liu, Yuan, Liu, Nan, Huang, Luqi, Gao, Wei

“…Panax notoginseng, a perennial herb of the genus Panax in the family Araliaceae, has played an important role in clinical treatment in China for thousands of…”
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Overexpression of TwSQS, TwSE, and TwOSC Regulates Celastrol Accumulation in Cambial Meristematic Cells and Dedifferentiated Cells by Song, Yadi, Zhou, Jiawei, Zhang, Yifeng, Zhao, Yujun, Wang, Xiujuan, Hu, Tianyuan, Tong, Yuru, Huang, Luqi, Gao, Wei

“…Squalene synthase (SQS), squalene epoxidase (SE), and oxidosqualene cyclase (OSC) are encoding enzymes in downstream biosynthetic pathway of triterpenoid in…”
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Structural and functional investigations of syn-copalyl diphosphate synthase from Oryza sativa by Ma, Xiaoli, Xu, Haifeng, Tong, Yuru, Luo, Yunfeng, Dong, Qinghua, Jiang, Tao

“…The large superfamily of labdane-related diterpenoids is defined by the cyclization of linear geranylgeranyl pyrophosphate (GGPP), catalyzed by copalyl…”
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Author Correction: Genome of Tripterygium wilfordii and identification of cytochrome P450 involved in triptolide biosynthesis by Tu, Lichan, Su, Ping, Zhang, Zhongren, Gao, Linhui, Wang, Jiadian, Hu, Tianyuan, Zhou, Jiawei, Zhang, Yifeng, Zhao, Yujun, Liu, Yuan, Song, Yadi, Tong, Yuru, Lu, Yun, Yang, Jian, Xu, Cao, Jia, Meirong, Peters, Reuben J., Huang, Luqi, Gao, Wei

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Probing the Single Key Amino Acid Responsible for the Novel Catalytic Function of ent -Kaurene Oxidase Supported by NADPH-Cytochrome P450 Reductases in Tripterygium wilfordii by Su, Ping, Guan, Hongyu, Zhang, Yifeng, Wang, Xing, Gao, Linhui, Zhao, Yujun, Hu, Tianyuan, Zhou, Jiawei, Ma, Baowei, Tu, Lichan, Tong, Yuru, Huang, Luqi, Gao, Wei

“…produces not only -kaurene, which is an intermediate of gibberellin (GA) biosynthesis in flowering plants, but also 16α-hydroxy- -kaurane, whose physiological…”
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Biogenic Synthesis and Spatial Distribution of Endogenous Phytohormones and Ginsenosides Provide Insights on Their Intrinsic Relevance in Panax ginseng by Chen, Kang, Liu, Juan, Ji, Ruifeng, Chen, Tong, Zhou, Xiuteng, Yang, Jian, Tong, Yuru, Jiang, Chao, Zhou, Junhui, Zhao, Yuyang, Jin, Yan, Yuan, Yuan, Huang, Luqi

“…Ginseng, the root and rhizome of C. A. Mey., is a well-known and valuable traditional Chinese medicine. The pharmacological activities of ginseng are mainly…”
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Molecular cloning and functional identification of a cDNA encoding 4-hydroxy-3-methylbut-2-enyl diphosphate reductase from Tripterygium wilfordii by Cheng, Qiqing, Tong, Yuru, Wang, Zihao, Su, Ping, Gao, Wei, Huang, Luqi

“…The 4-hydroxy-3-methylbut-2-enyl diphosphate reductase(HDR) is the last step key enzyme of the methylerythritol phosphate(MEP) pathway,synthesizing isopentenyl…”
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Mechanistic analysis for the origin of diverse diterpenes in Tripterygium wilfordii by Tu, Lichan, Cai, Xinbo, Zhang, Yifeng, Tong, Yuru, Wang, Jian, Su, Ping, Lu, Yun, Hu, Tianyuan, Luo, Yunfeng, Wu, Xiaoyi, Li, Dan, Huang, Luqi, Gao, Wei

“…Tripterygium wilfordii is a valuable medicinal plant rich in biologically active diterpenoids, but there are few studies on the origins of these diterpenoids…”
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Molecular cloning and functional identification of sterol C24-methyltransferase gene from Tripterygium wilfordii by Guan, Hongyu, Zhao, Yujun, Su, Ping, Tong, Yuru, Liu, Yujia, Hu, Tianyuan, Zhang, Yifeng, Zhang, Xianan, Li, Jia, Wu, Xiaoyi, Huang, Luqi, Gao, Wei

“…Sterol C24-methyltransferase(SMT) plays multiple important roles in plant growth and development. SMT1, which belongs to the family of transferases and…”
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Investigating the Catalytic Activity of Glycosyltransferase on Quercetin from Tripterygium wilfordii by Gao, Jie, Ma, Baowei, Lu, Yun, Zhang, Yifeng, Tong, Yuru, Guo, Siyuan, Gao, Wei, Huang, Luqi

“…Flavonoid glycosides have shown many pharmacological activities in clinical studies. However, the main way to obtain flavonoid glycosides is to extract and…”
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Biosynthesis of paclitaxel using synthetic biology by Tong, Yuru, Luo, Yunfeng F, Gao, Wei

“…Paclitaxel is a tricyclic diterpenoid first isolated from the bark of Taxus brevifolia . It is notably one of the most effective natural anticancer drugs…”
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Engineering chimeric diterpene synthases and isoprenoid biosynthetic pathways enables high-level production of miltiradiene in yeast by Hu, Tianyuan, Zhou, Jiawei, Tong, Yuru, Su, Ping, Li, Xinlin, Liu, Yuan, Liu, Nan, Wu, Xiaoyi, Zhang, Yifeng, Wang, Jiadian, Gao, Linhui, Tu, Lichan, Lu, Yun, Jiang, Zhouqian, Zhou, Yongjin J., Gao, Wei, Huang, Luqi

“…Miltiradiene is a key intermediate in the biosynthesis of many important natural diterpene compounds with significant pharmacological activity, including…”
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Structural and mechanistic insights into the precise product synthesis by a bifunctional miltiradiene synthase by Tong, Yuru, Ma, Xiaoli, Hu, Tianyuan, Chen, Kang, Cui, Guanghong, Su, Ping, Xu, Haifeng, Gao, Wei, Jiang, Tao, Huang, Luqi

“…Summary Selaginella moellendorffii miltiradiene synthase (SmMDS) is a unique bifunctional diterpene synthase (diTPS) that catalyses the successive cyclization…”
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Identification and functional characterization of diterpene synthases for triptolide biosynthesis from Tripterygium wilfordii by Su, Ping, Guan, Hongyu, Zhao, Yujun, Tong, Yuru, Xu, Meimei, Zhang, Yifeng, Hu, Tianyuan, Yang, Jian, Cheng, Qiqing, Gao, Linhui, Liu, Yujia, Zhou, Jiawei, Peters, Reuben J., Huang, Luqi, Gao, Wei

“…Summary Tripterygium wilfordii, which has long been used as a medicinal plant, exhibits impressive and effective anti‐inflammatory, immunosuppressive and…”
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Probing the functions of friedelane‐type triterpene cyclases from four celastrol‐producing plants by Lu, Yun, Luo, Yunfeng, Zhou, Jiawei, Hu, Tianyuan, Tu, Lichan, Tong, Yuru, Su, Ping, Liu, Yuan, Wang, Jiadian, Jiang, Zhouqian, Wu, Xiaoyi, Chen, Xiaochao, Huang, Luqi, Gao, Wei

“…SUMMARY Triterpenes are among the most diverse plant natural products, and their diversity is closely related to various triterpene skeletons catalyzed by…”
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The expression of TwDXS in the MEP pathway specifically affects the accumulation of triptolide by Zhang, Yifeng, Zhao, Yujun, Wang, Jiadian, Hu, Tianyuan, Tong, Yuru, Zhou, Jiawei, Gao, Jie, Huang, Luqi, Gao, Wei

“…1‐Deoxy‐d‐xylulose‐5‐phosphate synthase (DXS) is the first enzyme in the plant 2‐C‐methyl‐d‐erythritol 4‐phosphate (MEP) pathway of terpenoid synthesis. TwDXS…”
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