Search Results - "Tonelli, Federica"

Spirocyclic Benzopyran-Based Derivatives as New Anti-ischemic Activators of Mitochondrial ATP-Sensitive Potassium Channel by Breschi, Maria C, Calderone, Vincenzo, Digiacomo, Maria, Manganaro, Mariaelisa, Martelli, Alma, Minutolo, Filippo, Rapposelli, Simona, Testai, Lara, Tonelli, Federica, Balsamo, Aldo

“…Heart mitochondrial ATP-sensitive potassium channels (mito-KATP channels) are deeply implicated in the self-defense mechanism of ischemic preconditioning…”
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Structure-guided design of antibacterials that allosterically inhibit DNA gyrase by Thalji, Reema K., Raha, Kaushik, Andreotti, Daniele, Checchia, Anna, Cui, Haifeng, Meneghelli, Giovanni, Profeta, Roberto, Tonelli, Federica, Tommasi, Simona, Bakshi, Tania, Donovan, Brian T., Howells, Alison, Jain, Shruti, Nixon, Christopher, Quinque, Geoffrey, McCloskey, Lynn, Bax, Benjamin D., Neu, Margarete, Chan, Pan F., Stavenger, Robert A.

“…[Display omitted] A series of DNA gyrase inhibitors were designed based on the X-ray structure of a parent thiophene scaffold with the objective to improve…”
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New Benzopyran-Based Openers of the Mitochondrial ATP-Sensitive Potassium Channel with Potent Anti-Ischemic Properties by Breschi, Maria C, Calderone, Vincenzo, Martelli, Alma, Minutolo, Filippo, Rapposelli, Simona, Testai, Lara, Tonelli, Federica, Balsamo, Aldo

“…This study was aimed at evaluating, on a limited number of benzopyran compounds, whether the insertion of an electron-rich spirocyclic substituent at the C4…”
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Pyrrolo[1,2-a]pyrazine and pyrazolo[1,5-a]pyrazine: Novel, potent, and selective series of Vasopressin1b receptor antagonists by ARBAN, Roberto, BIANCHI, Federica, TERRENI, Silvia, TONELLI, Federica, BUSON, Alberto, CREMONESI, Susanna, DI FABIO, Romano, GENTILE, Gabriella, MICHELI, Fabrizio, PASQUARELLO, Alessandra, POZZAN, Alfonso, TARSI, Luca

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Synthesis and pharmacological characterization of 5-phenyl-2-[2-(1-piperidinylcarbonyl)phenyl]-2,3-dihydro-1H-pyrrolo[1,2-c]imidazol-1-ones: A new class of Neuropeptide S antagonists by MICHELI, Fabrizio, DI FABIO, Romano, ZARANTONELLO, Paola, ZONZINI, Laura, CAPELLI, Anna Maria, GIACOMETTI, Angelo, ROTH, Adelheid, MORO, Elisa, MERLO, Giancarlo, PAIO, Alfredo, MERLO-PICH, Emilio, TOMELLERI, Silvia, TONELLI, Federica

“…A new class of selective NPS antagonist was developed starting from a commercially available product identified by screening activities. Experimental NMR…”
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Pyrrolo[1,2- a]pyrazine and pyrazolo[1,5- a]pyrazine: Novel, potent, and selective series of Vasopressin 1b receptor antagonists by Arban, Roberto, Bianchi, Federica, Buson, Alberto, Cremonesi, Susanna, Fabio, Romano Di, Gentile, Gabriella, Micheli, Fabrizio, Pasquarello, Alessandra, Pozzan, Alfonso, Tarsi, Luca, Terreni, Silvia, Tonelli, Federica

“…Novel series of pyrrole-pyrazinone and pyrazole-pyrazinone have been identified as potent and selective Vasopressin 1b receptor antagonists. Exploration of the…”
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Synthesis and pharmacological characterization of 5-phenyl-2-[2-(1-piperidinylcarbonyl)phenyl]-2,3-dihydro-1H-pyr rolo[1,2-c]imidazol-1-ones: A new class of Neuropeptide S antagonists by Micheli, Fabrizio, Di Fabio, Romano, Giacometti, Angelo, Roth, Adelheid, Moro, Elisa, Merlo, Giancarlo, Paio, Alfredo, Merlo-Pich, Emilio, Tomelleri, Silvia, Tonelli, Federica, Zarantonello, Paola, Zonzini, Laura, Capelli, Anna Maria

“…A new class of selective NPS antagonist was developed starting from a commercially available product identified by screening activities. Experimental NMR…”
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Synthesis and pharmacological characterization of 5-phenyl-2-[2-(1-piperidinylcarbonyl)phenyl]-2,3-dihydro-1 H-pyrrolo[1,2- c]imidazol-1-ones: A new class of Neuropeptide S antagonists by Micheli, Fabrizio, Di Fabio, Romano, Giacometti, Angelo, Roth, Adelheid, Moro, Elisa, Merlo, Giancarlo, Paio, Alfredo, Merlo-Pich, Emilio, Tomelleri, Silvia, Tonelli, Federica, Zarantonello, Paola, Zonzini, Laura, Capelli, Anna Maria

“…A new lead series was identified in the NPS antagonist field. The compound was prepared following up experimental observations rationalized with computational…”
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