Search Results - "Tong, Jing‐Shan"
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P2X7R promotes angiogenesis and tumour‐associated macrophage recruitment by regulating the NF‐κB signalling pathway in colorectal cancer cells
Published in Journal of cellular and molecular medicine (01-09-2020)“…Overexpression of P2X7R has been observed in several tumours and is related to cancer advancement and metastasis. However, the role of P2X7R in colorectal…”
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miR‐126 reduces trastuzumab resistance by targeting PIK3R2 and regulating AKT/mTOR pathway in breast cancer cells
Published in Journal of cellular and molecular medicine (01-07-2020)“…MicroRNAs (miRNAs) have been found to play a key role in drug resistance. In the current study, we aimed to explore the potential role of miR‐126 in…”
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The miR-30a-5p/CLCF1 axis regulates sorafenib resistance and aerobic glycolysis in hepatocellular carcinoma
Published in Cell death & disease (23-10-2020)“…HCC (hepatocellular carcinoma) is a major health threat for the Chinese population and has poor prognosis because of strong resistance to chemotherapy in…”
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4
Icaritin causes sustained ERK1/2 activation and induces apoptosis in human endometrial cancer cells
Published in PloS one (08-03-2011)“…Icaritin, a compound from Epimedium Genus, has selective estrogen receptor (ER) modulating activities, and possess anti-tumor activity. Here, we examined…”
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5
ER-α36, a novel variant of ER-α, mediates estrogen-stimulated proliferation of endometrial carcinoma cells via the PKCδ/ERK pathway
Published in PloS one (04-11-2010)“…Recently, a variant of ER-α, ER-α36 was identified and cloned. ER-α36 lacks intrinsic transcription activity and mainly mediates non-genomic estrogen…”
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The SUMO pathway functions in mouse oocyte maturation
Published in Cell cycle (Georgetown, Tex.) (01-07-2010)“…Sumoylation is an important post-translational modification in which SUMO (small ubiquitin-related modifier) proteins are bonded covalently to their…”
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ERK3 is required for metaphase-anaphase transition in mouse oocyte meiosis
Published in PloS one (29-09-2010)“…ERK3 (extracellular signal-regulated kinase 3) is an atypical member of the mitogen-activated protein (MAP) kinase family of serine/threonine kinases. Little…”
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Short-term preservation of porcine oocytes in ambient temperature: novel approaches
Published in PloS one (07-12-2010)“…The objective of this study was to evaluate the feasibility of preserving porcine oocytes without freezing. To optimize preservation conditions, porcine…”
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MAPK-activated protein kinase 2 is required for mouse meiotic spindle assembly and kinetochore-microtubule attachment
Published in PloS one (28-06-2010)“…MAPK-activated protein kinase 2 (MK2), a direct substrate of p38 MAPK, plays key roles in multiple physiological functions in mitosis. Here, we show for the…”
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10
Inhibition of EZH2 enhances the therapeutic effect of 5-FU via PUMA upregulation in colorectal cancer
Published in Cell death & disease (12-12-2020)“…Although the survival rate of patients with cancer have increased due to the use of current chemotherapeutic agents, adverse effects of cancer therapy remain a…”
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11
Localization and function of mSpindly during mouse oocyte meiotic maturation
Published in Cell cycle (Georgetown, Tex.) (01-06-2010)“…Spindly was first identified in Drosophila; its homologues are termed SPDL-1 in Caenorhabditis elegans and Hs Spindly/hSpindly in humans. In all species,…”
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Retraction Note: Inhibition of EZH2 enhances the therapeutic effect of 5-FU via PUMA upregulation in colorectal cancer
Published in Cell death & disease (29-03-2023)Get full text
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13
JNK2 participates in spindle assembly during mouse oocyte meiotic maturation
Published in Microscopy and microanalysis (01-04-2011)“…It is well known that c-Jun N-terminal kinase (JNK) plays pivotal roles in various mitotic events, but its function in mammalian oocyte meiosis remains…”
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14
GM130, a cis-Golgi protein, regulates meiotic spindle assembly and asymmetric division in mouse oocyte
Published in Cell cycle (Georgetown, Tex.) (01-06-2011)“…GM130, a cis-Golgi protein, plays key roles in various mitotic events, but its function in mammalian oocyte meiosis remains unknown. In this study, we found…”
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RETRACTED ARTICLE: Inhibition of EZH2 enhances the therapeutic effect of 5-FU via PUMA upregulation in colorectal cancer
Published in Cell death & disease (12-12-2020)“…Although the survival rate of patients with cancer have increased due to the use of current chemotherapeutic agents, adverse effects of cancer therapy remain a…”
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16
The novel proteasome inhibitor carfilzomib activates and enhances extrinsic apoptosis involving stabilization of death receptor 5
Published in Oncotarget (10-07-2015)“…Carfilzomib (CFZ) is a second generation proteasome inhibitor approved for the treatment of patients with multiple myeloma. It induces apoptosis in human…”
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Suppression of death receptor 5 enhances cancer cell invasion and metastasis through activation of caspase-8/TRAF2-mediated signaling
Published in Oncotarget (01-12-2015)“…The role of death receptor 5 (DR5), a well-known cell surface pro-apoptotic protein, in the negative regulation of invasion and metastasis of human cancer…”
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18
DYNLT3 is required for chromosome alignment during mouse oocyte meiotic maturation
Published in Reproductive sciences (Thousand Oaks, Calif.) (01-10-2011)“…Dynein light chain, Tctex-type 3 (DYNLT3), is a member of the cytoplasmic dynein DYNLT light chain family and has been reported to have a potential role in…”
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Expression of anti-HIV envelope glycoprotein scFv in Pichia pastoris and its biologic activities analysis
Published in Xi bao yu fen zi mian yi xue za zhi (01-12-2007)“…To construct the vector and express anti-HIV-1 envelope glycoprotein single chain Fv fragment in Pichia pastoris. The target gene was digested from plasmid…”
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ER-[alpha]36, a Novel Variant of ER-[alpha], Mediates Estrogen-Stimulated Proliferation of Endometrial Carcinoma Cells via the PKC[delta]/ERK Pathway
Published in PloS one (04-11-2010)“…Background Recently, a variant of ER-[alpha], ER-[alpha]36 was identified and cloned. ER-[alpha]36 lacks intrinsic transcription activity and mainly mediates…”
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