Search Results - "Tompkins, Kassidy J."

Molecular underpinnings of ssDNA specificity by Rep HUH-endonucleases and implications for HUH-tag multiplexing and engineering by Tompkins, Kassidy J, Houtti, Mo, Litzau, Lauren A, Aird, Eric J, Everett, Blake A, Nelson, Andrew T, Pornschloegl, Leland, Limón-Swanson, Lidia K, Evans, Robert L, Evans, Karen, Shi, Ke, Aihara, Hideki, Gordon, Wendy R

“…Abstract Replication initiator proteins (Reps) from the HUH-endonuclease superfamily process specific single-stranded DNA (ssDNA) sequences to initiate rolling…”
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Watson-Crick Base-Pairing Requirements for ssDNA Recognition and Processing in Replication-Initiating HUH Endonucleases by Smiley, Adam T, Tompkins, Kassidy J, Pawlak, Matthew R, Krueger, August J, Evans, 3rd, Robert L, Shi, Ke, Aihara, Hideki, Gordon, Wendy R

“…Replication-initiating HUH endonucleases (Reps) are sequence-specific nucleases that cleave and rejoin single-stranded DNA (ssDNA) during rolling-circle…”
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The crystal structure of the human smacovirus 1 Rep domain by Limón, Lidia K., Shi, Ke, Dao, Amy, Rugloski, Jacob, Tompkins, Kassidy J., Aihara, Hideki, Gordon, Wendy R., Evans, Robert L.

“…Replication initiator proteins (Reps) from the HUH endonuclease family process specific single‐stranded DNA sequences to initiate rolling‐circle replication in…”
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Enhanced Molecular Tension Sensor Based on Bioluminescence Resonance Energy Transfer (BRET) by Aird, Eric J, Tompkins, Kassidy J, Ramirez, Maria Paz, Gordon, Wendy R

“…Molecular tension sensors measure piconewton forces experienced by individual proteins in the context of the cellular microenvironment. Current genetically…”
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HUHgle: An Interactive Substrate Design Tool for Covalent Protein-ssDNA Labeling Using HUH-Tags by Smiley, Adam T., Babilonia-Díaz, Natalia S., Hughes, Aspen J., Lemmex, Andrew C. D., Anderson, Michael J. M., Tompkins, Kassidy J., Gordon, Wendy R.

“…HUH-tags have emerged as versatile fusion partners that mediate sequence specific protein-ssDNA bioconjugation through a simple and efficient reaction. Here we…”
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The Need for Speed: Run-On Oligomer Filament Formation Provides Maximum Speed with Maximum Sequestration of Activity by Barahona, Claudia J, Basantes, L Emilia, Tompkins, Kassidy J, Heitman, Desirae M, Chukwu, Barbara I, Sanchez, Juan, Sanchez, Jonathan L, Ghadirian, Niloofar, Park, Chad K, Horton, N C

“…Here, we investigate an unusual antiviral mechanism developed in the bacterium SgrAI is a type II restriction endonuclease that forms run-on oligomer filaments…”
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Probing the Mechanosensing Mechanism of GPR56 to Understand Adhesion GPCR-Related Disease Pathogenesis by Tompkins, Kassidy J.

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Development of a BRET-Based Molecular Tension Sensor to Study Altered Tensions in Disease Pathogenesis by Aird, Eric J., Tompkins, Kassidy J., Gordon, Wendy R.

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