Search Results - "Tong, Xiangming"
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Comparison of Pharmacokinetics and Bioavailability of Fixed‐Dose Combination Tablet and Monotherapy Combination of Allisartan Isoproxil and Indapamide Sustained‐Release in Healthy Chinese Volunteers
Published in Clinical pharmacology in drug development (01-02-2024)“…This study aimed to compare the pharmacokinetics and bioavailability of 2 formulations: a fixed‐dose combination tablet containing allisartan isoproxil (AI)…”
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2
Extracellular signal-regulated kinase1/2 activated by fluid shear stress promotes osteogenic differentiation of human bone marrow-derived mesenchymal stem cells through novel signaling pathways
Published in The international journal of biochemistry & cell biology (01-11-2011)“…It is a classical signaling pathway that the activation of extracellular signal-regulated kinase1/2 (ERK1/2) results in the phosphorylation of runt-related…”
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3
Different effects of intermittent and continuous fluid shear stresses on osteogenic differentiation of human mesenchymal stem cells
Published in Biomechanics and modeling in mechanobiology (01-03-2012)“…A reasonable mechanical microenvironment similar to the bone microenvironment in vivo is critical to the formation of engineering bone tissues. As fluid shear…”
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4
Homoharringtonine mediates myeloid cell apoptosis via upregulation of pro‐apoptotic bax and inducing caspase‐3‐mediated cleavage of poly(ADP‐ribose) polymerase (PARP)
Published in American journal of hematology (01-07-2004)“…Homoharringtonine (HHT) is a plant alkaloid with antileukemia activity that is currently being used for treatment of acute, chronic leukemias and MDS. In this…”
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5
C21 steroid-enriched fraction refined from Marsdenia tenacissima inhibits hepatocellular carcinoma through the coordination of Hippo-Yap and PTEN-PI3K/AKT signaling pathways
Published in Oncotarget (15-12-2017)“…extraction (MTE), a traditional herbal medicine, has exhibited anti-tumor effects on a variety of cancers. However, its effectiveness and the mechanism of…”
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6
The interaction between β1 integrins and ERK1/2 in osteogenic differentiation of human mesenchymal stem cells under fluid shear stress modelled by a perfusion system
Published in Journal of tissue engineering and regenerative medicine (01-02-2014)“…Fluid shear stress (FSS) is an important biomechanical factor regulating the osteogenic differentiation of human mesenchymal stem cells (hMSCs) and is…”
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Effects of BMP-2 and FGF2 on the Osteogenesis of Bone Marrow-Derived Mesenchymal Stem Cells in Hindlimb-Unloaded Rats
Published in Cell biochemistry and biophysics (01-11-2014)“…Hindlimb unloading, as a simulation of microgravity, decreases the osteogenic potential of mesenchymal stem cells (MSCs) from hindlimb femur of rat. We…”
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Pharmacokinetics and Drug–Drug Interaction of Allisartan Isoproxil and Indapamide Sustained‐Release Formulation
Published in Clinical pharmacology in drug development (01-11-2023)“…Allisartan isoproxil (AI) is an angiotensin II type 1 receptor blocker and be converted into the active substance EXP3174 in vivo. We evaluated the drug–drug…”
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9
New Approaches for Treatment of Advanced Extranodal NK/T-Cell Lymphoma
Published in Cancer management and research (01-01-2022)“…Extranodal NK/T cell lymphoma (ENKL) is a rare subtype of lymphoma that shows a poor clinical outcome. The most common sites are the nasal cavity, nasopharynx,…”
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10
Exchange protein activated by cyclic adenosine monophosphate regulates the switch between adipogenesis and osteogenesis of human mesenchymal stem cells through increasing the activation of phosphatidylinositol 3-kinase
Published in The international journal of biochemistry & cell biology (01-07-2012)“…Epac, exchange protein activated by cyclic adenosine monophosphate (cAMP), could regulate the trans-differentiation between adipogenesis and osteogenesis of…”
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11
Studies on culture and osteogenic induction of human mesenchymal stem cells under CO2-independent conditions
Published in Astrobiology (01-04-2013)“…Human mesenchymal stem cells (hMSCs) are one of the important factors that regulate bone anabolism. Osteoporosis resulting from microgravity during spaceflight…”
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The interaction between β 1 integrins and ERK1/2 in osteogenic differentiation of human mesenchymal stem cells under fluid shear stress modelled by a perfusion system: β 1 integrins ERK1/2 in osteogenic differentiation of hMSCs under FSS
Published in Journal of tissue engineering and regenerative medicine (01-02-2014)Get full text
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13
The interaction between [beta]1 integrins and ERK1/2 in osteogenic differentiation of human mesenchymal stem cells under fluid shear stress modelled by a perfusion system
Published in Journal of tissue engineering and regenerative medicine (01-02-2014)“…Fluid shear stress (FSS) is an important biomechanical factor regulating the osteogenic differentiation of human mesenchymal stem cells (hMSCs) and is…”
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14
Cloning and expression of retinoic acid-induced gene-I and its effect on hepatitis C virus replication
Published in Laboratory medicine (01-03-2014)“…To explore the influence of the retinoic acid indicible gene-I (RIG-I) on hepatitis C virus (HCV) replication and the molecular mechanism of action of RIG-I…”
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15
Leukemia: Derived heat shock protein gp96-peptide complex contribution to T cell and dendritic cell activation
Published in African journal of biotechnology (27-06-2011)“…The molecular chaperone, heat shock protein gp96 (HSP-gp96), has been shown to have roles in the synthesis, processing and transport of tumor antigens…”
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A patient of extramedullary cutaneous and gingival plasmacytomas
Published in European journal of haematology (01-08-2005)Get full text
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