Search Results - "Tong, Hoi Y"
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Severe Hyponatremia Is Often Drug Induced: 10‐Year Results of a Prospective Pharmacovigilance Program
Published in Clinical pharmacology and therapeutics (01-12-2019)“…We conducted a prospective evaluation of drug‐induced severe hyponatremia (adverse drug reaction (ADR)) through the Prospective Pharmacovigilance Program from…”
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A New Pharmacogenetic Algorithm to Predict the Most Appropriate Dosage of Acenocoumarol for Stable Anticoagulation in a Mixed Spanish Population
Published in PloS one (15-03-2016)“…There is a strong association between genetic polymorphisms and the acenocoumarol dosage requirements. Genotyping the polymorphisms involved in the…”
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3
Vancomycin-Induced Acute Kidney Injury Detected by a Prospective Pharmacovigilance Program From Laboratory Signals
Published in Therapeutic drug monitoring (01-06-2013)“…Retrospective studies have identified elevated vancomycin trough levels >20 mg/L as a predictor of nephrotoxicity with a high variable incidence of 12.6%-65%…”
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Hypersensitivity reactions to contrast media injections: a nested case–control study
Published in Annals of allergy, asthma, & immunology (01-10-2014)Get full text
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5
Liver Transplant in a Patient under Methylphenidate Therapy: A Case Report and Review of the Literature
Published in Case reports in pediatrics (01-01-2015)“…Background. Methylphenidate (MPH) is widely used in treating children with attention-deficit-hyperactivity disorder. Hepatotoxicity is a rare phenomenon; only…”
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Significant HLA class I type associations with aromatic antiepileptic drug (AED)-induced SJS/TEN are different from those found for the same AED-induced DRESS in the Spanish population
Published in Pharmacological research (01-01-2017)“…[Display omitted] Aromatic antiepileptic drugs (AEDs) are among the drugs most frequently involved in severe cutaneous adverse reactions (SCARs), such as…”
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Symptomatic thromboembolic events in patients treated with intravenous-immunoglobulins: Results from a retrospective cohort study
Published in Thrombosis research (01-06-2014)“…Abstract Aims To estimate the incidence and predictors of symptomatic arterial and venous thromboembolic events (TEE) from intravenous immunoglobulin (IVIg)…”
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Eosinophilic drug reactions detected by a prospective pharmacovigilance programme in a tertiary hospital
Published in British journal of clinical pharmacology (01-02-2017)“…Aim We conducted a prospective evaluation of all eosinophilic drug reactions (EDRs) through the Prospective Pharmacovigilance Program from Laboratory Signals…”
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Clinical Implementation of Pharmacogenetic Testing in a Hospital of the Spanish National Health System: Strategy and Experience Over 3 Years
Published in Clinical and translational science (01-03-2018)“…In 2014, we established a pharmacogenetics unit with the intention of facilitating the integration of pharmacogenetic testing into clinical practice. This unit…”
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Study protocol for a phase II, multicentre, prospective, non-randomised clinical trial to assess the safety and efficacy of infusing allogeneic activated and expanded natural killer cells as consolidation therapy for paediatric acute myeloblastic leukaemia
Published in BMJ open (08-01-2020)“…IntroductionAcute myeloblastic leukaemia (AML) constitutes the second most common haematological malignancy in the paediatric population. Current treatment…”
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Hepatotoxicity induced by acute and chronic paracetamol overdose in adults. Where do we stand?
Published in Regulatory toxicology and pharmacology (01-07-2015)“…•We estimated the incidence and described the suspected cases of paracetamol poisoning in a tertiary hospital of Spain.•We also determined the differences…”
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Non‐Chemotherapy‐Induced Agranulocytosis Detected by a Prospective Pharmacovigilance Program in a Tertiary Hospital
Published in Basic & clinical pharmacology & toxicology (01-12-2015)“…We conducted a prospective evaluation of non‐chemotherapy‐induced agranulocytosis (NIA) in a tertiary hospital in Spain. Through our Prospective…”
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Pharmacometabolomics applied to zonisamide pharmacokinetic parameter prediction
Published in Metabolomics (01-05-2018)“…Introduction Zonisamide is a new-generation anticonvulsant antiepileptic drug metabolized primarily in the liver, with subsequent elimination via the renal…”
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Nonchemotherapy drug-induced agranulocytosis in children detected by a prospective pharmacovigilance program
Published in Pediatric hematology and oncology (16-11-2016)“…Objectives: A prospective evaluation of nonchemotherapy drug-induced agranulocytosis (DIA) cases, which are infrequent in the pediatric population. We…”
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Influence of two variants of CYP450 oxidoreductase on the stable dose of acenocoumarol in a Spanish population
Published in Pharmacogenomics (01-06-2017)“…To evaluate the influence of two variants of P450 oxidoreductase (POR), rs2868177 and , on the stable dosage of acenocoumarol. For this observational,…”
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Correction to: Pharmacometabolomics applied to zonisamide pharmacokinetic parameter prediction
Published in Metabolomics (14-06-2018)“…The original version of this article contains a mistake…”
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17
Effect of CYP 4F2 , VKORC 1 , and CYP 2C9 in Influencing Coumarin Dose: A Single‐Patient Data Meta‐Analysis in More Than 15,000 Individuals
Published in Clinical pharmacology and therapeutics (01-06-2019)“…The cytochrome P450 ( CYP ) 4F2 gene is known to influence mean coumarin dose. The aim of the present study was to undertake a meta‐analysis at the individual…”
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A New Pharmacogenetic Algorithm to Predict the Most Appropriate Dosage of Acenocoumarol for Stable Anticoagulation in a Mixed Spanish Population: e0150456
Published in PloS one (01-03-2016)“…There is a strong association between genetic polymorphisms and the acenocoumarol dosage requirements. Genotyping the polymorphisms involved in the…”
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