Search Results - "Tone, Luiz G."

Differential expression of 12 histone deacetylase (HDAC) genes in astrocytomas and normal brain tissue: class II and IV are hypoexpressed in glioblastomas by Lucio-Eterovic, Agda K B, Cortez, Maria A A, Valera, Elvis T, Motta, Fabio J N, Queiroz, Rosane G P, Machado, Helio R, Carlotti, Jr, Carlos G, Neder, Luciano, Scrideli, Carlos A, Tone, Luiz G

“…Glioblastoma is the most lethal primary malignant brain tumor. Although considerable progress has been made in the treatment of this aggressive tumor, the…”
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Indisulam Reduces Viability and Regulates Apoptotic Gene Expression in Pediatric High-Grade Glioma Cells by Monção, Caio C D, Scrideli, Carlos A, Andrade, Augusto F, Viapiano, Mariano S, Carlotti, Carlos G, Moreno, Daniel Antunes, Baroni, Mirella, Tone, Luiz G, Teixeira, Silvia A

“…Pediatric high-grade glioma (pHGG) is one of the most aggressive brain tumors. Treatment includes surgery, radiotherapy, chemotherapy, or combination therapy…”
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Benefits of the Intermittent Use of 6-Mercaptopurine and Methotrexate in Maintenance Treatment for Low-Risk Acute Lymphoblastic Leukemia in Children: Randomized Trial From the Brazilian Childhood Cooperative Group—Protocol ALL-99 by Brandalise, Silvia R, Pinheiro, Vitória R, Aguiar, Simone S, Matsuda, Eduardo I, Otubo, Rosemary, Yunes, José A, Pereira, Waldir V, Carvalho, Eny G, Cristofani, Lilian M, Souza, Marcelo S, Lee, Maria L, Dobbin, Jane A, Pombo-de-Oliveira, Maria S, Lopes, Luiz F, Melnikoff, Katharina N T, Brunetto, Algemir L, Tone, Luiz G, Scrideli, Carlos A, Morais, Vera L L, Viana, Marcos B

“…PURPOSE To describe event-free survival (EFS) and toxicities in children with low-risk acute lymphoblastic leukemia (ALL) assigned to receive either continuous…”
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Zebularine induces chemosensitization to methotrexate and efficiently decreases AhR gene methylation in childhood acute lymphoblastic leukemia cells by Andrade, Augusto F, Borges, Kleiton S, Castro-Gamero, Angel M, Silveira, Vanessa S, Suazo, Veridiana K, Oliveira, Jaqueline C, Moreno, Daniel A, de Paula Queiroz, Rosane G, Scrideli, Carlos A, Tone, Luiz G

“…Acute lymphoblastic leukemia (ALL) is the most common hematologic malignancy in childhood. Despite the advances in treatment, about 20% of patients relapse…”
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A simplified minimal residual disease polymerase chain reaction method at early treatment points can stratify children with acute lymphoblastic leukemia into good and poor outcome groups by Scrideli, Carlos A, Assumpcao, Juliana G, Ganazza, Monica A, Araujo, Marcela, Toledo, Silvia R, Lee, Maria Lucia M, Delbuono, Elisabete, Petrilli, Antonio S, Queiroz, Rosane P, Biondi, Andrea, Viana, Marcos B, Yunes, Jose A, Brandalise, Silvia R, Tone, Luiz G

“…1 Department of Pediatrics, Ribeirao Preto Medical School, University of São Paulo, Ribeirao Preto, Brazil 2 Centro Infantil Boldrini, Campinas, Brazil 3…”
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MSI2 expression in adrenocortical carcinoma: Association with unfavorable prognosis and correlation with steroid and immune‐related pathways by Veronez, Luciana C., Chagas, Pablo F., Corrêa, Carolina A. P., Baroni, Mirella, Silva, Keteryne R., Nagano, Luis F., Borges, Kleiton S., Queiroz, Rosane G. P., Tone, Luiz G., Scrideli, Carlos A.

“…Adrenocortical carcinoma (ACC) is a rare, but highly aggressive cancer of the adrenal cortex with a generally poor prognosis. Despite being rare, completely…”
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Detection by a simple and cheaper methodology of Ik6 and Ik10 isoforms of the IKZF1 gene is highly associated with a poor prognosis in B‐lineage paediatric acute lymphoblastic leukaemia by Moreira, Larissa B. P., Queiróz, Rosane de P., Suazo, Veridiana K., Perna, Elisabeth, Brandalise, Silvia R., Yunes, José A., Tone, Luiz G., Scrideli, Carlos A.

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Identification of HDAC4 as a potential therapeutic target and prognostic biomarker for ZFTA-fused ependymomas by de Sousa, Graziella R., Salomão, Karina B., Nagano, Luis F. P., Riemondy, Kent A., Chagas, Pablo S., Veronez, Luciana C., Saggioro, Fabiano P., Marie, Suely K. N., Yunes, José A., Cardinalli, Izilda A., Brandalise, Silvia R., de Paula Queiroz, Rosane G., Scrideli, Carlos A., Donson, Andrew M., Foreman, Nicholas K., Tone, Luiz G., Valera, Elvis T.

“…Members of the HDAC family are predictive biomarkers and regulate the tumorigenesis in several cancers. However, the role of these genes in the biology of…”
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The aurora kinase inhibitor AMG 900 increases apoptosis and induces chemosensitivity to anticancer drugs in the NCI-H295 adrenocortical carcinoma cell line by Borges, Kleiton S, Andrade, Augusto F, Silveira, Vanessa S, Marco Antonio, David S, Vasconcelos, Elton J.R, Antonini, Sonir R.R, Tone, Luiz G, Scrideli, Carlos A

“…Adrenocortical tumor (ACT) is a malignancy with a low incidence rate and the current therapy for advanced disease has a limited impact on overall patient…”
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Gene expression profile analysis of primary glioblastomas and non-neoplastic brain tissue: identification of potential target genes by oligonucleotide microarray and real-time quantitative PCR by Scrideli, Carlos A., Carlotti, Carlos G., Okamoto, Oswaldo K., Andrade, Vanessa S., Cortez, Maria A. A., Motta, Fábio J. N., Lucio-Eterovic, Agda K., Neder, Luciano, Rosemberg, Sérgio, Oba-Shinjo, Sueli M., Marie, Suely K. N., Tone, Luíz G.

“…The prognosis of glioblastomas is still extremely poor and the discovery of novel molecular therapeutic targets can be important to optimize treatment…”
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Caesarean sections, prenatal and postnatal conditions and childhood acute lymphoblastic leukaemia: A case-control study in the State of São Paulo, Brazil by Junqueira, Maria Elizangela Ramos, de Oliveira, Claúdia T., Tone, Luiz G., Lee, Maria Lúcia de M., de Andréa, Maria Lydia M., Bruniera, Paula, Epelman, Sidnei, Odone Filho, Vicente, Bonilha, Eliana de A., de Freitas, Marina, Okamura, Mirna N., Vico, Eneida R., Stevens, Anthony P., Rabello Neto, Dácio de L, Wünsch Filho, Victor

“…•No statistically significant associations between caesarean section and ALL were observed.•Children born by caesarean section had a slight non-significant…”
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BI 6727 and GSK461364 suppress growth and radiosensitize osteosarcoma cells, but show limited cytotoxic effects when combined with conventional treatments by Bogado, Rodrigo F.E, Pezuk, Julia A, de Oliveira, Harley F, Tone, Luiz G, Brassesco, María S

“…Polo-like kinase 1 (PLK1), a key regulator of mitosis, is often overexpressed in childhood cancers and is associated with poor prognosis. Previous reports have…”
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Wnt/β-Catenin Pathway Deregulation in Childhood Adrenocortical Tumors by Leal, Letícia F, Mermejo, Lívia M, Ramalho, Leandra Z, Martinelli, Carlos E, Yunes, José A, Seidinger, Ana Luiza, Mastellaro, Maria José, Cardinalli, Izilda A, Brandalise, Silvia R, Moreira, Ayrton C, Tone, Luiz G, Scrideli, Carlos A, Castro, Margaret, Antonini, Sonir R

“…Context: CTNNB1/β-catenin mutations and activation of Wnt/β-catenin pathway are frequent in adult adrenocortical tumors (ACT), but data on childhood ACT are…”
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Cytostatic in vitro Effects of DTCM-Glutarimide on Bladder Carcinoma Cells by Brassesco, Maria S, Pezuk, Julia A, Morales, Andressa G, De Oliveira, Jaqueline C, Valera, Elvis T, Da Silva, Glenda N, De Oliveira, Harley F, Scrideli, Carlos A, Umezawa, Kazuo, Tone, Luiz G

“…Bladder cancer is a common malignancy worldwide. Despite the increased use of cisplatin-based combination therapy, the outcomes for patients with advanced…”
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Low expression of HLA-DRA, HLA-DPA1, and HLA-DPB1 is associated with poor prognosis in pediatric adrenocortical tumors (ACT) by Leite, Fabíola A., Lira, Regia C. P., Fedatto, Paola F., Antonini, Sonir R. R., Martinelli Jr, Carlos E., de Castro, Margaret, Neder, Luciano, Ramalho, Leandra N. Z., Tucci Jr, Silvio, Mastelaro, Maria J., Seidinger, Ana L., Cardinalli, Izilda A., Yunes, José A., Brandalise, Silvia R., Tone, Luiz G., Scrideli, Carlos A.

“…Background Low expression of HLA class II antigens has been associated with more aggressive disease in several human malignancies including adult…”
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Altered expression of noncanonical Wnt pathway genes in paediatric and adult adrenocortical tumours by Mermejo, Livia M., Leal, Leticia F., Colli, Leandro M., Fragoso, Maria C.B.V., Latronico, Ana C., Tone, Luiz G., Scrideli, Carlos A., Tucci, Silvio, Martinelli, Carlos E., Yunes, Jose A., Mastellaro, Maria J., Seidinger, Ana L., Brandalise, Silvia R., Moreira, Ayrton C., Ramalho, Leandra N., Antonini, Sonir R., Castro, Margaret

“…Summary Context The role of planar cell polarity (Wnt/PCP) and calcium‐dependent (Wnt/Ca) noncanonical Wnt pathways in adrenocortical tumours (ACTs) is…”
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Unraveling the expression of the oncogene YAP1, a Wnt/beta-catenin target, in adrenocortical tumors and its association with poor outcome in pediatric patients by Abduch, Rafael H, Carolina Bueno, Ana, Leal, Leticia F, Cavalcanti, Marcelo M, Gomes, Débora C, Brandalise, Silvia R, Masterallo, Maria J, Yunes, José A, Martinelli, Jr, Carlos E, Tone, Luiz G, Tucci, Silvio, Molina, Carlos A F, Ramalho, Fernando S, Moreira, Ayrton C, Cardinalli, Izilda A, Scrideli, Carlos A, Ramalho, Leandra N Z, de Castro, Margaret, Antonini, Sonir R

“…Overexpression of the oncogene yes-associated-protein-1 (YAP1) is associated with increased cell proliferation in human cancers. YAP1 is a potential target of…”
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Exposure to magnetic fields and childhood acute lymphocytic leukemia in São Paulo, Brazil by Wünsch-Filho, Victor, Pelissari, Daniele M, Barbieri, Flávio E, Sant’Anna, Leonel, de Oliveira, Claúdia T, de Mata, Juliana F, Tone, Luiz G, Lee, Maria Lúcia de M, Andréa, Maria Lydia M. de, Bruniera, Paula, Epelman, Sidnei, Filho, Vicente Odone, Kheifets, Leeka

“…Abstract Background : Epidemiological studies have identified increased risks of leukemia in children living near power lines and exposed to relatively high…”
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BI 2536-mediated PLK1 inhibition suppresses HOS and MG-63 osteosarcoma cell line growth and clonogenicity by Morales, Andressa G, Brassesco, María S, Pezuk, Julia A, Oliveira, Jaqueline C, Montaldi, Ana P, Sakamoto-Hojo, Elza T, Scrideli, Carlos A, Tone, Luiz G

“…Osteosarcoma is the most common primary malignant tumor of bone, which frequently occurs in the second decade of life. Despite the improvements in neoadjuvant…”
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The methylenetetrahydrofolate reductase C677T gene polymorphism decreases the risk of childhood acute lymphocytic leukaemia by Franco, Rendrik F., Simões, Belinda P., Tone, Luiz G., Gabellini, Sérgio M., Zago, Marco A., Falcão, Roberto P.

“…We have determined the prevalence of methylenetetrahydrofolate reductase (MTHFR) mutations C677T and A1298C in 71 children ( 15 years) with acute lymphoblastic…”
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