Search Results - "Tong, Luqing"

Notch1 signaling pathway promotes invasion, self-renewal and growth of glioma initiating cells via modulating chemokine system CXCL12/CXCR4 by Yi, Li, Zhou, Xingchen, Li, Tao, Liu, Peidong, Hai, Long, Tong, Luqing, Ma, Haiwen, Tao, Zhennan, Xie, Yang, Zhang, Chen, Yu, Shengping, Yang, Xuejun

“…Glioma initiating cells (GICs), also known as glioma stem cells (GSCs), play an important role in the progression and recurrence of glioblastoma multiforme…”
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Proteomics shows that brain metastases of lung adenocarcinoma overexpress ribosomal proteins in response to gamma knife radiosurgery by Tong, Luqing, Ye, Ke, Chen, Qun, Wang, Xiaoxi, Hu, Chi, Xu, Qingsheng, Zhou, Lihui, Zhan, Renya, Tong, Ying

“…Gamma knife radiosurgery (GKRS) is recommended as the first-line treatment for brain metastases of lung adenocarcinoma (LUAD) in many guidelines, but its…”
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Molecular and clinical characterization of Galectin‐9 in glioma through 1,027 samples by Yuan, Feng, Ming, Haolang, Wang, Yingshuai, Yang, Yihan, Yi, Li, Li, Tao, Ma, Haiwen, Tong, Luqing, Zhang, Liang, Liu, Peidong, Li, Jiabo, Lin, Yu, Yu, Shengping, Ren, Bingcheng, Yang, Xuejun

“…In recent years, research on glioma immunotherapy have grown rapidly. However, the autoimmune‐like side effects that are caused by blocking immunological…”
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Immunological and clinicopathological characteristics of C1RL in 2120 glioma patients by Wang, Junyou, Tong, Luqing, Lin, Gaojun, Wang, Hui, Zhang, Liang, Yang, Xuejun

“…Glioma is a deadly and immunosuppressive brain tumour. Complement C1r subcomponent like (C1RL), a prognostic biomarker in several kinds of tumours, has…”
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CLEC5A expressed on myeloid cells as a M2 biomarker relates to immunosuppression and decreased survival in patients with glioma by Tong, Luqing, Li, Jiabo, Choi, John, Pant, Ayush, Xia, Yuanxuan, Jackson, Christopher, Liu, Peidong, Yi, Li, Boussouf, Elias, Lim, Michael, Yang, Xuejun

“…Glioma is the most common tumor in the central nervous system that portends a poor prognosis. Key genes negatively related to survival may provide targets for…”
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Autophagy suppresses self-renewal ability and tumorigenicity of glioma-initiating cells and promotes Notch1 degradation by Tao, Zhennan, Li, Tao, Ma, Haiwen, Yang, Yihan, Zhang, Chen, Hai, Long, Liu, Peidong, Yuan, Feng, Li, Jiabo, Yi, Li, Tong, Luqing, Wang, Yingshuai, Xie, Yang, Ming, Haolang, Yu, Shengping, Yang, Xuejun

“…Autophagy is a vital process that involves degradation of long-lived proteins and dysfunctional organelles and contributes to cellular metabolism…”
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Combination checkpoint therapy with anti-PD-1 and anti-BTLA results in a synergistic therapeutic effect against murine glioblastoma by Choi, John, Medikonda, Ravi, Saleh, Laura, Kim, Timothy, Pant, Ayush, Srivastava, Siddhartha, Kim, Young-Hoon, Jackson, Christina, Tong, Luqing, Routkevitch, Denis, Jackson, Christopher, Mathios, Dimitrios, Zhao, Tianna, Cho, Hyerim, Brem, Henry, Lim, Michael

“…Clinical trials involving anti-programmed cell death protein-1 (anti-PD-1) failed to demonstrate improved overall survival in glioblastoma (GBM) patients. This…”
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Sustained localized delivery of immunotherapy to lymph nodes reverses immunosuppression and increases long-term survival in murine glioblastoma by Choi, John, Pant, Ayush, Medikonda, Ravi, Kim, Young-Hoon, Routkevitch, Denis, Saleh, Laura, Tong, Luqing, Chan, Hok Yee, Nedrow, Jessie, Jackson, Christopher, Jackson, Christina, Lim, Michael

“…Despite the advent of immunotherapy as a promising therapeutic, glioblastoma (GBM) remains resistant to using checkpoint blockade due to its highly…”
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Jagged1 is Clinically Prognostic and Promotes Invasion of Glioma-Initiating Cells by Activating NF-κB(p65) Signaling by Hai, Long, Liu, Peidong, Yu, Shengping, Yi, Li, Tao, Zhennan, Zhang, Chen, Abeysekera, Iruni Roshanie, Li, Tao, Tong, Luqing, Ma, Haiwen, Liu, Bo, Xie, Yang, Zhou, Xingchen, Lin, Yu, Zhu, Meng, Zhang, Kai, Ren, Bingcheng, Ming, Haolang, Huang, Yubao, Yang, Xuejun 

“…Background/Aims: Jagged1 is the ligands of the Notch signaling and has been shown to promote glioma-initiating cells (GICs) in glioblastoma. The role of…”
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A contemporary molecular view of diffuse gliomas with implications for diagnosis by Li, Jiabo, Wang, Xuya, Tong, Luqing, Yang, Xuejun, Brat, Daniel

“…Diffuse gliomas are a family of neoplastic diseases characterized by widespread infiltration of central nervous system structures by tumor cells displaying…”
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IKBKE, a prognostic factor preferentially expressed in mesenchymal glioblastoma, modulates tumoral immunosuppression through the STAT3/PD‐L1 pathway by Yi, Li, Guo, Gaochao, Li, Jiabo, Fan, Xiaoguang, Li, Tao, Tong, Luqing, Liu, Peidong, Wang, Xuya, Yuan, Feng, Yu, Shengping, Huang, Qiang, Yang, Xuejun

“…Inhibitor of nuclear factor kappa‐B kinase subunit epsilon (IKBKE) plays critical roles in the proliferation, invasion, and epithelial‐mesenchymal transition…”
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ACT001 reduces the expression of PD-L1 by inhibiting the phosphorylation of STAT3 in glioblastoma by Tong, Luqing, Li, Jiabo, Li, Qiuying, Wang, Xuya, Medikonda, Ravi, Zhao, Tianna, Li, Tao, Ma, Haiwen, Yi, Li, Liu, Peidong, Xie, Yang, Choi, John, Yu, Shengping, Lin, Yu, Dong, Jun, Huang, Qiang, Jin, Xun, Lim, Michael, Yang, Xuejun

“…ACT001, which is derived from an ancient anti-inflammatory drug, has been shown to cross the blood-brain barrier in preclinical studies and has demonstrated…”
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1241 Sustained Localized Delivery of Anti-PD-1 to Tumor Draining Lymph Nodes Increases Survival and Reverses Immunosuppression in Murine Glioblastoma Models by Choi, John, Pant, Ayush, Medikonda, Ravi, Kim, Young-Hoon, Routkevitch, Denis, Saleh, Laura, Tong, Luqing, Chan, Hok Yee, Nedrow, Jessie, Jackson, Christopher Mitchell, Jackson, Christina, Lim, Michael

“…INTRODUCTION: Despite the advent of immunotherapy as a promising therapeutic, glioblastoma (GBM) remains resistant to using checkpoint blockade against…”
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TMIC-14. CLEC5A REGULATES TAM POLARIZATION, TME IMMUNOSUPPRESSION AND DISEASE PROGRESSION IN GLIOBLASTOMA by Li, Jiabo, Wang, Xuya, Tong, Luqing, Markwell, Steven, Shih, Ling-Kai, Olson, Cheryl, Carneiro-Lobo, Tatiana, Yang, Xunjun, Brat, Daniel

“…Abstract Glioblastoma, IDH-wildtype (WHO grade 4) is the most common primary malignant brain tumor of adults and is characterized by an immunosuppressive tumor…”
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Prognostic value of carcinoembryonic antigen on outcome in patients with coronavirus disease 2019 by Yu, Jing, Yang, Zhifeng, Zhou, Xia, Wu, Dongde, Chen, Jian, Zhang, Ling, Tong, Luqing, Nie, Lei

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TMIC-21. THE ROLE OF CLEC5A ON M2-LIKE TUMOR-ASSOCIATED MACROPHAGES POLARIZATION AND DISEASE PROGRESSION IN GLIOBLASTOMA by Li, Jiabo, Wang, Xuya, Markwell, Steven, Carneiro-Lobo, Tatiana, Olson, Cheryl, Shih, Ling-Kai, Tong, Luqing, Yang, Xuejun, Brat, Daniel

“…Abstract Glioblastoma, IDH-wildtype (GBM, WHO grade 4) is the most common primary intracranial malignant tumor of adults and is characterized by an…”
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NKCC1 promotes EMT‐like process in GBM via RhoA and Rac1 signaling pathways by Ma, Haiwen, Li, Tao, Tao, Zhennan, Hai, Long, Tong, Luqing, Yi, Li, Abeysekera, Iruni R., Liu, Peidong, Xie, Yang, Li, Jiabo, Yuan, Feng, Zhang, Chen, Yang, Yihan, Ming, Haolang, Yu, Shengping, Yang, Xuejun

“…Glioblastoma is the most common and lethal primary intracranial tumor. As the key regulator of tumor cell volume, sodium‐potassium‐chloride cotransporter 1…”
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TMEM158 promotes the proliferation and migration of glioma cells via STAT3 signaling in glioblastomas by Li, Jiabo, Wang, Xuya, Chen, Lulu, Zhang, Jinhao, Zhang, Yiming, Ren, Xiao, Sun, Jinzhang, Fan, Xiaoguang, Fan, Jikang, Li, Tao, Tong, Luqing, Yi, Li, Chen, Lei, Liu, Jie, Shang, Guanjie, Ren, Xiude, Zhang, Hao, Yu, Shengping, Ming, Haolang, Huang, Qiang, Dong, Jun, Zhang, Chen, Yang, Xuejun

“…Glioblastoma is the most common primary intracranial malignant tumor in adults and has high morbidity and high mortality. TMEM158 has been reported to promote…”
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Synergy between glutamate modulation and anti-programmed cell death protein 1 immunotherapy for glioblastoma by Medikonda, Ravi, Choi, John, Pant, Ayush, Saleh, Laura, Routkevitch, Denis, Tong, Luqing, Belcaid, Zineb, Kim, Young Hoon, Jackson, Christopher M, Jackson, Christina, Mathios, Dimitrios, Xia, Yuanxuan, Shah, Pavan P, Patel, Kisha, Kim, Timothy, Srivastava, Siddhartha, Huq, Sakibul, Ehresman, Jeff, Pennington, Zach, Tyler, Betty, Brem, Henry, Lim, Michael

“…Immune checkpoint inhibitors such as anti-programmed cell death protein 1 (anti-PD-1) have shown promise for the treatment of cancers such as melanoma, but…”
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Glutamate Modulation Synergizes With Anti-PD-1 Immunotherapy in Glioblastoma by Medikonda, Ravi, Choi, John, Pant, Ayush, Saleh, Laura, Routkevitch, Denis, Tong, Luqing, Belcaid, Zineb, Kim, Young H, Jackson, Christopher M, Mathios, Dimitrios, Shah, Pavan P, Lim, Michael

“…INTRODUCTION Immune checkpoint inhibitors such as anti-PD-1 have shown promise in other cancers such as melanoma, but results in GBM have been disappointing…”
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