Search Results - "Tonar, Zbynek"
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Inflammatory cell infiltrates, hypoxia, vascularization, pentraxin 3 and osteoprotegerin in abdominal aortic aneurysms - A quantitative histological study
Published in PloS one (08-11-2019)“…Information about the tissue characteristics of abdominal aortic aneurysms (AAAs), some of which may be reflected in the serum, can help to elucidate AAA…”
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CTNNB1 mutations, TERT polymorphism and CD8+ cell densities in resected hepatocellular carcinoma are associated with longer time to recurrence
Published in BMC cancer (13-08-2022)“…Abstract Background Hepatocellular carcinoma (HCC) is a fatal disease characterized by early genetic alterations in telomerase reverse transcriptase promoter…”
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Porcine Liver Anatomy Applied to Biomedicine
Published in The Journal of surgical research (01-06-2020)“…Currently, there are at least 70 pure domestic pig breeds, but only certain breeds are used in biomedical research. The domestic pig liver is suitable for…”
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Mesenchymal Stromal Cell Therapy in Novel Porcine Model of Diffuse Liver Damage Induced by Repeated Biliary Obstruction
Published in International journal of molecular sciences (21-04-2021)“…In liver surgery, biliary obstruction can lead to secondary biliary cirrhosis, a life-threatening disease with liver transplantation as the only curative…”
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Complex genetic and histopathological study of 15 patient-derived xenografts of aggressive lymphomas
Published in Laboratory investigation (01-09-2022)“…Non-Hodgkin lymphomas (NHL) represent the most common hematologic malignancies. Patient-derived xenografts (PDXs) are used for various aspects of translational…”
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Absence of Microbiota (Germ-Free Conditions) Accelerates the Atherosclerosis in ApoE-Deficient Mice Fed Standard Low Cholesterol Diet
Published in Journal of Atherosclerosis and Thrombosis (01-01-2010)“…Aim: The aim of our work was to determine the influence of intestinal bacteria on the development of atherosclerotic lesions using apolipoprotein E…”
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Experimental fortification of intestinal anastomoses with nanofibrous materials in a large animal model
Published in Scientific reports (24-01-2020)“…Anastomotic leakage is a severe complication in gastrointestinal surgery. It is often a reason for reoperation together with intestinal passage blockage due to…”
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Osteoinductive 3D scaffolds prepared by blend centrifugal spinning for long-term delivery of osteogenic supplements
Published in RSC advances (13-06-2018)“…Bone regeneration is a long-term process requiring proper scaffolding and drug delivery systems. The current study delivers a three-dimensional (3D) scaffold…”
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Generating standardized image data for testing and calibrating quantification of volumes, surfaces, lengths, and object counts in fibrous and porous materials using X‐ray microtomography
Published in Microscopy research and technique (01-06-2018)“…Quantification of the structure and composition of biomaterials using micro‐CT requires image segmentation due to the low contrast and overlapping radioopacity…”
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Vancomycin-Loaded Collagen/Hydroxyapatite Layers Electrospun on 3D Printed Titanium Implants Prevent Bone Destruction Associated with S. epidermidis Infection and Enhance Osseointegration
Published in Biomedicines (10-05-2021)“…The aim of the study was to develop an orthopedic implant coating in the form of vancomycin-loaded collagen/hydroxyapatite layers (COLHA+V) that combine the…”
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Hyperbaric oxygen enhances collagen III formation in wound of ZDF rat
Published in Physiological research (29-11-2021)“…Diabetic foot ulcer (DFU) is a serious complication of diabetes and hyperbaric oxygen therapy (HBOT) is also considered in comprehensive treatment. The…”
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Using virtual microscopy for the development of sampling strategies in quantitative histology and design‐based stereology
Published in Anatomia, histologia, embryologia (01-01-2022)“…Only a fraction of specimens under study are usually selected for quantification in histology. Multilevel sampling or tissue probes, slides and fields of view…”
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Hydrogel Containing Anti-CD44-Labeled Microparticles, Guide Bone Tissue Formation in Osteochondral Defects in Rabbits
Published in Nanomaterials (Basel, Switzerland) (31-07-2020)“…Hydrogels are suitable for osteochondral defect regeneration as they mimic the viscoelastic environment of cartilage. However, their biomechanical properties…”
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An Assessment of Blood Vessel Remodeling of Nanofibrous Poly(ε-Caprolactone) Vascular Grafts in a Rat Animal Model
Published in Journal of functional biomaterials (01-02-2023)“…The development of an ideal vascular prosthesis represents an important challenge in terms of the treatment of cardiovascular diseases with respect to which…”
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Electrospun vascular grafts fabricated from poly(L-lactide-co-ε-caprolactone) used as a bypass for the rabbit carotid artery
Published in Biomedical materials (Bristol) (21-09-2018)“…The study involved the electrospinning of the copolymer poly(L-lactide-co-ε-caprolactone) (PLCL) into tubular grafts. The subsequent material characterization,…”
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Microvessel density of mantle cell lymphoma. A retrospective study of its prognostic role and the correlation with the Ki-67 and the mantle cell lymphoma international prognostic index in 177 cases
Published in Virchows Archiv : an international journal of pathology (01-11-2014)“…The clinical course and therapy of mantle cell lymphoma (MCL) are heterogeneous and often unsatisfactory. Prognostic factors are needed to stratify the…”
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Variations in Swine Liver Anatomy
Published in Transplantation (01-06-2024)Get full text
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Asymptomatic abdominal aortic aneurysms show histological signs of progression: a quantitative histochemical analysis
Published in Pathobiology (Basel) (01-01-2013)“…Abdominal aortic aneurysm (AAA) is a serious disease due to its covert nature, relatively high prevalence and fatal prognosis in the case of rupture. To obtain…”
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Numerical and length densities of microvessels in the human brain: Correlation with preferential orientation of microvessels in the cerebral cortex, subcortical grey matter and white matter, pons and cerebellum
Published in Journal of chemical neuroanatomy (01-03-2018)“…•Differences in microvessel densities among 16 anatomical brain regions were mapped.•The numerical and length densities of brain microvessels are mutually…”
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Parasympathetic regulation of heart rate in rats after 5/6 nephrectomy is impaired despite functionally intact cardiac vagal innervation
Published in Nephrology, dialysis, transplantation (01-08-2009)“…Background. Chronic renal failure is frequently associated with a high risk of sudden cardiac death due to dysfunction of the autonomic nervous system. The…”
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