Search Results - "Tondolo, Juliana S. M."
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Treating Pythiosis with Antibacterial Drugs Targeting Protein Synthesis: An Overview
Published in Journal of fungi (Basel) (01-04-2024)“…This review article explores the effectiveness of antibacterial drugs that inhibit protein synthesis in treating pythiosis, a difficult-to-treat infection…”
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New insights into the in vitro susceptibility of Pythium insidiosum
Published in Antimicrobial agents and chemotherapy (01-12-2014)“…We have determined the in vitro activity of several antibacterial and antifungal drugs against Pythium insidiosum using broth microdilution (BMD), disk…”
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Chemically induced disseminated pythiosis in BALB/c mice: A new experimental model for Pythium insidiosum infection
Published in PloS one (19-05-2017)“…Pythiosis is a severe and life-threatening disease that affects humans and various animal species. We report a model of vascular/disseminated pythiosis…”
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In Vitro Synergism between Azithromycin or Terbinafine and Topical Antimicrobial Agents against Pythium insidiosum
Published in Antimicrobial agents and chemotherapy (01-08-2016)“…We describe here in vitro activity for the combination of azithromycin or terbinafine and benzalkonium, cetrimide, cetylpyridinium, mupirocin, triclosan, or…”
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In vitro synergism observed with azithromycin, clarithromycin, minocycline, or tigecycline in association with antifungal agents against Pythium insidiosum
Published in Antimicrobial agents and chemotherapy (01-09-2014)“…We describe here the in vitro activities of azithromycin, clarithromycin, minocycline, or tigecycline alone and in combination with amphotericin B,…”
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In Vitro Activities of Miltefosine and Antibacterial Agents from the Macrolide, Oxazolidinone, and Pleuromutilin Classes against Pythium insidiosum and Pythium aphanidermatum
Published in Antimicrobial agents and chemotherapy (01-03-2018)“…We tested 29 isolates of and one isolate of to investigate their susceptibility to miltefosine and antibacterial drugs from the macrolide, oxazolidinone, and…”
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Efficacy of Azithromycin and Miltefosine in Experimental Systemic Pythiosis in Immunosuppressed Mice
Published in Antimicrobial agents and chemotherapy (01-01-2019)“…We evaluated the efficacy of azithromycin (50 mg/kg, every 12 h [q12h] orally) and miltefosine (25 mg/kg, q24h orally) treatments in an experimental model of…”
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In Vitro and In Vivo Antimicrobial Activities of Minocycline in Combination with Azithromycin, Clarithromycin, or Tigecycline against Pythium insidiosum
Published in Antimicrobial agents and chemotherapy (01-01-2016)“…The present study investigated the in vitro and the in vivo interactions among azithromycin, clarithromycin, minocycline, and tigecycline against Pythium…”
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In Vitro Assessment of Antifungal Drugs and Sulfamethoxazole-Trimethoprim against Clinical Isolates of Conidiobolus lamprauges
Published in Antimicrobial agents and chemotherapy (01-04-2018)Get full text
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In vivo effect of minocycline alone and in combination with immunotherapy against pythium insidiosum
Published in Veterinary microbiology (01-04-2020)“…•Minocycline has fungistatic activity against Pythium insidiosum.•Minocycline in combination with immunotherapy is an effective treatment strategy for…”
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Clioquinol and 8-hydroxyquinoline-5-sulfonamide derivatives damage the cell wall of Pythium insidiosum
Published in Journal of applied microbiology (14-12-2022)“…To evaluate the antimicrobial activity and to determine the pharmacodynamic characteristics of three 8-hydroxyquinoline derivatives (8-HQs) against Pythium…”
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Immunotherapy based on Pythium insidiosum mycelia drives a Th1/Th17 response in mice
Published in Medical mycology (Oxford) (10-11-2020)“…Abstract Pythium insidiosum is an oomycete that affects mammals, especially humans and horses, causing a difficult-to-treat disease. Typically, surgical…”
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Extraction, characterization and biological activity of a (1,3)(1,6)-β-d-glucan from the pathogenic oomycete Pythium insidiosum
Published in Carbohydrate polymers (10-02-2017)“…•A branched (1,3)(1,6)-β-d-glucan was extracted from Pythium insidiosum cell wall.•(1,3)(1,6)-β-d-glucan significantly stimulated the lymphocyte…”
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Dendritic cells pulsed with Pythium insidiosum (1,3)(1,6)-β-glucan, Heat-inactivated zoospores and immunotherapy prime naïve T cells to Th1 differentiation in vitro
Published in Immunobiology (1979) (01-03-2018)“…•Pythiosis is a life-threatening and severe disease.•There are no gold standard treatments for pythiosis.•DCs pulsed vaccine against pythiosis is an unexplored…”
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In vitro assessment of antifungal, antibacterial, and antiprotozoal drugs against clinical isolates of Conidiobolus lamprauges
Published in Medical mycology (Oxford) (01-07-2019)“…Abstract We have determined the in vitro activity of antifungal, antibacterial, and antiprotozoal drugs alone and in combination against seven Conidiobolus…”
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An experimental murine model of otitis and dermatitis caused by Malassezia pachydermatis
Published in Mycoses (01-12-2018)“…Summary We report a malasseziosis model in immunocompromised Swiss mice. For this model, the mice were immunosuppressed with a combination of cyclophosphamide…”
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Embryonated chicken eggs: An experimental model for Pythium insidiosum infection
Published in Mycoses (01-02-2018)“…Summary Pythiosis is a severe disease caused by Pythium insidiosum. Currently, the research on the treatment of pythiosis uses rabbits as an experimental…”
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Carboxymethylation of β-Glucan from Pythium insidiosum: Structural characterization and preliminary adsorption evaluation of DON and T2 toxin
Published in Carbohydrate research (01-01-2025)“…This study aimed to evaluate the impact of carboxymethylation on the structural and functional properties of β-glucan derived from the pathogenic oomycete…”
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Screening of antibacterial drugs for antimicrobial activity against Pythium insidiosum
Published in Medical mycology (Oxford) (01-06-2019)“…We tested 25 isolates of Pythium insidiosum to investigate their susceptibility to antibacterial drugs that act through inhibition of protein synthesis or…”
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Clioquinol and 8-hydroxyquinoline-5-sulfonamide derivatives damage the cell wall of Pythium insidiosum
Published in Journal of applied microbiology (14-12-2022)“…To evaluate the antimicrobial activity and to determine the pharmacodynamic characteristics of three 8-hydroxyquinoline derivatives (8-HQs) against Pythium…”
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