Search Results - "Tomsik Pavel"

Ferns and Lycopods—A Potential Treasury of Anticancer Agents but Also a Carcinogenic Hazard by Tomsik, Pavel

“…Many species of seedless vascular plants—ferns and lycopods—have been used as food and folk medicine since ancient times. Some of them have become the focus of…”
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The Steroidal Glycoalkaloids from Solanaceae: Toxic Effect, Antitumour Activity and Mechanism of Action by Sucha, Lenka, Tomsik, Pavel

“…Steroidal glycoalkaloids present in Solanaceae are toxic compounds biosynthesised for the protection of the plants. However, many health benefits of these…”
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Ruthenium(II) Complex Containing a Redox-Active Semiquinonate Ligand as a Potential Chemotherapeutic Agent: From Synthesis to In Vivo Studies by Notaro, Anna, Frei, Angelo, Rubbiani, Riccardo, Jakubaszek, Marta, Basu, Uttara, Koch, Severin, Mari, Cristina, Dotou, Mazzarine, Blacque, Olivier, Gouyon, Jérémie, Bedioui, Fethi, Rotthowe, Nils, Winter, Rainer F, Goud, Bruno, Ferrari, Stefano, Tharaud, Mickaël, Řezáčová, Martina, Humajová, Jana, Tomšík, Pavel, Gasser, Gilles

“…Chemotherapy remains one of the dominant treatments to cure cancer. However, due to the many inherent drawbacks, there is a search for new chemotherapeutic…”
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The effects of β-caryophyllene oxide and trans-nerolidol on the efficacy of doxorubicin in breast cancer cells and breast tumor-bearing mice by Hanušová, Veronika, Caltová, Kateřina, Svobodová, Hana, Ambrož, Martin, Skarka, Adam, Murínová, Natálie, Králová, Věra, Tomšík, Pavel, Skálová, Lenka

“…[Display omitted] One approach to improve effect of chemotherapy is combination of classical cytostatic drugs with natural compounds, e. g. sesquiterpenes. In…”
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Chlorambucil conjugates of dinuclear p-cymene ruthenium trithiolato complexes: synthesis, characterization and cytotoxicity study in vitro and in vivo by Stíbal, David, Therrien, Bruno, Süss-Fink, Georg, Nowak-Sliwinska, Patrycja, Dyson, Paul J., Čermáková, Eva, Řezáčová, Martina, Tomšík, Pavel

“…Four diruthenium trithiolato chlorambucil conjugates have been prepared via Steglich esterification from chlorambucil and the corresponding trithiolato…”
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Development of an HPLC fluorescence method for determination of boldine in plasma, bile and urine of rats and identification of its major metabolites by LC–MS/MS by Hroch, Miloš, Mičuda, Stanislav, Cermanová, Jolana, Chládek, Jaroslav, Tomšík, Pavel

“…•Major boldine metabolites were identified in rats for the first time.•A universal method for assay in plasma, bile and urine was developed.•Fluorescence and…”
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Boldine Inhibits Mouse Mammary Carcinoma In Vivo and Human MCF-7 Breast Cancer Cells In Vitro by Tomšík, Pavel, Mičuda, Stanislav, Muthná, Darina, Čermáková, Eva, Havelek, Radim, Rudolf, Emil, Hroch, Miloš, Kadová, Zuzana, Řezáčová, Martina, Ćmielová, Jana, Živný, Pavel

“…Boldine is an aporphine alkaloid widely consumed in the folk medicine of some regions. Its anticancer potential has been shown but not yet elucidated. We…”
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Competency-based approach to human resources management by LIŠKOVÁ, Stanislava, TOMŠÍK, Pavel

“…The paper deals with the competency approach to human resources management. The approach is seen as one of the possibilities to effectively manage work…”
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In-vitro and in-vivo evaluation of the anticancer activity of diruthenium-2, a new trithiolato arene ruthenium complex [(η6-p-MeC6H4Pri)2Ru2(μ-S-p-C6H4OH)3]Cl by Muthná, Darina, Tomšík, Pavel, Havelek, Radim, Köhlerová, Renata, Kasilingam, Vidhya, Čermáková, Eva, Stíbal, David, Řezáčová, Martina, Süss-Fink, Georg

“…In the present study, we investigated the anticancer action of the trithiolato arene ruthenium complex, [(η-p-MeC6H4Pr)2Ru2(μ-S-p-C6H4OH)3]Cl, named…”
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[(p-MeC6H4Pr )2Ru2(SC6H4-p-Bu )3]Cl (diruthenium-1), a dinuclear arene ruthenium compound with very high anticancer activity: An in vitro and in vivo study by Tomšík, Pavel, Muthná, Darina, Řezáčová, Martina, Mičuda, Stanislav, Ćmielová, Jana, Hroch, Miloš, Endlicher, René, Červinková, Zuzana, Rudolf, Emil, Hann, Stephan, Stíbal, David, Therrien, Bruno, Süss-Fink, Georg

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Consumers' perception of the health aspects of organic food by KUTNOHORSKÁ, Olga, TOMŠÍK, Pavel

“…Organic foods are grown using the principles of organic agriculture that are produced, processed and packaged without using chemicals. They have been accepted…”
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Factors influencing employment for tertiary education graduates at the selected universities by STOJANOVÁ, Hana, TOMŠÍK, Pavel

“…The graduates of tertiary education level are one of the risk groups in the economically active age, who have a significant problem to find a job in the labour…”
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Management of wine production with regard to its implementation into the wine markets of the Czech Republic by TOMŠÍK, Pavel, SEDLO, Jiří

“…The Czech Republic is a country, in which the production of wine covers approximately one third of the total demand. The current production potential of the…”
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Factors of profitability of the grapes production by TOMSIK, Pavel, STOJANOVA, Hana, SEDLO, Jiri, VAJCNEROVA, Ida

“…The paper analyses the relationships between the profitability of viticulture on the one hand and the sugar content and grapes yield in viticulture in the…”
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In vivo effect of oracin on doxorubicin reduction, biodistribution and efficacy in Ehrlich tumor bearing mice by Hanušová, Veronika, Tomšík, Pavel, Kriesfalusyová, Lenka, Pakostová, Alena, Boušová, Iva, Skálová, Lenka

“…The limitation of carbonyl reduction represents one possible way to increase the effectiveness of anthracycline doxorubicin (DOX) in cancer cells and decrease…”
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New strategic alliances of wine producers in the Czech Republic by TOMŠÍK, Pavel, PROKEŠ, Martin

“…The paper describes the main reasons for the formation of new regional association of wineries, based on a different origin of wines in the wine region of…”
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L-rhamnose and L-fucose suppress cancer growth in mice by Tomsik Pavel, Soukup Tomas, Cermakova Eva, Micuda Stanislav, Niang Mohamed, Sucha Lenka, Rezacova Martina

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Alpha-tomatine activates cell cycle checkpoints in the absence of DNA damage in human leukemic MOLT-4 cells by Kúdelová, Jana, Seifrtová, Martina, Suchá, Lenka, Tomšík, Pavel, Havelek, Radim, Řezáčová, Martina

“…Alpha-tomatine is a major glycoalkaloid found in the roots, leaves, stems and fruit of tomatoes Lycopersicon esculentum. Recently, alpha-tomatine has been…”
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Changes of the varietal structure of vineyards in the Czech Republic by Chladkova, H., Mendelova Univ., Brno (Czech Republic). Ustav Managementu, Tomsik, P., Mendelova Univ., Brno (Czech Republic). Ustav Managementu, Sedlo, J., Svaz Vinaru, Velke Bilovice (Czech Republic)

“…The paper describes changes in the structure of varieties grown in the Czech Republic. The authors examine the development taking place in this domain within…”
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Effect of L-carnitine against acute mitoxantrone toxicity in mice by Niang Mohamed, Tomšík Pavel, Mělka Milan, Stoklasová Alena, Cerman Jaroslav, Šišpera Ludìk

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