Search Results - "Tong, Qiang"
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COVID-19: a recommendation to examine the effect of hydroxychloroquine in preventing infection and progression
Published in Journal of antimicrobial chemotherapy (01-07-2020)“…Abstract A novel coronavirus disease (COVID-19), caused by infection with SARS-CoV-2, has swept across 31 provinces in China and over 40 countries worldwide…”
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SIRT3 promotes lipophagy and chaperon-mediated autophagy to protect hepatocytes against lipotoxicity
Published in Cell death and differentiation (01-01-2020)“…Lipophagy is a lysosomal lipolytic pathway that complements the actions of cytosolic neutral lipases. Chaperon-mediated autophagy (CMA) triggers lipid droplets…”
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SIRT3 Acts as a Positive Autophagy Regulator to Promote Lipid Mobilization in Adipocytes via Activating AMPK
Published in International journal of molecular sciences (07-01-2020)“…Obesity is increasing at an alarming rate worldwide, which is characterized by the excessive accumulation of triglycerides in adipocytes. Emerging evidence has…”
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From pathogenesis to treatment: the impact of bacteria on cancer
Published in Frontiers in microbiology (18-09-2024)“…The intricate relationship between cancer and bacteria has garnered increasing attention in recent years. While traditional cancer research has primarily…”
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Mapping Object-Oriented Database Models Into RDF(S)
Published in IEEE access (01-01-2018)“…Resource description framework RDF and RDF schema (collectively called RDF(S)) are the normative languages to describe the Web resource information. How to…”
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SIRT3 protects hepatocytes from oxidative injury by enhancing ROS scavenging and mitochondrial integrity
Published in Cell death & disease (26-10-2017)“…Evidences of oxidative stress and mitochondrial dysfunction have been recognized in most of clinical and experimental liver diseases. SIRT3, a member of NAD +…”
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Development of gestational diabetes mellitus in women with periodontitis in early pregnancy: A population‐based clinical study
Published in Journal of clinical periodontology (01-02-2022)“…Aim This study aimed to determine whether periodontitis in early pregnancy and periodontal therapy during gestation affect the incidence of gestational…”
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Co-delivery of doxorubicin and SATB1 shRNA by thermosensitive magnetic cationic liposomes for gastric cancer therapy
Published in PloS one (27-03-2014)“…In previous a study, we had developed a novel thermosensitive magnetic delivery system based on liposomes. This study aimed to evaluate the efficiency of this…”
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Baicalin enhances the efficacy of 5-Fluorouracil in gastric cancer by promoting ROS-mediated ferroptosis
Published in Biomedicine & pharmacotherapy (01-08-2023)“…5-Fluorouracil (5-Fu) is one of the most commonly used chemotherapy drugs for gastric cancer (GC). But the increase of drug resistance makes the prognosis of…”
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Incidence risk of PD-1/PD-L1–related pneumonia and diarrhea in non-small cell lung cancer (NSCLC) patients: a systematic review and meta-analysis of randomized controlled trials
Published in European journal of clinical pharmacology (01-08-2021)“…Background Programmed cell death-1 (PD-1) and programmed cell death ligand-1(PD-L1) inhibitor therapy have been approved for the treatment of many cancers,…”
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NLRP3 Inflammasome Inhibition Prevents α-Synuclein Pathology by Relieving Autophagy Dysfunction in Chronic MPTP–Treated NLRP3 Knockout Mice
Published in Molecular neurobiology (01-04-2021)“…Recent researches showed that nucleotide-binding domain and leucine-rich repeat protein 3 (NLRP3) inflammasome inhibition exerted dopaminergic neuroprotection…”
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Role of epithelial-mesenchymal transition in gastric cancer initiation and progression
Published in World journal of gastroenterology : WJG (14-05-2014)“…Gastric cancer is one of the most common malignant tumors worldwide.Due to its intricate initiation and progression mechanisms,early detection and effective…”
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13
Regulation of Succinate Dehydrogenase Activity by SIRT3 in Mammalian Mitochondria
Published in Biochemistry (Easton) (19-01-2010)“…A member of the sirtuin family of NAD+-dependent deacetylases, SIRT3, is identified as one of the major mitochondrial deacetylases located in mammalian…”
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Berberine remodels adipose tissue to attenuate metabolic disorders by activating sirtuin 3
Published in Acta pharmacologica Sinica (01-05-2022)“…Adipose tissue remodelling is considered a critical pathophysiological hallmark of obesity and related metabolic diseases. Berberine (BBR), a natural…”
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Identification of peanut skin components for treating hepatocellular carcinoma via network pharmacology and in vitro experiments
Published in Chemical biology & drug design (01-01-2024)“…Peanut skin (PS) contains various flavonoids and phenols that have antitumor and antioxidant effects. However, no research has been conducted on PS and…”
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NRF2 activation by antioxidant antidiabetic agents accelerates tumor metastasis
Published in Science translational medicine (13-04-2016)“…Cancer is a common comorbidity of diabetic patients; however, little is known about the effects that antidiabetic drugs have on tumors. We discovered that…”
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Sirtuin-3 (SIRT3) Protein Attenuates Doxorubicin-induced Oxidative Stress and Improves Mitochondrial Respiration in H9c2 Cardiomyocytes
Published in The Journal of biological chemistry (24-04-2015)“…Doxorubicin (DOX) is a chemotherapeutic agent effective in the treatment of many cancers. However, cardiac dysfunction caused by DOX limits its clinical use…”
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Predictive value of miR-636 in patients with acute myocardial infarction undergoing percutaneous coronary intervention and its bioinformatics analysis
Published in Journal of cardiothoracic surgery (01-10-2024)“…MicroRNAs (miRNAs) play an important role in the pathogenesis of cardiovascular diseases such as acute myocardial infarction (AMI). Percutaneous coronary…”
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Efficacy of interleukin-17 inhibitors on radiographic progression in psoriatic arthritis: A systematic review and meta-analysis
Published in Chinese medical journal (20-02-2024)“…The therapeutic effects of IL-17 inhibitors on structural damage were not consistent over multiple trials. [...]a systematic review and meta-analysis of the…”
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Orchestrated biomechanical, structural, and biochemical stimuli for engineering anisotropic meniscus
Published in Science translational medicine (10-04-2019)“…Reconstruction of the anisotropic structure and proper function of the knee meniscus remains an important challenge to overcome, because the complexity of the…”
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