Search Results - "Tomoyuki Akiyama"

A storm of fast (40-150Hz) oscillations during hypsarrhythmia in West syndrome by Kobayashi, Katsuhiro, Akiyama, Tomoyuki, Oka, Makio, Endoh, Fumika, Yoshinaga, Harumi

“…Objective Fast oscillations (FOs) were first explored from scalp electroencephalographic (EEG) data from hypsarrhythmia in West syndrome (infantile spasms) to…”
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High-frequency oscillations in a spectrum of pediatric epilepsies characterized by sleep-activated spikes in scalp EEG by Ohuchi, Yuji, Akiyama, Tomoyuki, Matsuhashi, Masao, Kobayashi, Katsuhiro

“…•Scalp ripples were detected from various types of pediatric epilepsies with sleep-activated spikes.•Sleep spikes were heavily loaded with ripples during young…”
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Action of antiepileptic drugs on neurons by Kobayashi, Katsuhiro, Endoh, Fumika, Ohmori, Iori, Akiyama, Tomoyuki

“…The recent development of various new antiepileptic drugs (AEDs) has provided a wide range of therapeutic strategies for epilepsy. Information regarding the…”
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Non-Gaussianity Detection of EEG Signals Based on a Multivariate Scale Mixture Model for Diagnosis of Epileptic Seizures by Furui, Akira, Onishi, Ryota, Takeuchi, Akihito, Akiyama, Tomoyuki, Tsuji, Toshio

“…Objective: The detection of epileptic seizures from scalp electroencephalogram (EEG) signals can facilitate early diagnosis and treatment. Previous studies…”
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Exclusion of the Possibility of "False Ripples" From Ripple Band High-Frequency Oscillations Recorded From Scalp Electroencephalogram in Children With Epilepsy by Kobayashi, Katsuhiro, Shibata, Takashi, Tsuchiya, Hiroki, Akiyama, Tomoyuki

“…Ripple-band epileptic high-frequency oscillations (HFOs) can be recorded by scalp electroencephalography (EEG), and tend to be associated with epileptic…”
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Epileptic Seizure Detection Using a Recurrent Neural Network With Temporal Features Derived From a Scale Mixture EEG Model by Furui, Akira, Onishi, Ryota, Akiyama, Tomoyuki, Tsuji, Toshio

“…Automated detection of epileptic seizures from scalp Electroencephalogram (EEG) is crucial for improving epilepsy diagnosis and management. This paper presents…”
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Artificial Intelligence-based Detection of Epileptic Discharges from Pediatric Scalp Electroencephalograms: A Pilot Study by Kobayashi, Katsuhiro, Shibata, Takashi, Tsuchiya, Hiroki, Akiyama, Tomoyuki

“…We developed an artificial intelligence (AI) technique to identify epileptic discharges (spikes) in pediatric scalp electroencephalograms (EEGs). We built a…”
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Identification of new biomarkers of pyridoxine-dependent epilepsy by GC/MS-based urine metabolomics by Kuhara, Tomiko, Akiyama, Tomoyuki, Ohse, Morimasa, Koike, Takayoshi, Shibasaki, Jun, Imai, Katsumi, Cooper, ArthurJ.L.

“…α-Aminoadipic semialdehyde and its cyclic form (Δ1-piperideine-6-carboxylate) accumulate in patients with α-aminoadipic semialdehyde dehydrogenase (AASADH;…”
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Longitudinal correspondence of epilepsy and scalp EEG fast (40–200 Hz) oscillations in pediatric patients with tuberous sclerosis complex by Tsuchiya, Hiroki, Endoh, Fumika, Akiyama, Tomoyuki, Matsuhashi, Masao, Kobayashi, Katsuhiro

“…Epilepsy associated with tuberous sclerosis complex (TSC) has very complex clinical characteristics. Scalp electroencephalogram (EEG) fast (40–200 Hz)…”
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A study on the relationship between non-epileptic fast (40 – 200 Hz) oscillations in scalp EEG and development in children by Oka, Makio, Kobayashi, Katsuhiro, Shibata, Takashi, Tsuchiya, Hiroki, Hanaoka, Yoshiyuki, Akiyama, Mari, Morooka, Teruko, Matsuhashi, Masao, Akiyama, Tomoyuki

“…Physiological gamma and ripple activities may be linked to neurocognitive functions. This study investigated the relationship between development and…”
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Focal resection of fast ripples on extraoperative intracranial EEG improves seizure outcome in pediatric epilepsy by Akiyama, Tomoyuki, McCoy, Bláthnaid, Go, Cristina Y., Ochi, Ayako, Elliott, Irene M., Akiyama, Mari, Donner, Elizabeth J., Weiss, Shelly K., Snead, O. Carter, Rutka, James T., Drake, James M., Otsubo, Hiroshi

“…Summary Purpose:  High‐frequency oscillations (HFOs), termed ripples at 80–200 Hz and fast ripples (FRs) at >200/250 Hz, recorded by intracranial…”
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Predictive factors for relapse of epileptic spasms after adrenocorticotropic hormone therapy in West syndrome by Hayashi, Yumiko, Yoshinaga, Harumi, Akiyama, Tomoyuki, Endoh, Fumika, Ohtsuka, Yoko, Kobayashi, Katsuhiro

“…Abstract Purpose To investigate whether serial electroencephalographic (EEG) findings can predict relapse of epileptic spasms after synthetic…”
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Differential diagnosis of nonepileptic twilight state with convulsive manifestations after febrile seizures by Miyahara, Hiroyuki, Akiyama, Tomoyuki, Waki, Kenji, Arakaki, Yoshio

“…Nonepileptic twilight state with convulsive manifestations (NETC) is a nonepileptic state following a febrile seizure (FS), which may be misdiagnosed as a…”
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Findings of amplitude-integrated electroencephalogram recordings and serum vitamin B6 metabolites in perinatal lethal hypophosphatasia during enzyme replacement therapy by Ishiguro, Tomonori, Sugiyama, Yuichiro, Ueda, Kazuto, Muramatsu, Yukako, Tsuda, Hiroyuki, Kotani, Tomomi, Michigami, Toshimi, Tachikawa, Kanako, Akiyama, Tomoyuki, Hayakawa, Masahiro

“…Hypophosphatasia (HPP) is a rare disorder caused by low serum tissue non-specific alkaline phosphatase (ALP) activity due to hypomorphic mutations in the ALPL…”
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Genomic backgrounds of Japanese patients with undiagnosed neurodevelopmental disorders by Yamamoto, Toshiyuki, Imaizumi, Taichi, Yamamoto-Shimojima, Keiko, Lu, Yongping, Yanagishita, Tomoe, Shimada, Shino, Chong, Pin Fee, Kira, Ryutaro, Ueda, Riyo, Ishiyama, Akihiko, Takeshita, Eri, Momosaki, Ken, Ozasa, Shiro, Akiyama, Tomoyuki, Kobayashi, Katsuhiro, Oomatsu, Hiroo, Kitahara, Hikaru, Yamaguchi, Tokito, Imai, Katsumi, Kurahashi, Hirokazu, Okumura, Akihisa, Oguni, Hirokazu, Seto, Toshiyuki, Okamoto, Nobuhiko

“…Recently, many genes related to neurodevelopmental disorders have been identified by high-throughput genomic analysis; however, a comprehensive understanding…”
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A Japanese single-center experience of the efficacy and safety of asfotase alfa in pediatric-onset hypophosphatasia by Sugiyama, Yohei, Watanabe, Taijiro, Tajika, Makiko, Matsuhashi, Tetsuro, Shimura, Masaru, Fushimi, Takuya, Ichimoto, Keiko, Matsunaga, Ayako, Ebihara, Tomohiro, Tsuruoka, Tomoko, Akiyama, Tomoyuki, Murayama, Kei

“…Hypophosphatasia (HPP) is a rare inherited metabolic disorder caused by mutations in the ALPL gene, which encodes tissue nonspecific alkaline phosphatase. The…”
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Vitamin B6 in acute encephalopathy with biphasic seizures and late reduced diffusion by Akiyama, Tomoyuki, Toda, Soichiro, Kimura, Nobusuke, Mogami, Yukiko, Hanaoka, Yoshiyuki, Tokorodani, Chiho, Ito, Tomoshiro, Miyahara, Hiroyuki, Hyodo, Yuki, Kobayashi, Katsuhiro

“…The initial presentation of acute encephalopathy with biphasic seizures and late reduced diffusion (AESD) is indistinguishable from that of complex febrile…”
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Pyridoxal 5′-phosphate, pyridoxal, and 4-pyridoxic acid in the paired serum and cerebrospinal fluid of children by Akiyama, Tomoyuki, Hayashi, Yumiko, Hanaoka, Yoshiyuki, Shibata, Takashi, Akiyama, Mari, Tsuchiya, Hiroki, Yamaguchi, Tokito, Kobayashi, Katsuhiro

“…We quantified pyridoxal 5′-phosphate (PLP), pyridoxal (PL), and 4-pyridoxic acid (PA) in paired serum and cerebrospinal fluid (CSF) samples from children and…”
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Metabolic Profiling of the Cerebrospinal Fluid in Pediatric Epilepsy by Akiyama, Tomoyuki, Saigusa, Daisuke, Hyodo, Yuki, Umeda, Keiko, Saijo, Reina, Koshiba, Seizo, Kobayashi, Katsuhiro

“…To characterize metabolic profiles within the central nervous system in epilepsy, we performed gas chromatography-tandem mass spectrometry (GC-MS/MS)-based…”
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Effect of Asfotase Alfa on Muscle Weakness in a Japanese Adult Patient of Hypophosphatasia with Low ALP Levels by Koyama, Hiroyuki, Yasuda, Satoshi, Kakoi, Shota, Ohata, Yasuhisa, Shimizu, Yuki, Hasegawa, Chie, Hayakawa, Akiko, Akiyama, Tomoyuki, Yagi, Takashi, Aotani, Daisuke, Imaeda, Kenro, Ozono, Keiichi, Kataoka, Hiromi, Tanaka, Tomohiro

“…A 40-year-old Japanese woman presented to our hospital with general fatigue and muscle weakness. She had a history of premature loss of deciduous teeth at 4…”
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