Search Results - "Tong, Yongliang"

Different Immunoregulation Roles of Activin A Compared With TGF-β by Li, Fanglin, Long, Yiru, Yu, Xiaolu, Tong, Yongliang, Gong, Likun

“…Activin A, a critical member of the transforming growth factor-β (TGF-β) superfamily, is a pluripotent factor involved in allergies, autoimmune diseases,…”
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Noncanonical PD-1/PD-L1 Axis in Relation to the Efficacy of Anti-PD Therapy by Long, Yiru, Yu, Xiaolu, Chen, Runqiu, Tong, Yongliang, Gong, Likun

“…With programmed death 1/ligand 1 (PD-1/PD-L1) as the cornerstone, anti-PD antibodies have pioneered revolutionary immunotherapies for malignancies. But most…”
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A Natural Compound Containing a Disaccharide Structure of Glucose and Rhamnose Identified as Potential N-Glycanase 1 (NGLY1) Inhibitors by Liu, Ruijie, Gu, Jingjing, Ye, Yilin, Zhang, Yuxin, Zhang, Shaoxing, Lin, Qiange, Yuan, Shuying, Chen, Yanwen, Lu, Xinrong, Tong, Yongliang, Lv, Shaoxian, Chen, Li, Sun, Guiqin

“…N-glycanase 1 (NGLY1) is an essential enzyme involved in the deglycosylation of misfolded glycoproteins through the endoplasmic reticulum (ER)-associated…”
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PD-L1/TLR7 dual-targeting nanobody-drug conjugate mediates potent tumor regression via elevating tumor immunogenicity in a host-expressed PD-L1 bias-dependent way by Yu, Xiaolu, Long, Yiru, Chen, Binfan, Tong, Yongliang, Shan, Mengwen, Jia, Xiaomin, Hu, Chao, Liu, Meng, Zhou, Ji, Tang, Feng, Lu, Henglei, Chen, Runqiu, Xu, Pan, Huang, Wei, Ren, Jin, Wan, Yakun, Sun, Jianhua, Li, Jia, Jin, Guangyi, Gong, Likun

“…BackgroundVarious tumors are insensitive to immune checkpoint blockade (ICB) therapy. Toll-like receptors (TLRs) establish the link between innate and adaptive…”
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Enzymatic Activity Analysis and Catalytic Essential Residues Identification of Brucella abortus Malate Dehydrogenase by Yu, Shengqing, Ding, Chan, Wang, Shaohui, Sun, Xiaoqing, Zhang, Yuxi, Tian, Mingxing, Tong, Yongliang, Han, Xiangan, Qiu, Xusheng

“…Malate dehydrogenase (MDH) plays important metabolic roles in bacteria. In this study, the recombinant MDH protein (His-MDH) of Brucella abortus was purified…”
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Identification and characterization of emGalaseE, a β-1,4 galactosidase from Elizabethkingia meningoseptica, and its application on living cell surface by Tong, Yongliang, Lu, Xinrong, Shen, Danfeng, Rao, Lin, Zou, Lin, Lyu, Shaoxian, Hou, Linlin, Sun, Guiqin, Chen, Li

“…The biological function of terminal galactose on glycoprotein is an open field of research. Although progress had being made on enzymes that can remove the…”
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Identification and characterization of an α-1,3 mannosidase from Elizabethkingia meningoseptica and its potential attenuation impact on allergy associated with cross-reactive carbohydrate determinant by Shen, Danfeng, Lu, Xinrong, Li, Wenjie, Zou, Lin, Tong, Yongliang, Wang, Lei, Rao, Lin, Zhang, Yuxin, Hou, Linlin, Sun, Guiqin, Chen, Li

“…Core α-1,3 mannose is structurally near the core xylose and core fucose on core pentasaccharide from plant and insect glycoproteins. Mannosidase is a useful…”
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New laboratory evidence for the association between endothelial dysfunction and COVID‐19 disease progression by Liu, Nan, Long, Hui, Sun, Jianhua, Li, Huan, He, Yunting, Wang, Qiang, Pan, Kai, Tong, Yongliang, Wang, Bingshun, Wu, Qingming, Gong, Likun

“…There is growing evidence that angiotensin‐converting enzyme 2 is highly expressed on endothelial cells, endothelial dysfunction plays a critical role in…”
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Carbohydrate Strengthens the Immunotherapeutic Effect of Small-Molecule PD-L1 Inhibitors by Dong, Qian, Tong, Mengya, Yu, Xiaolu, Wang, Lei, Ao, Jiwei, Guan, Dongliang, Tang, Yubo, Liu, Junjie, Long, Li, Tong, Yongliang, Fang, Shanhua, Zhou, Hu, Huang, Yongzhuo, Gong, Likun, Lou, Liguang, Huang, Wei

“…PD-1/PD-L1 checkpoint blockade has demonstrated great success in cancer immunotherapy. Small-molecule PD-L1 inhibitors also attract significant research…”
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Suppression of Tumor or Host Intrinsic CMTM6 Drives Antitumor Cytotoxicity in a PD-L1-Independent Manner by Long, Yiru, Chen, Runqiu, Yu, Xiaolu, Tong, Yongliang, Peng, Xionghua, Li, Fanglin, Hu, Chao, Sun, Jianhua, Gong, Likun

“…CKLF-like MARVEL transmembrane domain-containing protein 6 (CMTM6) is known to be a regulator of membranal programmed death ligand 1 (PD-L1) stability and a…”
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Development of a bridging ELISA for detection of antibodies against ZV0203 in cynomolgus monkey serum by Liu, Tingting, Tong, Yongliang, Gao, Jinli, Fang, Wenjing, Wu, Junliang, Peng, Xionghua, Fan, Xiaotian, Chen, Xiaoqiang, Sun, Jianhua, Cao, Sheldon, Li, Zhaohui, Gong, Likun, Qin, Qiuping, Ju, Dianwen

“…Immunogenicity has been a major concern in the safety evaluation of therapeutic proteins. The assessment of the unwanted immunogenicity of the therapeutic…”
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Characterization of the immunogenicity and pathogenicity of malate dehydrogenase in Brucella abortus by Han, Xiangan, Tong, Yongliang, Tian, Mingxing, Sun, Xiaoqing, Wang, Shaohui, Ding, Chan, Yu, Shengqing

“…Brucella abortus is a gram-negative, facultative intracellular pathogen that causes brucellosis, a chronic zoonotic disease resulting in abortion in pregnant…”
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Characterization and Molecular Mechanism of Aminoglycoside-6-Adenyl Transferase Associated with Aminoglycoside Resistance from Elizabethkingia meningoseptica by Zhang, Shaoxing, Zhang, Yuxin, Liu, Ruijie, Yuan, Shuying, Chen, Yanwen, Li, Wenjie, Lu, Xinrong, Tong, Yongliang, Hou, Linlin, Chen, Li, Sun, Guiqin

“…Purpose: Elizabethkingia meningoseptica (EM) is a multi-drug-resistant bacterium of global concern for its role in nosocomial infection and is generally…”
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In vivo-induced argininosuccinate lyase plays a role in the replication of Brucella abortus in RAW264.7 cells by Han, Xiangan, Sun, Xiaoqing, Shan, Xueqing, Zhang, Min, Song, Jun, Tian, Mingxing, Fan, Guobo, Wang, Shaohui, Tong, Yongliang, Ding, Chan, Yu, Shengqing

“…Brucellosis caused by Brucella species is a zoonotic disease with a serious impact on public health and the livestock industry. To better understand the…”
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Prediction of fish body＇s passive visco-elastic properties and related muscle mechanical performance in vivo during steady swimming by ZHANG Wei YU YongLiang TONG BingGang

“…For attaining the optimized locomotory performance of swimming fishes, both the passive visco-elastic properties of the fish body and the mechanical behavior…”
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Study of blood exposure-related mental health illness among clinical nurses by Xiong, Xiaojia, Li, Min, Jiang, Yongliang, Tong, Xindeng, Peng, Yanzhong

“…Nurses are subjected to high amount of stress in the medical setting, and work-related stress often leads to mental problems. This study aims to investigate…”
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A flow control mechanism in wing flapping with stroke asymmetry during insect forward flight by Yu, Yongliang, Tong, Binggang

“…A theoretical modeling approach as well as an unsteady analytical method is used to study aerodynamic characteristics of wing flapping with asymmetric…”
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